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"count": 543,
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"results": [
{
"location_identifier": "Nucleoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0187",
"definition": "The nucleoid is the prokaryotic pseudocompartment formed by the chromatin-dense area. This region, which is functionally equivalent to the eukaryotic nucleus, is not surrounded by a membrane. ",
"synonyms": null,
"content": "Cytoplasm, nucleoid.",
"is_a": null,
"part_of": "Cytoplasm.; ",
"keyword": null,
"gene_ontology": "GO:0009295; nucleoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Nuclear pore complex.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0185",
"definition": "The nuclear pore complex (NPC) constitutes the exclusive means of nucleocytoplasmic transport in eukaryotes during interphase. NPCs allow the passive diffusion of ions and small molecules (up to about 20 kDa or 5 nm) and the active, nuclear transport receptor (karyopherin: importin and exportin)-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoprotein (RNPs), and ribosomal subunits (up to about 10 MDa) across the double-membrane nuclear envelope. NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. The NPC is composed of at least 30 distinct subunits, shows 8-fold rotational symmetry with specialized structures on the cyto- and nucleoplasmic side and in the nuclear envelope embedded core. The MW varies from about 44-60 MDa in S. cerevisiae to 60-120 MDa in vertebrates, yet the overall architecture is conserved. ",
"synonyms": "NPC; Nuclear pore.; ",
"content": "Nucleus, nuclear pore complex.",
"is_a": null,
"part_of": "Nucleus envelope.; ",
"keyword": "KW-0906",
"gene_ontology": "GO:0005643; nuclear pore; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Nuclear body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0494",
"definition": "Nuclear body is a collective term for several nuclear, extra- nucleolar, non-membrane-bound sub-compartments, including, but not limited to Cajal bodies, Gemini of Cajal bodies (gems), nuclear speckles and PML bodies. Nuclear bodies are visible as distinct spots in the nucleoplasm. They can vary in number and size depending on the cell line and the type of nuclear body. ",
"synonyms": null,
"content": "Nucleus, nuclear body.",
"is_a": null,
"part_of": "Nucleus.; ",
"keyword": null,
"gene_ontology": "GO:0016604; nuclear body; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Neuron projection.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0518",
"definition": "Prolongation or process extending from a nerve cell, such as an axon or a dendrite. Used when speaking of immature or developing neurons, especially of cells in culture, because it can be difficult to tell axons from dendrites before differentiation is complete. ",
"synonyms": "Neurite; Neuronal process.; ",
"content": "Cell projection, neuron projection.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0043005; neuron projection; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Neuronal dense core vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0532",
"definition": "The membrane surrounding a neuronal dense core vesicle. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Neuronal dense core vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0099012; neuronal dense core vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Neuronal dense core vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0526",
"definition": "Dense core vesicle that is part of a neuron. Stores and releases neuropeptides (peptide neurotransmitters) and neurotrophins by exocytosis. Filled with cargo at the Golgi network, they are transported through axons and dendrites to the synapses where the release takes place. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. ",
"synonyms": "Large dense-core vesicles; Neuronal dense core granule;; Neuronal large dense-core vesicles.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0098992; neuronal dense core vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Nematocyst.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0177",
"definition": "The nematocyst is an organelle found in nematoblast (cnidoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the nematocyst) is stimulated by a prey or another stimulus. These proteins are principally found in anemones and jellyfishes. ",
"synonyms": "Cnidocyst.; ",
"content": "Nematocyst.",
"is_a": null,
"part_of": null,
"keyword": "KW-0166",
"gene_ontology": "GO:0042151; nematocyst; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Myofibril.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0312",
"definition": "A myofibril is a long cylindrical organelle found in muscle cells formed by two transverse filament systems: the thick and thin filaments. The thin filament is composed primarily of actin; it is tethered at one end to the Z-disk, and it interdigitates with the thick filaments. The main constituent of the thick filament is myosin; the direction of the myosin heads changes polarity at the M-line, allowing interaction with the thin filaments anchored from the next adjacent Z-disk. A third and a fourth filament complex exist, comprising the giant proteins titin and nebulin. ",
"synonyms": null,
"content": "Cytoplasm, myofibril.",
"is_a": "Sarcoplasm.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030016; myofibril; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Myelin membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0176",
"definition": "The myelin membrane is the white matter coating our nerves, enabling them to conduct impulses between the brain and other parts of the body. It consists of a layer of proteins packed between two layers of lipids. This specialized cell membrane is produced by oligodendrocytes in the central nervous system, and Schwann cells in the peripheral nervous system. Myelin sheaths wrap themselves around axons, the threadlike extensions of neurons that make up nerve fibers. Each oligodendrocyte can myelinate several axons. The major function of myelin is to increase the velocity of propagation of nerve impulses. ",
"synonyms": "Myelin; Myelin sheath.; ",
"content": "Myelin membrane.",
"is_a": "Cell membrane.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0043209; myelin sheath; ",
"annotation": null,
"references": null,
"links": "https://www.myelin.org/; "
},
{
"location_identifier": "Multivesicular body membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0175",
"definition": "The membrane surrounding the multivesicular bodies. ",
"synonyms": "Corpuscula multivesicularis membrane; ECV membrane;; Endosomal carrier vesicle membrane; Multivesicular bodies membrane;; MVB membrane.; ",
"content": "Endosome, multivesicular body membrane.",
"is_a": "Endosome membrane.; ",
"part_of": "Multivesicular body.; ",
"keyword": null,
"gene_ontology": "GO:0032585; multivesicular body membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Multivesicular body lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0340",
"definition": "The multivesicular body compartment bounded by the membrane of the multivesicular bodies. ",
"synonyms": "Corpuscula multivesicularis lumen; ECV lumen;; Endosomal carrier vesicle lumen; Multivesicular bodies lumen;; MVB lumen.; ",
"content": "Endosome, multivesicular body lumen.",
"is_a": "Endosome lumen.; ",
"part_of": "Multivesicular body.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Multivesicular body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0174",
"definition": "The multivesicular bodies are a type of late endosome containing internal vesicles formed following the inward budding of the outer endosomal membrane. The contents of the MVBs are then released into the lysosome lumen. The proteins found in the limiting membrane of MVBs are recycled to other compartments. ",
"synonyms": "Corpuscula multivesicularis; ECV; Endosomal carrier vesicle;; Multivesicular bodies; MVB.; ",
"content": "Endosome, multivesicular body.",
"is_a": "Late endosome.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005771; multivesicular body; ",
"annotation": null,
"references": null,
"links": "http://www.uni-mainz.de/FB/Medizin/Anatomie/workshop/EM/EMMVBE.html; "
},
{
"location_identifier": "M line.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0315",
"definition": "In electron micrographs of the sarcomere, the M line appears as a series of parallel electron-dense lines in the central zone of the A band impliing that the M line is needed for the regular packing of the thick filaments. The M line maintains the myosin filaments in a hexagonal lattice. ",
"synonyms": "M band; M-band; M-line.; ",
"content": "Cytoplasm, myofibril, sarcomere, M line.",
"is_a": null,
"part_of": "H zone.; ",
"keyword": null,
"gene_ontology": "GO:0031430; M band; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
},
{
"location_identifier": "Mitosome outer membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0443",
"definition": "The outer membrane of a mitosome is the mitosomal membrane facing the cytoplasm. ",
"synonyms": "Mitosomal outer membrane; Outer mitosomal membrane.; ",
"content": "Mitosome outer membrane.",
"is_a": "Mitosome membrane.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0442",
"definition": "The membrane surrounding a mitosome. This term is used when it is not known if the protein is found in or associated with the inner or outer mitosomal membrane. ",
"synonyms": "Mitosomal membrane.; ",
"content": "Mitosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Mitosome envelope.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome matrix.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0441",
"definition": "The matrix of a mitosome is the mitosomal internal spaces enclosed by the inner membrane. ",
"synonyms": "Mitosomal matrix.; ",
"content": "Mitosome matrix.",
"is_a": null,
"part_of": "Mitosome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome intermembrane space.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0440",
"definition": "The mitosomal intermembrane space is the space between inner and outer mitosomal membranes. ",
"synonyms": "Mitosomal intermembrane space; Mitosomal periplasm;; Mitosomal periplasmic space.; ",
"content": "Mitosome intermembrane space.",
"is_a": null,
"part_of": "Mitosome envelope.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome inner membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0439",
"definition": "The inner membrane of a mitosome is the membrane which separates the mitosomal matrix from the intermembrane space. ",
"synonyms": "Inner mitosomal membrane; Mitosomal inner membrane.; ",
"content": "Mitosome inner membrane.",
"is_a": "Mitosome membrane.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0438",
"definition": "The mitosomal envelope comprises the inner and outer mitosomal membrane including the intermembrane space. ",
"synonyms": "Mitosomal envelope.; ",
"content": "Mitosome envelope.",
"is_a": null,
"part_of": "Mitosome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0437",
"definition": "The mitosome is an organelle found in \"amitochondrial\" unicellular organisms which do not have the capability of gaining energy from oxidative phosphorylation. Mitosomes are almost certainly derived from mitochondria, they have a double membrane and most proteins are delivered to them by a targeting sequence. Unlike mitochondria, mitosomes do not contain any DNA. The mitosome functions in iron- sulphur cluster assembly. ",
"synonyms": null,
"content": "Mitosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-1025",
"gene_ontology": "GO:0032047; mitosome; ",
"annotation": null,
"references": null,
"links": null
}
]
}