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"count": 6723,
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"results": [
{
"identifier": "Spermatogenic failure Y-linked 2.",
"acronym": "SPGFY2.",
"accession": "DI-02062",
"synonyms": "Azoospermia non-obstructive Y-linked.; Non-obstructive azoospermia and infertility.; Oligospermia non-obstructive Y-linked.; Oligozoospermia non-obstructive Y-linked.; Spermatogenic arrest Y-linked.; Spermatogenic failure nonobstructive Y-linked.; ",
"cross_references": "MeSH; D053713.",
"definition": "A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 8.",
"acronym": "SPGFX8.",
"accession": "DI-06893",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "A male infertility disorder characterized by a significant reduction in progressive sperm motility, and aberrant sperm morphology. Patient sperm show head and midpiece defects with deformed and detached acrosomes, and flagellar defects. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 7.",
"acronym": "SPGFX7.",
"accession": "DI-06634",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "A male infertility disorder characterized by a significant reduction in sperm count and motility, and aberrant sperm morphology with abnormalities of the head and flagella. Patient sperm show insufficient individualization, excessive residual cytoplasm, and defects in acrosome development. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 6.",
"acronym": "SPGFX6.",
"accession": "DI-06618",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "A male infertility disorder due to asthenoteratozoospermia and characterized by reduced progressive sperm motility and morphologic sperm abnormalities, such as thin heads and short or coiled flagella. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 5.",
"acronym": "SPGFX5.",
"accession": "DI-06617",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "A male infertility disorder characterized by reduced progressive sperm motility and multiple morphologic sperm abnormalities, resulting in asthenoteratozoospermia. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 4.",
"acronym": "SPGFX4.",
"accession": "DI-06380",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "A male infertility disorder characterized by non-obstructive azoospermia or oligoasthenoteratozoospermia. Some patients present spermatogenic maturation arrest with an almost complete absence of early and late primary spermatocytes. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 3.",
"acronym": "SPGFX3.",
"accession": "DI-06023",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An infertility disorder characterized by asthenoteratozoospermia. Spermatozoa exhibit multiple morphologic abnormalities, including absent, short, coiled, and irregular-caliber flagella. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure, X-linked, 2.",
"acronym": "SPGFX2.",
"accession": "DI-04467",
"synonyms": "Male infertility from defect in meiosis.; ",
"cross_references": "MeSH; D007248.",
"definition": "An infertility disorder caused by spermatogenesis defects. It is characterized by mixed testicular atrophy and azoospermia with meiotic arrest. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 94.",
"acronym": "SPGF94.",
"accession": "DI-06911",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive, male infertility disorder characterized by reduced progressive sperm motility and multiple morphologic abnormalities of the flagella, including irregularly shaped, short, absent, coiled, and multiple tails. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 93.",
"acronym": "SPGF93.",
"accession": "DI-06910",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive, male infertility disorder characterized by asthenozoospermia and multiple morphologic abnormalities of the sperm flagella. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 92.",
"acronym": "SPGF92.",
"accession": "DI-06909",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive, male infertility disorder characterized by asthenozoospermia and defects of the radial spokes and doublet microtubules of sperm flagellum observed by ultrastructural analysis. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 91.",
"acronym": "SPGF91.",
"accession": "DI-06898",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive, male infertility disorder due to globozoospermia and asthenoteratozoospermia. Patient sperm show defects of the head, including a misshapen rounded head and detachment of the acrosome, and the sperm fail to attach to the zona pellucida of the egg. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 90.",
"acronym": "SPGF90.",
"accession": "DI-06862",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder due to severely reduced progressive motility of sperm. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 9.",
"acronym": "SPGF9.",
"accession": "DI-03123",
"synonyms": "Globozoospermia complete.; Globozoospermia total.; ",
"cross_references": "MeSH; D007248.",
"definition": "An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 89.",
"acronym": "SPGF89.",
"accession": "DI-06843",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder due to severely reduced progressive motility of sperm. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 88.",
"acronym": "SPGF88.",
"accession": "DI-06781",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder characterized by non- obstructive azoospermia due to primary spermatogenic arrest. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 87.",
"acronym": "SPGF87.",
"accession": "DI-06756",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder characterized by inability of mutant sperm to penetrate the zona pellucida, resulting in fertilization failure. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 86.",
"acronym": "SPGF86.",
"accession": "DI-06755",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder characterized by acrosomal defects of the spermatozoa, resulting in oocyte activation deficiency and fertilization failure. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 85.",
"acronym": "SPGF85.",
"accession": "DI-06752",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder characterized by globozoospermia and reduced progressive sperm motility. ",
"keywords": null
},
{
"identifier": "Spermatogenic failure 84.",
"acronym": "SPGF84.",
"accession": "DI-06699",
"synonyms": null,
"cross_references": "MeSH; D007248.",
"definition": "An autosomal recessive male infertility disorder characterized by multiple morphologic abnormalities of the sperm flagella, resulting in severely reduced motility. Some patients also have a reduced sperm count. ",
"keywords": null
}
]
}