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{
"count": 43797,
"next": "https://cinder.proteo.info/api/ms_vocab/?format=api&limit=20&offset=39860&ordering=name",
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"results": [
{
"accession": "CLO:0008486",
"name": "Pro–5 cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CL:0000826",
"name": "pro-B cell",
"definition": "['A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.', 'Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative.']",
"term_type": "cell line"
},
{
"accession": "BFO:0000015",
"name": "process",
"definition": "['An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.', 'p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])']",
"term_type": "cell line"
},
{
"accession": "OBI:0000047",
"name": "processed material",
"definition": "['Is a material entity that is created or changed during material processing.']",
"term_type": "cell line"
},
{
"accession": "UBERON:0000931",
"name": "proctodeum",
"definition": "['Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract.']",
"term_type": "cell line"
},
{
"accession": "NCBITaxon:9654",
"name": "Procyon lotor",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "GO:0002532",
"name": "production of molecular mediator involved in inflammatory response",
"definition": "['The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.']",
"term_type": "cell line"
},
{
"accession": "GO:0002440",
"name": "production of molecular mediator of immune response",
"definition": "['The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.', \"Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.\"]",
"term_type": "cell line"
},
{
"accession": "CL:0000547",
"name": "proerythroblast",
"definition": "['An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.']",
"term_type": "cell line"
},
{
"accession": "CL:0000145",
"name": "professional antigen presenting cell",
"definition": "['A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.', 'Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.']",
"term_type": "cell line"
},
{
"accession": "CL:0011026",
"name": "progenitor cell",
"definition": "['A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.']",
"term_type": "cell line"
},
{
"accession": "EFO:0000671",
"name": "progeria",
"definition": "['A very rare genetic disorder caused by mutations in the LMNA gene. It is characterized by premature aging. Signs and symptoms include failure to thrive, limited growth, alopecia, wrinkled skin, small face, development of atherosclerosis, and heart disease. There is no cure for this condition. Individuals do not usually survive beyond their early twenties. Death usually occurs as a result of complications from atherosclerosis.', 'An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.']",
"term_type": "cell line"
},
{
"accession": "GO:0012501",
"name": "programmed cell death",
"definition": "['A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.', \"Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.\"]",
"term_type": "cell line"
},
{
"accession": "DOID:891",
"name": "progressive myoclonic epilepsy",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "EFO:0002512",
"name": "progressive supranuclear palsy",
"definition": "['A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei (MeSH).']",
"term_type": "cell line"
},
{
"accession": "CL:0000385",
"name": "prohemocyte (sensu Nematoda and Protostomia)",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CHEBI:75787",
"name": "prokaryotic metabolite",
"definition": "['Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.']",
"term_type": "cell line"
},
{
"accession": "CL:0000439",
"name": "prolactin secreting cell",
"definition": "['A peptide hormone cell that secretes prolactin.']",
"term_type": "cell line"
},
{
"accession": "GO:0070459",
"name": "prolactin secretion",
"definition": "['The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.']",
"term_type": "cell line"
},
{
"accession": "UBERON:0034706",
"name": "proliferating neuroepithelium",
"definition": "['An epithelium that is undergoing proliferation to provide large numbers of neuronal cells.']",
"term_type": "cell line"
}
]
}