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{
"count": 43797,
"next": "https://cinder.proteo.info/api/ms_vocab/?format=api&limit=20&offset=41000&ordering=accession",
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"results": [
{
"accession": "GO:0003044",
"name": "regulation of systemic arterial blood pressure mediated by a chemical signal",
"definition": "['The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.']",
"term_type": "cell line"
},
{
"accession": "GO:0003073",
"name": "regulation of systemic arterial blood pressure",
"definition": "['The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.']",
"term_type": "cell line"
},
{
"accession": "GO:0003094",
"name": "glomerular filtration",
"definition": "['The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.']",
"term_type": "cell line"
},
{
"accession": "GO:0003341",
"name": "cilium movement",
"definition": "['The directed, self-propelled movement of a cilium.', 'Note that we deem cilium and microtubule-based flagellum to be equivalent.']",
"term_type": "cell line"
},
{
"accession": "GO:0003674",
"name": "molecular_function",
"definition": "['A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.', \"Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0003676",
"name": "nucleic acid binding",
"definition": "['Binding to a nucleic acid.']",
"term_type": "cell line"
},
{
"accession": "GO:0003677",
"name": "DNA binding",
"definition": "['Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).']",
"term_type": "cell line"
},
{
"accession": "GO:0004888",
"name": "transmembrane signaling receptor activity",
"definition": "['Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.', 'This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.']",
"term_type": "cell line"
},
{
"accession": "GO:0004930",
"name": "G protein-coupled receptor activity",
"definition": "['Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.']",
"term_type": "cell line"
},
{
"accession": "GO:0005215",
"name": "transporter activity",
"definition": "['Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.', \"Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0005488",
"name": "binding",
"definition": "['The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.', \"Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0005575",
"name": "cellular_component",
"definition": "['A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).', \"Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0005576",
"name": "extracellular region",
"definition": "['The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.', \"Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0005577",
"name": "fibrinogen complex",
"definition": "['A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.']",
"term_type": "cell line"
},
{
"accession": "GO:0005581",
"name": "collagen trimer",
"definition": "['A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.']",
"term_type": "cell line"
},
{
"accession": "GO:0005587",
"name": "collagen type IV trimer",
"definition": "['A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.']",
"term_type": "cell line"
},
{
"accession": "GO:0005604",
"name": "basement membrane",
"definition": "['A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.', \"Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.\"]",
"term_type": "cell line"
},
{
"accession": "GO:0005615",
"name": "extracellular space",
"definition": "['That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.', 'Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.']",
"term_type": "cell line"
},
{
"accession": "GO:0005622",
"name": "intracellular anatomical structure",
"definition": "['A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.']",
"term_type": "cell line"
},
{
"accession": "GO:0005634",
"name": "nucleus",
"definition": "[\"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.\"]",
"term_type": "cell line"
}
]
}