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"results": [
{
"accession": "PR:000025796",
"name": "integrin alpha",
"definition": "['A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif.', 'Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575].']",
"term_type": "cell line"
},
{
"accession": "GO:0005887",
"name": "integral component of plasma membrane",
"definition": "['The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.']",
"term_type": "cell line"
},
{
"accession": "GO:0016021",
"name": "integral component of membrane",
"definition": "['The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.']",
"term_type": "cell line"
},
{
"accession": "CLO:0006953",
"name": "INT 407 cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "GO:0030073",
"name": "insulin secretion",
"definition": "['The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.']",
"term_type": "cell line"
},
{
"accession": "CL:0000168",
"name": "insulin secreting cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "EFO:0001359",
"name": "insulin-dependent diabetes mellitus",
"definition": "['Diabetes mellitus characterized by insulin deficiency, sudden onset, severe hyperglycemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.']",
"term_type": "cell line"
},
{
"accession": "CL:0000217",
"name": "insulating cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:24836",
"name": "inorganic oxide",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:24835",
"name": "inorganic molecular entity",
"definition": "['A molecular entity that contains no carbon.']",
"term_type": "cell line"
},
{
"accession": "CHEBI:36914",
"name": "inorganic ion",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:33242",
"name": "inorganic hydride",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:33246",
"name": "inorganic group",
"definition": "['Any substituent group which does not contain carbon.']",
"term_type": "cell line"
},
{
"accession": "CHEBI:36915",
"name": "inorganic cation",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:24834",
"name": "inorganic anion",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:138103",
"name": "inorganic acid",
"definition": "['A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.']",
"term_type": "cell line"
},
{
"accession": "UBERON:0000087",
"name": "inner cell mass",
"definition": "['A mass of cells that develop into the body of the embryo and some extraembryonic tissues.']",
"term_type": "cell line"
},
{
"accession": "CL:0001065",
"name": "innate lymphoid cell",
"definition": "['A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.']",
"term_type": "cell line"
},
{
"accession": "GO:0045087",
"name": "innate immune response",
"definition": "['Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.']",
"term_type": "cell line"
},
{
"accession": "CHEBI:35222",
"name": "inhibitor",
"definition": "['A substance that diminishes the rate of a chemical reaction.']",
"term_type": "cell line"
}
]
}