{"count":543,"next":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=100&ordering=-synonyms","previous":"https://cinder.proteo.info/api/subcellular_locations/?format=json&limit=20&offset=60&ordering=-synonyms","results":[{"location_identifier":"Coated pit.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0072","definition":"Coated pits are regions of the donor membrane where the assembly of the vesicle coat take place. The coat assembles from soluble protomers such as coat protein complex-I and coat protein complex-II. The components of the coat often define the intracellular sorting station, and contribute to both membrane deformation and local movement of the resulting transport intermediate following scission. During the first steps of the vesicle-mediated membrane transport, coated pits are internalized to form coated vesicles which transport proteins between distinct membrane-bound organelles. ","synonyms":null,"content":"Membrane, coated pit.","is_a":null,"part_of":"Endomembrane system.; ","keyword":"KW-0168","gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Cyanelle stroma.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0350","definition":"The internal space enclosed by the cyanelle double membrane but excluding the thylakoid space. This space, filled with a colorless hydrophilic matrix, contains DNA, ribosomes and some temporary products of photosynthesis. ","synonyms":null,"content":"Plastid, cyanelle stroma.","is_a":"Plastid stroma.; ","part_of":"Cyanelle.; ","keyword":null,"gene_ontology":"GO:0034060; cyanelle stroma; ","annotation":null,"references":null,"links":null},{"location_identifier":"Apical lamina.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0016","definition":"In the sea urchin embryos the apical lamina is a fibrous meshwork that remains after removal of hyalin from the hyalin layer. ","synonyms":null,"content":"Secreted, extracellular space, extracellular matrix, apical lamina.","is_a":"Extracellular matrix.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0032579; apical lamina of hyaline layer; ","annotation":null,"references":null,"links":null},{"location_identifier":"Cytoplasmic granule lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0324","definition":"The cytoplasmic granule compartment bounded by the cytoplasmic granule membrane. ","synonyms":null,"content":"Cytoplasmic granule lumen.","is_a":null,"part_of":"Cytoplasmic granule.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Barrier septum.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0454","definition":"The barrier septum, is a septum which spans a cell and does not allow exchange of organelles or cytoplasm between compartments. ","synonyms":null,"content":"Barrier septum.","is_a":"Cell septum.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0000935; division septum; ","annotation":null,"references":null,"links":null},{"location_identifier":"Chlorosome.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0059","definition":"The chlorosome is a photosynthetic light-harvesting complex found in anoxygenic green bacteria. Chlorosomes are flattened ellipsoidal organelles appressed to the cytoplasmic face of the cell membrane. They typically contain highly aggregated bacteriochlorophyll c, d, or e (Bchl), a small amount of Bchl a, carotenoids, quinones, and occasionally wax esters. The chlorosome envelope of green sulfur bacteria is an asymmetric membrane containing galactolipids with the galactosyl moieties exposed on the outer surface. The farnesyl tails of the BChl molecules within the chlorosome probably comprise the inner leaflet of this membrane. ","synonyms":null,"content":"Chlorosome.","is_a":null,"part_of":null,"keyword":"KW-0151","gene_ontology":"GO:0046858; chlorosome; ","annotation":null,"references":"PubMed=16866355; DOI=10.1021/bi060776y;; ","links":null},{"location_identifier":"Cleavage furrow.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0467","definition":"In fungal, amoeboid and animal cells, during the cytokinesis at the end of cell division, a cleavage furrow forms in the plasma membrane. A contractile ring containing actin and myosin is assembled at the selected site of the future cleavage furrow. Ring contraction produces the force to constrict the cleavage furrow and the daughter cells separate by membrane fusion. ","synonyms":null,"content":"Cleavage furrow.","is_a":null,"part_of":null,"keyword":null,"gene_ontology":"GO:0032154; cleavage furrow; ","annotation":null,"references":null,"links":null},{"location_identifier":"Chromaffin granule.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0061","definition":"A chromaffin granule is a specialized secretory vesicle characteristic of chromaffin cells. ","synonyms":null,"content":"Cytoplasmic vesicle, secretory vesicle, chromaffin granule.","is_a":"Secretory vesicle.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0042583; chromaffin granule; ","annotation":null,"references":null,"links":null},{"location_identifier":"Basement membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0025","definition":"The basement membrane is a highly specialized extracellular matrix structure undelying the basal surface of cells exhibiting polarity (epithelial, endothelial and mesothelial cells) and surrounding certain cell types such as muscle, adipose and Schwann cells. ","synonyms":null,"content":"Secreted, extracellular space, extracellular matrix, basement membrane.","is_a":"Extracellular matrix.; ","part_of":null,"keyword":"KW-0084","gene_ontology":"GO:0005604; basement membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Cvt vesicle membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0081","definition":"The membrane surrounding a cvt vesicle. A cvt vesicle is a double membrane-layered vesicle implicated in the cytoplasm to vacuole targeting pathway. ","synonyms":null,"content":"Cytoplasmic vesicle, cvt vesicle membrane.","is_a":"Cytoplasmic vesicle membrane.; ","part_of":"Cvt vesicle.; ","keyword":null,"gene_ontology":"GO:0033110; Cvt vesicle membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Chromoplast.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0063","definition":"A chromoplast is a plastid containing pigments other than chlorophyll. Found in flower, petals and fruit. ","synonyms":null,"content":"Plastid, chromoplast.","is_a":"Plastid.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0009509; chromoplast; ","annotation":null,"references":null,"links":null},{"location_identifier":"Cornified envelope.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0079","definition":"The cornified envelope is a structure which is formed beneath the plasma membrane in terminally differentiating stratified squamous epithelia. It provides a vital physical barrier to these tissues in mammals and consists of a 10 nm thick layer of highly crosslinked insoluble proteins. In the specialized case of the epidermis, a 5 nm thick layer of ceramide lipids is covalently bound to the proteins. These organize extracellular lipids into orderly lamellae and, together, the cell envelope and extracellular lipids are essential for effective physical and water barrier function in the skin. ","synonyms":null,"content":"Cornified envelope.","is_a":null,"part_of":null,"keyword":null,"gene_ontology":"GO:0001533; cornified envelope; ","annotation":null,"references":null,"links":null},{"location_identifier":"Bleb.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0472","definition":"These cellular membrane protrusions are the result of actomyosin contractions of the cortex, which cause either transient detachment of the cell membrane from the actin cortex or a rupture in the actin cortex. Then, cytosol streams out of the cell body and inflates the newly formed bleb. Once expansion slows, an actin cortex is reconstituted. Retraction is powered by myosin motor proteins. Blebbing is a common feature of cell physiology during cell movement, cytokinesis, cell spreading and apoptosis. ","synonyms":null,"content":"Cell projection, bleb.","is_a":"Cell projection.; ","part_of":null,"keyword":null,"gene_ontology":"GO:0032059; bleb; ","annotation":null,"references":"PubMed=17318224; DOI=10.1038/nrm2122;; ","links":null},{"location_identifier":"Cytoskeleton.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0090","definition":"The cytoskeleton is a dynamic three-dimensional filamentous structure in the cytoplasm. Its roles include maintenance of cell shape, cell movement (in eukaryotes), cytokinesis, and the organization of organelles or organelle-like structures within the cell. The cytoskeleton includes microfilaments (actin-like proteins), microtubules (tubulin-like proteins), the intermediate filaments (mostly in eukaryotes) and the MinD-ParA proteins, which appear to be unique to prokaryotes. ","synonyms":null,"content":"Cytoplasm, cytoskeleton.","is_a":null,"part_of":"Cytoplasm.; ","keyword":"KW-0206","gene_ontology":"GO:0005856; cytoskeleton; ","annotation":null,"references":null,"links":null},{"location_identifier":"Apoplast.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0019","definition":"The apoplast is the \"non-living\" extracellular space that surrounds the symplast. It consists of cell walls and spaces between cells. Water and solutes can move freely in this framework, except at the endodermis in roots and stems where the apoplastic flow of ions is interrupted by the Casparian strip, forcing water to flow to symplast. ","synonyms":null,"content":"Secreted, extracellular space, apoplast.","is_a":"Extracellular space.; ","part_of":null,"keyword":"KW-0052","gene_ontology":"GO:0048046; apoplast; ","annotation":null,"references":null,"links":null},{"location_identifier":"Cyanelle thylakoid lumen.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0084","definition":"The cyanelle thylakoid lumen is the cyanelle compartment bounded by the thylakoid membranes. ","synonyms":null,"content":"Plastid, cyanelle thylakoid lumen.","is_a":"Plastid thylakoid lumen.; ","part_of":"Cyanelle thylakoid.; ","keyword":null,"gene_ontology":"GO:0033114; cyanelle thylakoid lumen; ","annotation":null,"references":null,"links":null},{"location_identifier":"Cytoplasm.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0086","definition":"The cytoplasm is the content of a cell within the plasma membrane and, in eukaryotics cells, surrounding the nucleus. This three-dimensional, jelly-like lattice interconnects and supports the other solid structures. The cytosol (the soluble portion of the cytoplasm outside the organelles) is mostly composed of water and many low molecular weight compounds. In eukaryotes, the cytoplasm also contains a network of cytoplasmic filaments (cytoskeleton). ","synonyms":null,"content":"Cytoplasm.","is_a":null,"part_of":null,"keyword":"KW-0963","gene_ontology":"GO:0005737; cytoplasm; ","annotation":null,"references":null,"links":null},{"location_identifier":"Extracellular vesicle membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0500","definition":"The membrane surrounding an extracellular vesicle. ","synonyms":null,"content":"Extracellular vesicle membrane.","is_a":"Membrane.; ","part_of":"Extracellular vesicle.; ","keyword":null,"gene_ontology":null,"annotation":null,"references":null,"links":null},{"location_identifier":"Cyanelle outer membrane.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0482","definition":"The outer membrane of a cyanelle is the cyanelle membrane facing the cytoplasm. ","synonyms":null,"content":"Plastid, cyanelle outer membrane.","is_a":"Cyanelle membrane.; Plastid outer membrane.; ","part_of":"Cyanelle envelope.; ","keyword":null,"gene_ontology":"GO:0036013; cyanelle outer membrane; ","annotation":null,"references":null,"links":null},{"location_identifier":"Host endosome.","topology_identifier":null,"orientation_identifier":null,"accession":"SL-0393","definition":"Host endosomes are highly dynamic membrane systems involved in transport within the host cell, they receive endocytosed host cell membrane molecules and sort them for either degradation or recycling back to the host cell surface. They also receive newly synthesised proteins destined for host vacuolar/lysosomal compartments. ","synonyms":null,"content":"Host endosome.","is_a":null,"part_of":"Host cell.; ","keyword":"KW-1039","gene_ontology":"GO:0044174; host cell endosome; ","annotation":null,"references":null,"links":null}]}