{"count":43797,"next":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=40860&ordering=accession","previous":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=40820&ordering=accession","results":[{"accession":"EFO:0000684","name":"respiratory system disease","definition":"['A body system disease that occurs in different organs functioning in respiration and consisting especially of the nose, nasal passages, nasopharynx, larynx, trachea, bronchi, and lungs.']","term_type":"cell line"},{"accession":"EFO:0000691","name":"sarcoma","definition":"['A cancer that affects connective tissue resulting in mesoderm proliferation.', 'A malignant mesenchymal neoplasm arising exclusively from the soft tissues.  Representative examples include soft tissue sarcoma, extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor, and malignant hemangiopericytoma.', 'A malignant mesenchymal neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.', 'A usually aggressive malignant mesenchymal cell tumor most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels.  Sarcomas occur in both children and adults.  The prognosis depends largely on the degree of differentiation (grade) of the tumor.  Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.\\n', 'Type of cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.']","term_type":"cell line"},{"accession":"EFO:0000692","name":"schizophrenia","definition":"['A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.']","term_type":"cell line"},{"accession":"EFO:0000697","name":"sickle cell anemia","definition":"['A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia.']","term_type":"cell line"},{"accession":"EFO:0000712","name":"cerebrovascular accident","definition":"['A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)', 'A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event.', 'A sudden, nonconvulsive loss of neurologic function due to an ischemic or hemorrhagic intracranial vascular event. In general, cerebrovascular accidents are classified by anatomic location in the brain, vascular distribution, etiology, age of the affected individual, and hemorrhagic vs. nonhemorrhagic nature (MeSH).', 'A sudden, nonconvulsive loss of neurologic function due to an ischemic or hemorrhagic intracranial vascular event. In general, cerebrovascular accidents are classified by anatomic location in the brain, vascular distribution, etiology, age of the affected individual, and hemorrhagic vs. nonhemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)']","term_type":"cell line"},{"accession":"EFO:0000729","name":"ulcerative colitis","definition":"['Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.']","term_type":"cell line"},{"accession":"EFO:0000757","name":"muscular dystrophy","definition":"['A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.']","term_type":"cell line"},{"accession":"EFO:0000783","name":"myositis","definition":"['An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.', 'Inflammation of a muscle or muscle tissue.']","term_type":"cell line"},{"accession":"EFO:0001064","name":"Down's syndrome","definition":"[\"A chromosomal dysgenesis syndrome resulting from a triplication or translocation of chromosome 21. Down syndrome occurs in approximately 1:700 live births. Abnormalities are variable from individual to individual and may include mental retardation, retarded growth, flat hypoplastic face with short nose, prominent epicanthic skin folds, small low-set ears with prominent antihelix, fissured and thickened tongue, laxness of joint ligaments, pelvic dysplasia, broad hands and feet, stubby fingers, transverse palmar crease, lenticular opacities and heart disease. Patients with Down syndrome have an estimated 10 to 30-fold increased risk for leukemia; most have symptoms of Alzheimer's disease by age 40. Also known as trisomy 21 syndrome. --2004\", 'A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe MENTAL RETARDATION. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)', 'A disorder caused by the presence of all or part of an extra 21st chromosome, characterized by structural abnormalities throughout the body. Often Down syndrome is associated with some impairment of cognitive ability and physical growth as well as facial appearance. (Adapted from Wikipedia)']","term_type":"cell line"},{"accession":"EFO:0001069","name":"nutrition disorder","definition":"['Disorders caused by nutritional imbalance, either overnutrition or undernutrition.']","term_type":"cell line"},{"accession":"EFO:0001073","name":"obesity","definition":"['A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).', 'An eating-related disorder in which excess body fat has accumulated to such an extent that health may be negatively affected. It is commonly defined as a body mass index (weight divided by height squared) of 30 kg/m2 or higher.']","term_type":"cell line"},{"accession":"EFO:0001079","name":"Rett syndrome","definition":"['An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear (MeSH).', 'An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)']","term_type":"cell line"},{"accession":"EFO:0001335","name":"disease of behavior","definition":"['A disease of or relating to the manner that an organism conducts itself involving action and response to stimulation or the response of an individual, group, or species to its environment.']","term_type":"cell line"},{"accession":"EFO:0001359","name":"insulin-dependent diabetes mellitus","definition":"['Diabetes mellitus characterized by insulin deficiency, sudden onset, severe hyperglycemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.']","term_type":"cell line"},{"accession":"EFO:0001378","name":"multiple myeloma","definition":"['A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia.  Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)\\n']","term_type":"cell line"},{"accession":"EFO:0001379","name":"endocrine system disease","definition":"['Any deviation from the normal structure or function of the endocrine system that is manifested by a characteristic set of symptoms and signs.\\n', 'Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.']","term_type":"cell line"},{"accession":"EFO:0001421","name":"liver disease","definition":"['Any disease or dysfunction of the liver and the intrahepatic bile ducts.', 'Pathological processes of the LIVER.']","term_type":"cell line"},{"accession":"EFO:0002508","name":"Parkinson's disease","definition":"[]","term_type":"cell line"},{"accession":"EFO:0002512","name":"progressive supranuclear palsy","definition":"['A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei (MeSH).']","term_type":"cell line"},{"accession":"EFO:0002616","name":"macroglobulinemia","definition":"[]","term_type":"cell line"}]}