{"count":6723,"next":"https://cinder.proteo.info/api/human_diseases/?format=json&limit=20&offset=3860&ordering=identifier","previous":"https://cinder.proteo.info/api/human_diseases/?format=json&limit=20&offset=3820&ordering=identifier","results":[{"identifier":"Macroglobulinemia, Waldenstrom, 1.","acronym":"WM1.","accession":"DI-06042","synonyms":"Macroglobulinemia, Waldenstrom, somatic.; ","cross_references":"MeSH; D008258.","definition":"A malignant B-cell neoplasm characterized by lymphoplasmacytic infiltration of the bone marrow and hypersecretion of monoclonal immunoglobulin M (IgM) protein. Clinical features are variable and include anemia, thrombocytopenia, hepatosplenomegaly, and lymphadenopathy. Many patients have asymptomatic or indolent disease. ","keywords":null},{"identifier":"Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.","acronym":"MATINS.","accession":"DI-01951","synonyms":"Alport syndrome, with macrothrombocytopenia.; BDPLT6.; Bleeding disorder platelet-type 6.; Dohle leukocyte inclusions with giant platelets.; Epstein syndrome.; EPSTNS.; Fechtner syndrome.; FTNS.; Giant platelet syndrome with thrombocytopenia.; Macrothrombocytopathy, nephritis, and deafness.; Macrothrombocytopathy-nephritis-deafness.; Macrothrombocytopenia and progressive sensorineural deafness.; Macrothrombocytopenia with leukocyte inclusions.; May-Hegglin anomaly.; MHA.; MPSD.; SBS.; Sebastian platelet syndrome.; Sebastian syndrome.; ","cross_references":"MeSH; D013921.","definition":"An autosomal dominant disorder characterized by thrombocytopenia, giant platelets and Dohle body-like inclusions in peripheral blood leukocytes with variable ultrastructural appearance. Some affected individuals lack leukocyte inclusion bodies on classic staining of peripheral blood smears. Alport syndrome-like features of nephritis, hearing loss, and eye abnormalities are present in some patients. ","keywords":null},{"identifier":"Macrothrombocytopenia, isolated, 1, autosomal dominant.","acronym":"MACTHC1.","accession":"DI-02623","synonyms":null,"cross_references":"MeSH; D013921.","definition":"A congenital blood disorder characterized by increased platelet size and decreased number of circulating platelets. ","keywords":null},{"identifier":"Macrothrombocytopenia, isolated, 2, autosomal dominant.","acronym":"MACTHC2.","accession":"DI-06398","synonyms":null,"cross_references":"MeSH; D013921.","definition":"A congenital blood disorder characterized by increased platelet size and decreased number of circulating platelets. Affected individuals usually are asymptomatic and do not have increased bleeding episodes. ","keywords":null},{"identifier":"MACS syndrome.","acronym":"MACS.","accession":"DI-02637","synonyms":"Macrocephaly alopecia cutis laxa and scoliosis syndrome.; Tall forehead, sparse hair, skin hyperextensibility, and scoliosis.; ","cross_references":"MeSH; D058627.","definition":"A complex disorder of elastic tissue characterized by sagging skin and occasionally by life-threatening visceral complications. ","keywords":null},{"identifier":"Macular degeneration, age-related, 1.","acronym":"ARMD1.","accession":"DI-00055","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 10.","acronym":"ARMD10.","accession":"DI-00063","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 11.","acronym":"ARMD11.","accession":"DI-00064","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 12.","acronym":"ARMD12.","accession":"DI-03063","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 13.","acronym":"ARMD13.","accession":"DI-03914","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 14.","acronym":"ARMD14.","accession":"DI-03919","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 15.","acronym":"ARMD15.","accession":"DI-03998","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 2.","acronym":"ARMD2.","accession":"DI-00056","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 3.","acronym":"ARMD3.","accession":"DI-00057","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 4.","acronym":"ARMD4.","accession":"DI-00058","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 5.","acronym":"ARMD5.","accession":"DI-02999","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 6.","acronym":"ARMD6.","accession":"DI-00059","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 7.","acronym":"ARMD7.","accession":"DI-00060","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 8.","acronym":"ARMD8.","accession":"DI-00061","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "},{"identifier":"Macular degeneration, age-related, 9.","acronym":"ARMD9.","accession":"DI-00062","synonyms":null,"cross_references":"MeSH; D008268.","definition":"A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. ","keywords":"KW-0913:Age-related macular degeneration.; "}]}