{"count":543,"next":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=240","previous":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=200","results":[{"location_identifier":"Protoplasm.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0229","definition":"The protoplasm is the viscid, translucent, polyphasic colloid with water as the continuous phase that makes up the essential material of all plant and animal cells. It is composed mainly of nucleic acids, proteins, lipids, carbohydrates, and inorganic salts. The protoplasm surrounding the nucleus is known as the cytoplasm and that composing the nucleus is the nucleoplasm. ","synonyms":null,"content":"Protoplasm.","is_a":null,"part_of":null,"keyword":null,"gene_ontology":"GO:0005622; intracellular anatomical structure; ","annotation":"Not used. ","references":null,"links":null},{"location_identifier":"P-body.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0230","definition":"P-bodies are dynamic non-membrane bound cytoplasmic structures. These discrete foci function in mRNA decay (decapping and breakdown), RNA- mediated gene silencing (microRNA and siRNA-based gene silencing), mRNA surveillance (or quality control) and translational control. In addition to being sites of mRNA degradation, P-bodies can temporarily sequester mRNAs away from the translation machinery. P-bodies are present in unstressed cells, but are further induced in response to various stresses. ","synonyms":"Cytoplasmic mRNA processing body; DCP bodies; Dcp body; Gawky bodies;; Gawky body; GW182 bodies; GW182 body; GWB; GW bodies; GW body;; mRNA-decay foci; mRNA processing bodies; mRNA processing body; PB;; P bodies; P-bodies; P body; Processing bodies; Processing body.; ","content":"Cytoplasm, P-body.","is_a":"Cytoplasmic ribonucleoprotein granule.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0000932; P-body; ","annotation":null,"references":"PubMed=17183357; DOI=10.1038/nrm2080;; ","links":null},{"location_identifier":"Recycling endosome membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0231","definition":"The membrane surrounding the recycling endosomes. ","synonyms":"Recycling endosomal membrane.; ","content":"Recycling endosome membrane.","is_a":"Endosome membrane.; ","part_of":"Recycling endosome.; ","keyword":null,"gene_ontology":"GO:0055038; recycling endosome membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Recycling endosome.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0232","definition":"The recycling endosome is a membrane network composed of narrow diameters tubules which concentrate in the vicinity of the microtubule organizing center. Recycling receptors after release of their ligands accumulate in those membranes which are devoid of fluid markers. Recycling endosomes may be an intermediate station for receptors before recycling back to the cell surface. ","synonyms":"Endosomal recycling compartment; ERC.; ","content":"Recycling endosome.","is_a":null,"part_of":"Endosome.; ","keyword":null,"gene_ontology":"GO:0055037; recycling endosome; ","annotation":"Compartment specific marker: Rab11. ","references":null,"links":null},{"location_identifier":"Rhoptry.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0233","definition":"The rhoptry is an Apicomplexan parasite organelle. Apicomplexa are named for the unique set of morphologically distinct secretory organelles (refered to as the apical complex)- micronemes, rhoptries and dense granules - whose sequential secretion is required for the invasion of host cells. Rhoptries are twin, membrane-bound, pear- shaped organelles that secrete proteins through their elongated necks at the apical tip of the parasite. ","synonyms":"Rhoptries.; ","content":"Cytoplasmic vesicle, secretory vesicle, rhoptry.","is_a":"Secretory vesicle.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0020008; rhoptry; ","annotation":null,"references":null,"links":null},{"location_identifier":"Rhoptry membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0234","definition":"The membrane surrounding a rhoptry. ","synonyms":null,"content":"Cytoplasmic vesicle, secretory vesicle, rhoptry membrane.","is_a":"Secretory vesicle membrane.; ","part_of":"Rhoptry.; ","keyword":null,"gene_ontology":"GO:0033016; rhoptry membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Rough endoplasmic reticulum.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0235","definition":"The rough endoplasmic reticulum (RER) is the portion of the ER which is covered with ribosomes. ","synonyms":"RER; Rough ER.; ","content":"Rough endoplasmic reticulum.","is_a":null,"part_of":"Endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0005791; rough endoplasmic reticulum; ","annotation":null,"references":null,"links":null},{"location_identifier":"Rough endoplasmic reticulum lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0236","definition":"The rough endoplasmic reticulum lumen is the area enclosed by the rough endoplasmic reticulum membrane. ","synonyms":null,"content":"Rough endoplasmic reticulum lumen.","is_a":"Endoplasmic reticulum lumen.; ","part_of":"Rough endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0048237; rough endoplasmic reticulum lumen; ","annotation":null,"references":null,"links":null},{"location_identifier":"Rough endoplasmic reticulum membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0237","definition":"The membrane surrounding the rough endoplasmic reticulum. ","synonyms":null,"content":"Rough endoplasmic reticulum membrane.","is_a":"Endoplasmic reticulum membrane.; ","part_of":"Rough endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0030867; rough endoplasmic reticulum membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Sarcolemma.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0238","definition":"The sarcolemma is a specialized membrane which surrounds striated muscle fiber cells. It consists of a lipid bilayer typical of a plasma membrane and a thin outer coat of polysaccharide material, called glycocalyx, that contacts the basement membrane and allows the cell to anchor into the tissues that build and support muscle fibers. ","synonyms":"Myolemma.; ","content":"Cell membrane, sarcolemma.","is_a":"Cell membrane.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0042383; sarcolemma; ","annotation":null,"references":null,"links":null},{"location_identifier":"Sarcoplasmic reticulum.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0239","definition":"The sarcoplasmic reticulum (SR) is a highly specialized form of the smooth endoplasmic reticulum which is dedicated to the regulation of intracellular calcium homeostasis. The SR can be subdivided in at least two well-characterized regions: the terminal cisternae, where the calcium ions are released, and the longitudinal tubules specialized in the uptake of the calcium ions. ","synonyms":null,"content":"Sarcoplasmic reticulum.","is_a":null,"part_of":null,"keyword":"KW-0703","gene_ontology":"GO:0016529; sarcoplasmic reticulum; ","annotation":"Not ok: HI   Endoplasmic reticulum. ","references":null,"links":null},{"location_identifier":"Sarcoplasmic reticulum lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0240","definition":"The lumen of the sarcoplasmic reticulum is the area enclosed by the sarcoplasmic reticulum membrane. ","synonyms":null,"content":"Sarcoplasmic reticulum lumen.","is_a":null,"part_of":"Sarcoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0033018; sarcoplasmic reticulum lumen; ","annotation":null,"references":null,"links":null},{"location_identifier":"Sarcoplasmic reticulum membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0241","definition":"The membrane surrounding the sarcoplasmic reticulum (SR). ","synonyms":null,"content":"Sarcoplasmic reticulum membrane.","is_a":"Membrane.; ","part_of":"Endomembrane system.; Sarcoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0033017; sarcoplasmic reticulum membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secondary cell wall.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0242","definition":"In some plants, and cell types after a maximum size or point in development has been reached, a secondary wall, often layered, is constructed below the primary wall. Unlike the primary wall, it losts plasticity and is made usually of cellulose, hemicellulose and lignin. ","synonyms":null,"content":"Secreted, secondary cell wall.","is_a":"Cell wall.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0009531; secondary cell wall; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secreted.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0243","definition":"Protein located outside the cell membrane(s). ","synonyms":null,"content":"Secreted.","is_a":null,"part_of":null,"keyword":"KW-0964","gene_ontology":"GO:0005576; extracellular region; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secretory vesicle.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0244","definition":"The secretory vesicle is a vesicle that mediates the vesicular transport of cargo - e.g. hormones or neurotransmitters - from an organelle to specific sites at the cell membrane, where it docks and fuses to release its content. It has been demonstrated that membrane- bound secretory vesicles dock and fuse at porosomes, which are specialized supramolecular structures at the cell membrane. ","synonyms":"Secretory granule.; ","content":"Cytoplasmic vesicle, secretory vesicle.","is_a":"Cytoplasmic vesicle.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0030133; transport vesicle; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secretory vesicle membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0245","definition":"The membrane surrounding secretory vesicles. ","synonyms":"Secretory granule membrane.; ","content":"Cytoplasmic vesicle, secretory vesicle membrane.","is_a":"Cytoplasmic vesicle membrane.; ","part_of":"Secretory vesicle.; ","keyword":null,"gene_ontology":"GO:0030658; transport vesicle membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Septate junction.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0246","definition":"The septate junction (SJ) in invertebrates is an occluding complex located basolateral to the adherens junction which have regularly spaced septa bridging a circa 15-nm intercellular space. SJs form the paracellular barrier that regulates passage of solutes through the spaces between adjacent cells in an epithelium for proper nutrient absorption or secretion. ","synonyms":"Paired septate junction; Pleated septate junction; SJ.; ","content":"Cell junction, septate junction.","is_a":"Cell junction.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0005918; septate junction; ","annotation":"Add \"Cell membrane\" if the protein is clearly associated with the membrane. ","references":null,"links":null},{"location_identifier":"Slime layer.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0247","definition":"The slime layer is an easily removed, diffuse, unorganized layer of extracellular material which surrounds the bacterial cell. It is usually composed of polysaccharides and it may serve to trap nutrients, to aid in cell motility, to bind cells together or to adhere to smooth surfaces. Slime layers are a more-diffuse glycocalyx than capsules. ","synonyms":null,"content":"Secreted, slime layer.","is_a":null,"part_of":"Secreted.; ","keyword":null,"gene_ontology":"GO:0030114; slime layer; ","annotation":null,"references":null,"links":null},{"location_identifier":"Smooth endoplasmic reticulum.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0248","definition":"The smooth endoplasmic reticulum (SER) is the portion of the ER which is free of ribosomes. ","synonyms":"SER; Smooth ER.; ","content":"Smooth endoplasmic reticulum.","is_a":null,"part_of":"Endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0005790; smooth endoplasmic reticulum; ","annotation":null,"references":null,"links":null}]}