{"count":43797,"next":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=41020&ordering=accession","previous":"https://cinder.proteo.info/api/ms_vocab/?format=json&limit=20&offset=40980&ordering=accession","results":[{"accession":"GO:0005694","name":"chromosome","definition":"['A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.', 'Chromosomes include parts that are not part of the chromatin.  Examples include the kinetochore.']","term_type":"cell line"},{"accession":"GO:0005730","name":"nucleolus","definition":"['A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.']","term_type":"cell line"},{"accession":"GO:0005737","name":"cytoplasm","definition":"['The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.']","term_type":"cell line"},{"accession":"GO:0005764","name":"lysosome","definition":"['A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.']","term_type":"cell line"},{"accession":"GO:0005766","name":"primary lysosome","definition":"['A lysosome before it has fused with a vesicle or vacuole.']","term_type":"cell line"},{"accession":"GO:0005773","name":"vacuole","definition":"['A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.']","term_type":"cell line"},{"accession":"GO:0005794","name":"Golgi apparatus","definition":"['A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.', 'Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.']","term_type":"cell line"},{"accession":"GO:0005798","name":"Golgi-associated vesicle","definition":"['Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.', 'Note that this definition includes vesicles that are transiently associated with the Golgi.']","term_type":"cell line"},{"accession":"GO:0005840","name":"ribosome","definition":"['An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.']","term_type":"cell line"},{"accession":"GO:0005856","name":"cytoskeleton","definition":"['Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.']","term_type":"cell line"},{"accession":"GO:0005874","name":"microtubule","definition":"['Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.']","term_type":"cell line"},{"accession":"GO:0005886","name":"plasma membrane","definition":"['The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.']","term_type":"cell line"},{"accession":"GO:0005887","name":"integral component of plasma membrane","definition":"['The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.']","term_type":"cell line"},{"accession":"GO:0005911","name":"cell-cell junction","definition":"['A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.']","term_type":"cell line"},{"accession":"GO:0005929","name":"cilium","definition":"['A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.', \"Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.\"]","term_type":"cell line"},{"accession":"GO:0005930","name":"axoneme","definition":"['The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.', 'Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.']","term_type":"cell line"},{"accession":"GO:0005975","name":"carbohydrate metabolic process","definition":"['The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.']","term_type":"cell line"},{"accession":"GO:0005976","name":"polysaccharide metabolic process","definition":"['The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.']","term_type":"cell line"},{"accession":"GO:0005977","name":"glycogen metabolic process","definition":"['The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.']","term_type":"cell line"},{"accession":"GO:0005978","name":"glycogen biosynthetic process","definition":"['The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.']","term_type":"cell line"}]}