{"count":543,"next":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=500&ordering=location_identifier","previous":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=460&ordering=location_identifier","results":[{"location_identifier":"Secreted.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0243","definition":"Protein located outside the cell membrane(s). ","synonyms":null,"content":"Secreted.","is_a":null,"part_of":null,"keyword":"KW-0964","gene_ontology":"GO:0005576; extracellular region; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secretory vesicle.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0244","definition":"The secretory vesicle is a vesicle that mediates the vesicular transport of cargo - e.g. hormones or neurotransmitters - from an organelle to specific sites at the cell membrane, where it docks and fuses to release its content. It has been demonstrated that membrane- bound secretory vesicles dock and fuse at porosomes, which are specialized supramolecular structures at the cell membrane. ","synonyms":"Secretory granule.; ","content":"Cytoplasmic vesicle, secretory vesicle.","is_a":"Cytoplasmic vesicle.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0030133; transport vesicle; ","annotation":null,"references":null,"links":null},{"location_identifier":"Secretory vesicle lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0347","definition":"The secretory vesicle compartment bounded by the membrane of the secretory vesicle. ","synonyms":"Secretory granule lumen.; ","content":"Cytoplasmic vesicle, secretory vesicle lumen.","is_a":"Cytoplasmic vesicle lumen.; ","part_of":"Secretory vesicle.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Secretory vesicle membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0245","definition":"The membrane surrounding secretory vesicles. ","synonyms":"Secretory granule membrane.; ","content":"Cytoplasmic vesicle, secretory vesicle membrane.","is_a":"Cytoplasmic vesicle membrane.; ","part_of":"Secretory vesicle.; ","keyword":null,"gene_ontology":"GO:0030658; transport vesicle membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Septate junction.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0246","definition":"The septate junction (SJ) in invertebrates is an occluding complex located basolateral to the adherens junction which have regularly spaced septa bridging a circa 15-nm intercellular space. SJs form the paracellular barrier that regulates passage of solutes through the spaces between adjacent cells in an epithelium for proper nutrient absorption or secretion. ","synonyms":"Paired septate junction; Pleated septate junction; SJ.; ","content":"Cell junction, septate junction.","is_a":"Cell junction.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0005918; septate junction; ","annotation":"Add \"Cell membrane\" if the protein is clearly associated with the membrane. ","references":null,"links":null},{"location_identifier":"S-layer.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0262","definition":"The S-layer is a paracrystalline protein thin layer attached to the outermost portion of the cell wall. Found in some bacteria and common in archaea where it can constitute the only cell wall structure outside the plasma membrane. In Gram-negative bacteria, the S-layer is directly attached to the outer membrane. In Gram-positive bacteria, the S-layer is attached to the peptidoglycan layer. The S-layer may protect the cell from aggressions such as phagocytosis, harmful enzymes, etc. It also allows bacteria to adhere to host cells or other environmental surfaces and to maintain shape and envelope rigidity. ","synonyms":null,"content":"Secreted, cell wall, S-layer.","is_a":null,"part_of":"Cell wall.; ","keyword":"KW-0701","gene_ontology":"GO:0030115; S-layer; ","annotation":null,"references":null,"links":null},{"location_identifier":"Slime layer.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0247","definition":"The slime layer is an easily removed, diffuse, unorganized layer of extracellular material which surrounds the bacterial cell. It is usually composed of polysaccharides and it may serve to trap nutrients, to aid in cell motility, to bind cells together or to adhere to smooth surfaces. Slime layers are a more-diffuse glycocalyx than capsules. ","synonyms":null,"content":"Secreted, slime layer.","is_a":null,"part_of":"Secreted.; ","keyword":null,"gene_ontology":"GO:0030114; slime layer; ","annotation":null,"references":null,"links":null},{"location_identifier":"Smooth endoplasmic reticulum.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0248","definition":"The smooth endoplasmic reticulum (SER) is the portion of the ER which is free of ribosomes. ","synonyms":"SER; Smooth ER.; ","content":"Smooth endoplasmic reticulum.","is_a":null,"part_of":"Endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0005790; smooth endoplasmic reticulum; ","annotation":null,"references":null,"links":null},{"location_identifier":"Smooth endoplasmic reticulum lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0249","definition":"The smooth endoplasmic reticulum lumen is the area enclosed by the smooth endoplasmic reticulum membrane. ","synonyms":null,"content":"Smooth endoplasmic reticulum lumen.","is_a":"Endoplasmic reticulum lumen.; ","part_of":"Smooth endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0048238; smooth endoplasmic reticulum lumen; ","annotation":null,"references":null,"links":null},{"location_identifier":"Smooth endoplasmic reticulum membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0250","definition":"The membrane surrounding the smooth endoplasmic reticulum. ","synonyms":null,"content":"Smooth endoplasmic reticulum membrane.","is_a":"Endoplasmic reticulum membrane.; ","part_of":"Smooth endoplasmic reticulum.; ","keyword":null,"gene_ontology":"GO:0030868; smooth endoplasmic reticulum membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spindle.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0251","definition":"The spindle is a specialized microtubule structure designed to attach and capture chromosomes in order to partition them evenly to each daughter cells. ","synonyms":"Meiotic spindle; Mitotic apparatus; Mitotic spindle.; ","content":"Cytoplasm, cytoskeleton, spindle.","is_a":null,"part_of":"Cytoskeleton.; ","keyword":null,"gene_ontology":"GO:0005819; spindle; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spindle pole.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0448","definition":"Either of the ends of a spindle, a specialized microtubule structure designed to attach and capture chromosomes in order to partition them evenly to each daughter cells. ","synonyms":null,"content":"Cytoplasm, cytoskeleton, spindle pole.","is_a":null,"part_of":"Spindle.; ","keyword":null,"gene_ontology":"GO:0000922; spindle pole; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spindle pole body.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0252","definition":"The spindle pole body is the microtubule organizing center (MTOC) in fungi, functionally equivalent to the animal cell centrosome. The SPB is responsible for the nucleation and organisation of microtubules. This may include the spindle microtubules required for chromosome segregation in mitosis and meiosis as well as the cytoplasmic interphase microtubules. ","synonyms":"SPB; Spindle polar body.; ","content":"Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.","is_a":null,"part_of":"Microtubule organizing center.; ","keyword":null,"gene_ontology":"GO:0005816; spindle pole body; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spine apparatus.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0530","definition":"Specialized form of endoplasmic reticulum found in a subpopulation of dendritic spines in central neurons consisting of two or more closely apposed lamellae with interspersed electron dense material. ","synonyms":null,"content":"Endoplasmic reticulum, spine apparatus.","is_a":"Endoplasmic reticulum.; ","part_of":"Dendritic spine.; Postsynapse.; ","keyword":null,"gene_ontology":"GO:0097444; spine apparatus; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spore.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0539","definition":"Spores are hardy unicellular units used by various bacteria, fungi, plants and protozoa to allow them to remain dormant during long periods of time and under often unfavorable conditions. ","synonyms":"Ascospore; Basidiospore; Chlamydospore; Megaspore; Microspore;; Teliospore; Tetraspore; Zoospore.; ","content":"Spore.","is_a":null,"part_of":null,"keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Spore coat.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0366","definition":"Protein found in the spore coat. The spore coat is the thick layer found beneath the perispore of some eukaryotic spores and bacterial mature spores. It is made up of highly cross-linked keratin and layers of specific proteins. The coat is composed of several electron-dense and lamella-like layers, differing between species. ","synonyms":null,"content":"Spore coat.","is_a":null,"part_of":"Spore.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Spore core.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0253","definition":"Protein found in the spore core. The core also called spore matrix is the central part of the spore and contains normal cell structures, such as DNA, proteins and ribosomes, but is metabolically inactive. ","synonyms":null,"content":"Spore core.","is_a":null,"part_of":"Spore.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Spore cortex.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0364","definition":"Protein found in the spore cortex. The spore cortex is a loosely cross-linked peptidoglycan layer localized between the spore core and the outer membrane or cortex membrane of bacterial mature spores. The cortex maintains heat resistance and dormancy. ","synonyms":null,"content":"Spore cortex.","is_a":null,"part_of":"Spore.; ","keyword":null,"gene_ontology":"GO:0043595; endospore cortex; ","annotation":null,"references":null,"links":null},{"location_identifier":"Spore membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0363","definition":"Protein associated with the membrane that surrounds the center or core of a spore, often called spore inner membrane in bacterial spores. ","synonyms":"Spore inner membrane.; ","content":"Spore membrane.","is_a":"Membrane.; ","part_of":"Spore.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Spore outer membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0365","definition":"Protein associated with the spore outer membrane. The outer membrane, also called the cortex membrane, is a membrane localized between the cortex and the inner layer of the coat of bacterial mature spores. ","synonyms":null,"content":"Spore outer membrane.","is_a":"Membrane.; ","part_of":"Spore.; ","keyword":null,"gene_ontology":"GO:0043594; outer endospore membrane; ","annotation":null,"references":null,"links":null}]}