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{
"count": 43797,
"next": "https://cinder.proteo.info/api/ms_vocab/?format=api&limit=20&offset=600",
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"results": [
{
"accession": "CL:0000529",
"name": "pigmented epithelial cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CL:0000530",
"name": "primary neuron",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CL:0000540",
"name": "neuron",
"definition": "['The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.', 'These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma.']",
"term_type": "cell line"
},
{
"accession": "CL:0000541",
"name": "melanoblast",
"definition": "['A cell that originates from the neural crest and differentiates into a pigment cell.', 'Derived from UBERON:0002342 neural crest.']",
"term_type": "cell line"
},
{
"accession": "CL:0000542",
"name": "lymphocyte",
"definition": "['A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.', 'Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)']",
"term_type": "cell line"
},
{
"accession": "CL:0000547",
"name": "proerythroblast",
"definition": "['An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.']",
"term_type": "cell line"
},
{
"accession": "CL:0000548",
"name": "animal cell",
"definition": "[]",
"term_type": "cell line"
},
{
"accession": "CL:0000549",
"name": "basophilic erythroblast",
"definition": "['A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.']",
"term_type": "cell line"
},
{
"accession": "CL:0000550",
"name": "polychromatophilic erythroblast",
"definition": "['A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.']",
"term_type": "cell line"
},
{
"accession": "CL:0000552",
"name": "orthochromatic erythroblast",
"definition": "['The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.']",
"term_type": "cell line"
},
{
"accession": "CL:0000553",
"name": "megakaryocyte progenitor cell",
"definition": "['The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).', 'Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.']",
"term_type": "cell line"
},
{
"accession": "CL:0000556",
"name": "megakaryocyte",
"definition": "['A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm.', 'Megakaryocytes are reportedly CD181-positive and CD182-positive.']",
"term_type": "cell line"
},
{
"accession": "CL:0000557",
"name": "granulocyte monocyte progenitor cell",
"definition": "['A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1.', 'Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.']",
"term_type": "cell line"
},
{
"accession": "CL:0000558",
"name": "reticulocyte",
"definition": "['An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.']",
"term_type": "cell line"
},
{
"accession": "CL:0000559",
"name": "promonocyte",
"definition": "['A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules.', 'Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.']",
"term_type": "cell line"
},
{
"accession": "CL:0000566",
"name": "angioblastic mesenchymal cell",
"definition": "['A mesenchymal stem cell capable of developing into blood vessel endothelium.', 'These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.']",
"term_type": "cell line"
},
{
"accession": "CL:0000568",
"name": "amine precursor uptake and decarboxylation cell",
"definition": "['A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell.']",
"term_type": "cell line"
},
{
"accession": "CL:0000573",
"name": "retinal cone cell",
"definition": "['One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.']",
"term_type": "cell line"
},
{
"accession": "CL:0000576",
"name": "monocyte",
"definition": "['Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.', 'Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.']",
"term_type": "cell line"
},
{
"accession": "CL:0000578",
"name": "experimentally modified cell in vitro",
"definition": "['A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.', \"This class has been re-labeled to imply reference only to in vitro experimentally modified cells, similarly, the definition has been slightly updated to reflect this. 'experimentally modified cell' refers only to cells in vitro, and not modified in vivo/in environment cells. There is currently no class representing unmodified in vitro cells (other than the parent 'cell in vitro'), or a class representing modified native cells. More granular subclassing of experimentally modified cell can be found in ReO. MHB 1.12.12\"]",
"term_type": "cell line"
}
]
}