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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=120&ordering=synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=80&ordering=synonyms",
"results": [
{
"location_identifier": "Recycling endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0232",
"definition": "The recycling endosome is a membrane network composed of narrow diameters tubules which concentrate in the vicinity of the microtubule organizing center. Recycling receptors after release of their ligands accumulate in those membranes which are devoid of fluid markers. Recycling endosomes may be an intermediate station for receptors before recycling back to the cell surface. ",
"synonyms": "Endosomal recycling compartment; ERC.; ",
"content": "Recycling endosome.",
"is_a": null,
"part_of": "Endosome.; ",
"keyword": null,
"gene_ontology": "GO:0055037; recycling endosome; ",
"annotation": "Compartment specific marker: Rab11. ",
"references": null,
"links": null
},
{
"location_identifier": "Cell envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0036",
"definition": "The cell envelope comprises the cell membrane, the cell wall and an outer membrane if present. In bacteria with 1 membrane (Gram-positive) the cell envelope consists of the cytoplasmic membrane, cell wall and capsule. In bacteria with 2 membranes (Gram-negative) the envelope consists of the cytoplasmic membrane, cell wall, periplasmic space, outer membrane and capsule. The archaeal cell envelope generally consists of single membrane covered by a surface layer (S-layer). Ignicoccus species exceptionally have an outer membrane which encloses a large periplasmic space. Extreme thermophiles and acidophiles have tetraether type glycerophospholipids with C40 isoprenoid chains. The yeast cell envelope is a protecting capsule which consists of the cytoplasmic membrane, the periplasmic space, and the cell wall. ",
"synonyms": "Envelope.; ",
"content": "Cell envelope.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030313; cell envelope; ",
"annotation": "Try to use a child/narrower/more specific term instead ",
"references": null,
"links": "http://www.cf.ac.uk/biosi/staff/ehrmann/tools/ecce/ecce.htm; "
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0098",
"definition": "The ER-Golgi intermediate compartment is a collection of tubulovesicular membrane clusters in the vicinity of ER exit sites. The ERGIC mediates transport between the endoplasmic reticulum and the Golgi and is the first anterograde/retrograde sorting station in the secretory pathway. ERGIC has not been observed in yeast and plants. ",
"synonyms": "ERGIC; ER-Golgi intermediate compartment; IC;; Intermediate compartment; Vesiculo-tubular cluster; VTC.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005793; endoplasmic reticulum-Golgi intermediate compartment; ",
"annotation": "Compartment specific marker: LMAN1/ERGIC-53 (Also called P-58). ",
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0326",
"definition": "The ERGIC compartment bounded by the ERGIC membrane. ",
"synonyms": "ERGIC lumen; ER-Golgi intermediate compartment lumen; IC lumen;; Intermediate compartment lumen; Vesiculo-tubular cluster lumen;; VTC lumen.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment lumen.",
"is_a": null,
"part_of": "Endoplasmic reticulum-Golgi intermediate compartment.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0099",
"definition": "The membrane surrounding the ER-Golgi intermediate compartment, which is a collection of tubulovesicular membrane clusters in the vicinity of ER exit sites. ",
"synonyms": "ERGIC membrane; ER-Golgi intermediate compartment membrane;; IC membrane; Intermediate compartment membrane;; Vesiculo-tubular cluster membrane; VTC membrane.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment membrane.",
"is_a": "Membrane.; ",
"part_of": "Endoplasmic reticulum-Golgi intermediate compartment.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0033116; endoplasmic reticulum-Golgi intermediate compartment membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Esterosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0328",
"definition": "The esterosomal compartment bounded by the esterosomal membrane. ",
"synonyms": "Esterosomal lumen.; ",
"content": "Cytoplasmic vesicle, esterosome lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Esterosome.; ",
"keyword": null,
"gene_ontology": "GO:0034467; esterosome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Esterosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0108",
"definition": "The membrane surrounding the esterosome, a crystalline inclusion body is a vesicle filled with crystals of proteins showing sequence similarities with various esterases. ",
"synonyms": "Esterosomal membrane.; ",
"content": "Cytoplasmic vesicle, esterosome membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "Esterosome.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0033118; esterosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Prolamellar body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0226",
"definition": "The prolamellar body is a paracrystalline lattice found in the plastids of etiolated plants (etioplasts). Upon greening it gives rise to thylakoids. ",
"synonyms": "Etioplast prolamellar body.; ",
"content": "Plastid, etioplast, prolamellar body.",
"is_a": null,
"part_of": "Etioplast.; ",
"keyword": null,
"gene_ontology": "GO:0009541; etioplast prolamellar body; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Perispore.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0367",
"definition": "Protein found in the perispore. The perispore corresponds to the outer surface layer of mature bacterial spores and eukaryotic spores. The perispore, also called perine or exosporium, represents the primary contact surface between the spore and environment/host and is a site of spore antigens. ",
"synonyms": "Exosporium; Perine.; ",
"content": "Spore, perispore.",
"is_a": null,
"part_of": "Spore.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Extracellular exosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0466",
"definition": "Exosomes are 30-120 nm microvesicles of endocytic origin secreted by most cell types and found in abundance in body fluids, including blood, saliva, urine, and breast milk. They contain various molecular constituents of their cell of origin, including proteins and nucleic acids, and carry this cargo between diverse locations in the body. These microvesicles form by budding into the lumen of the multivesicular bodies (MVBs) and are released to extracellular fluids by fusion of MVBs with the plasma membrane. ",
"synonyms": "Extracellular vesicular exosome.; ",
"content": "Secreted, extracellular exosome.",
"is_a": null,
"part_of": "Secreted.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": "http://exocarta.ludwig.edu.au/; "
},
{
"location_identifier": "Filopodium membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0287",
"definition": "The portion of the cell membrane surrounding the filopodium. The filopodium is a thin, tubular, finger-like cell protrusion filled with straight bundled, crosslinked actin filaments having their barbed ends directed towards the cell membrane. ",
"synonyms": "Filopodia membrane; Microspike membrane.; ",
"content": "Cell projection, filopodium membrane.",
"is_a": null,
"part_of": "Cell membrane.; Filopodium.; ",
"keyword": null,
"gene_ontology": "GO:0031527; filopodium membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Filopodium.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0286",
"definition": "The filopodium is a thin, tubular, finger-like cell protrusion filled with straight bundled, crosslinked actin filaments having their barbed ends directed towards the cell membrane. Filopodium are observed at the advancing front of the migrating cell and are implicated in cell motility as well as in cell-substrate adhesion. Filopodia explore the environment and form nascent adhesive structures in response to external signaling cues. These long and highly dynamic protrusions, which can extend and retract, are involved in mesenchymal migration. They are observed in many cell types, such as amoebae, keratinocytes, fibroblasts and in neurite growth cones. ",
"synonyms": "Filopodia; Microspike.; ",
"content": "Cell projection, filopodium.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030175; filopodium; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Filopodium tip.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0470",
"definition": "The end of the filopodium distal to the body of the cell. The filopodium is a thin, tubular, finger-like cell protrusion filled with straight bundled, crosslinked actin filaments having their barbed ends directed towards the cell membrane. ",
"synonyms": "Filopodia tip; Microspike tip.; ",
"content": "Cell projection, filopodium tip.",
"is_a": null,
"part_of": "Filopodium.; ",
"keyword": null,
"gene_ontology": "GO:0032433; filopodium tip; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Fimbrium.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0113",
"definition": "A fimbrium or pilus is a hair-like, non-flagellar, polymeric filamentous appendage that extend from the bacterial or archaeal cell surface, such as type 1 pili, P-pili, type IV pili or curli. Pili perform a variety of functions, including surface adhesion, motility, cell-cell interactions, biofilm formation, conjugation, DNA uptake, and twitching motility. ",
"synonyms": "Fimbria; Pili; Pilus.; ",
"content": "Fimbrium.",
"is_a": null,
"part_of": null,
"keyword": "KW-0281",
"gene_ontology": "GO:0009289; pilus; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Flagellum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0117",
"definition": "The flagellum is a long whip-like or feathery structure which propels the cell through a liquid medium. This motile cilium is produced by the unicellular eukaryotes, and by the motile male gametes of many eukaryotic organisms. The flagella commonly have a characteristic axial '9+2' microtubular array (axoneme) and bends are generated along the length of the flagellum by restricted sliding of the nine outer doublets. ",
"synonyms": "Flagella; Motile cilia; Motile cilium; Undulipodia; Undulipodium.; ",
"content": "Cell projection, cilium, flagellum.",
"is_a": "Cilium.; ",
"part_of": null,
"keyword": "KW-0282",
"gene_ontology": "GO:0031514; motile cilium; ",
"annotation": null,
"references": null,
"links": "http://www.ciliome.com; "
},
{
"location_identifier": "Flagellum axoneme.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0114",
"definition": "The flagellum axoneme is the most prominent structural component of the flagellum, which is a long whip-like or feathery structure which propels the cell through a liquid medium. The flagellum axoneme consists of a characteristic axial '9+2' microtubular array. ",
"synonyms": "Flagellar axoneme.; ",
"content": "Cytoplasm, cytoskeleton, flagellum axoneme.",
"is_a": "Cilium axoneme.; ",
"part_of": "Flagellum.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Flagellum basal body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0308",
"definition": "The basal body is a barrel-shaped microtubule-based structure required for the formation of flagella. Basal bodies, structuraly related to and often interconvertible with centrioles, serves as a nucleation site for axoneme growth. ",
"synonyms": "Flagellar basal body; Flagellar kinetosome; Flagellum kinetosome.; ",
"content": "Cytoplasm, cytoskeleton, flagellum basal body.",
"is_a": "Cilium basal body.; ",
"part_of": "Flagellum.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Flagellum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0115",
"definition": "The portion of the cell membrane surrounding the flagellum, a long whip-like or feathery structure which propels the cell through a liquid medium. ",
"synonyms": "Flagellar membrane.; ",
"content": "Cell projection, cilium, flagellum membrane.",
"is_a": "Cilium membrane.; ",
"part_of": "Flagellum.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Midbody ring.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0490",
"definition": "The midbody ring is the central region of the midbody characterized by a gap in alpha-tubulin staining, although interdigitating microtubules persist through the gap. It is thought that high local protein density masks tubulin epitopes known to be present. The midbody ring serves as a scaffold for a wide variety of structural and regulatory proteins required for completion of cytokinesis. ",
"synonyms": "Flemming body; Stembody.; ",
"content": "Midbody, Midbody ring.",
"is_a": "Midbody.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0090543; Flemming body; ",
"annotation": "Some authors consider that Flemming body and Midbody are synonyms. This is not the case in UniProtKB, where we use Flemming body as a synonym for Midbody ring, a specific part of the midbody. If you have doubt, use the broader term, Midbody. ",
"references": null,
"links": null
},
{
"location_identifier": "Glycosome matrix.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0332",
"definition": "The glycosomal compartment bounded by the membrane of the glycosome, a specialized peroxisome found in all members of the protist order Kinetoplastida examined. ",
"synonyms": "Glycosomal lumen; Glycosomal matrix; Glycosome lumen.; ",
"content": "Glycosome matrix.",
"is_a": "Peroxisome matrix.; ",
"part_of": "Glycosome.; ",
"keyword": null,
"gene_ontology": "GO:0034468; glycosome lumen; ",
"annotation": null,
"references": null,
"links": null
}
]
}