{"count":43797,"next":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=2500&ordering=-accession","previous":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=2460&ordering=-accession","results":[{"accession":"GO:0042221","name":"response to chemical","definition":"['Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.', 'Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.']","term_type":"cell line"},{"accession":"GO:0042113","name":"B cell activation","definition":"['The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.']","term_type":"cell line"},{"accession":"GO:0042110","name":"T cell activation","definition":"['The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.']","term_type":"cell line"},{"accession":"GO:0042105","name":"alpha-beta T cell receptor complex","definition":"['A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.']","term_type":"cell line"},{"accession":"GO:0042101","name":"T cell receptor complex","definition":"['A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.']","term_type":"cell line"},{"accession":"GO:0042092","name":"type 2 immune response","definition":"['An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.']","term_type":"cell line"},{"accession":"GO:0042073","name":"intraciliary transport","definition":"['The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.', 'Note that we deem cilium and microtubule-based flagellum to be equivalent.']","term_type":"cell line"},{"accession":"GO:0040017","name":"positive regulation of locomotion","definition":"['Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.']","term_type":"cell line"},{"accession":"GO:0040016","name":"embryonic cleavage","definition":"['The first few specialized divisions of an activated animal egg.']","term_type":"cell line"},{"accession":"GO:0040012","name":"regulation of locomotion","definition":"['Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.']","term_type":"cell line"},{"accession":"GO:0040011","name":"locomotion","definition":"['Self-propelled movement of a cell or organism from one location to another.']","term_type":"cell line"},{"accession":"GO:0038023","name":"signaling receptor activity","definition":"['Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.']","term_type":"cell line"},{"accession":"GO:0036477","name":"somatodendritic compartment","definition":"['The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.']","term_type":"cell line"},{"accession":"GO:0036160","name":"melanocyte-stimulating hormone secretion","definition":"['The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.']","term_type":"cell line"},{"accession":"GO:0035936","name":"testosterone secretion","definition":"['The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.']","term_type":"cell line"},{"accession":"GO:0035869","name":"ciliary transition zone","definition":"['A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.', \"Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.\"]","term_type":"cell line"},{"accession":"GO:0035735","name":"intraciliary transport involved in cilium assembly","definition":"['The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.']","term_type":"cell line"},{"accession":"GO:0035637","name":"multicellular organismal signaling","definition":"['The transfer of information occurring at the level of a multicellular organism.']","term_type":"cell line"},{"accession":"GO:0035592","name":"establishment of protein localization to extracellular region","definition":"['The directed movement of a protein to a specific location within the extracellular region.']","term_type":"cell line"},{"accession":"GO:0035369","name":"pre-B cell receptor complex","definition":"['An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.', 'Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome.']","term_type":"cell line"}]}