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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=220&ordering=location_identifier",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=180&ordering=location_identifier",
"results": [
{
"location_identifier": "Golgi apparatus lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0133",
"definition": "The Golgi lumen consist of the cisternal spaces (or internal lumen) of the Golgi apparatus. ",
"synonyms": "Apparatus golgiensis lumen; Complexus golgiensis lumen;; Golgi complex lumen; Golgi lumen.; ",
"content": "Golgi apparatus lumen.",
"is_a": null,
"part_of": "Golgi apparatus.; ",
"keyword": null,
"gene_ontology": "GO:0005796; Golgi lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Golgi apparatus membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0134",
"definition": "The membrane surrounding the Golgi apparatus. ",
"synonyms": "Apparatus golgiensis membrane; Complexus golgiensis membrane;; Golgi complex membrane; Golgi membrane.; ",
"content": "Golgi apparatus membrane.",
"is_a": "Membrane.; ",
"part_of": "Golgi apparatus.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0000139; Golgi membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Golgi outpost.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0521",
"definition": "Golgi outpost is an organelle that shares common markers with the perinuclear Golgi body, but is typically much smaller in size and located far from the nucleus or cell body. Golgi outposts can function as acentrosomal microtubule-organizing centers (MTOCs) and play specialized roles in building the cytoarchitecture of neuronal dendrites, muscle cells, and oligodendrocytes. ",
"synonyms": "Golgi elements; Golgi vesicles; Mini Golgi;; Postsynaptic Golgi apparatus; Satellite Golgi.; ",
"content": "Golgi outpost.",
"is_a": "Golgi apparatus.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": "PubMed=32863092 ",
"references": null,
"links": null
},
{
"location_identifier": "Golgi stack.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0135",
"definition": "The Golgi stack consist of a series of flattened curved and parallel series saccules, called cisternae or dictyosomes, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack. ",
"synonyms": "Dictyosome; Golgi bodies; Golgi body.; ",
"content": "Golgi apparatus, Golgi stack.",
"is_a": null,
"part_of": "Golgi apparatus.; ",
"keyword": null,
"gene_ontology": "GO:0005795; Golgi stack; ",
"annotation": "Compartment specific marker: Mannosidase II. ",
"references": null,
"links": null
},
{
"location_identifier": "Golgi stack lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0334",
"definition": "The Golgi stack compartment bounded by the membrane of the Golgi stack. ",
"synonyms": "Dictyosome lumen; Golgi bodies lumen; Golgi body lumen.; ",
"content": "Golgi apparatus, Golgi stack lumen.",
"is_a": "Golgi apparatus lumen.; ",
"part_of": "Golgi stack.; ",
"keyword": null,
"gene_ontology": "GO:0034469; Golgi stack lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Golgi stack membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0136",
"definition": "The membrane surrounding the Golgi stack. ",
"synonyms": "Dictyosome membrane; Golgi bodies membrane; Golgi body membrane;; Golgi cisterna membrane.; ",
"content": "Golgi apparatus, Golgi stack membrane.",
"is_a": "Golgi apparatus membrane.; ",
"part_of": "Golgi stack.; ",
"keyword": null,
"gene_ontology": "GO:0032580; Golgi cisterna membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Growth cone.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0288",
"definition": "The growth cone is a dynamic cell protrusion at the tip of the extending axon or dendrite. Neuron extends a specialized structure, the growth cone, to find targets in the wiring of the nervous system. The growth cone explores its environment by extending dynamic filopodia. Growth cone is composed of an ensemble of protruding and retracting veils (lamellipodia), net growth cone advance may be considered the vector sum of all veil's motility behavior in response to their local environments. Filopodia play a key role in delimiting veils and serving to nucleate the formation of new veils. ",
"synonyms": null,
"content": "Cell projection, growth cone.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030426; growth cone; ",
"annotation": null,
"references": "PubMed=17327278; DOI=10.1242/jcs.03384;; ",
"links": null
},
{
"location_identifier": "Growth cone membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0289",
"definition": "The portion of the cell membrane surrounding a growth cone. ",
"synonyms": null,
"content": "Cell projection, growth cone membrane.",
"is_a": null,
"part_of": "Cell membrane.; Growth cone.; ",
"keyword": null,
"gene_ontology": "GO:0032584; growth cone membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Hemidesmosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0137",
"definition": "The hemidesmosome is an integrin-containing adhesive junction located along the basal layer of cells where they abut the basement membrane zone. As the name implies, only half the desmosome is present; only one cell is participating, the second cell being represented by the basement membrane. ",
"synonyms": null,
"content": "Cell junction, hemidesmosome.",
"is_a": "Cell junction.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030056; hemidesmosome; ",
"annotation": "Add \"Cell membrane\" if the protein is clearly associated with the membrane. ",
"references": null,
"links": "http://celljunctions.med.nyu.edu/hemidesmosomes/hemimain.html; "
},
{
"location_identifier": "Host.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0431",
"definition": "The host is any organism in which another organism, or symbiont, spends part or all of its life cycle. Most animals and plants live symbiotically with microorganisms. The larger organism is called the host and smaller organism the symbiont. When the interactions between the symbiont and the host benefits both partners, the symbiotic interaction is called mutualism. When there is a negative effect on one of the partners, it is called a parasitic symbiosis and if there is no beneficial or negative effect it is a commensal symbiosis. These clear-cut definitions are not always easy to apply in nature. Take the bacterium Pseudomonas aeruginosa for example. This bacterium can be found on the skin of humans and not cause disease, perhaps we would call it a commensial, but if the person has a severe burn P. aeruginosa can cause an infection and becomes a pathogen (a medicinal term for parasitism). This type of organism is called an opportunistic pathogen. Whether an association is a mutualist, commensal or parasitic depends on the relative \"strengths\" of the partners and the balance of power can change over time. ",
"synonyms": null,
"content": "Host.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0018995; host cellular component; ",
"annotation": null,
"references": null,
"links": "http://web.uconn.edu/mcbstaff/graf/GenSym/GenSym.htm; "
},
{
"location_identifier": "Host apical cell membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0372",
"definition": "The fraction of the host cell membrane at the apical end of the host cell, which faces the outside world or the lumen of the host cavity. ",
"synonyms": "Host apical plasma membrane.; ",
"content": "Host apical cell membrane.",
"is_a": null,
"part_of": "Host cell membrane.; ",
"keyword": null,
"gene_ontology": "GO:0020002; host cell plasma membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host basolateral cell membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0459",
"definition": "The fraction of the host cell membrane at the basolateral side of the cell, which faces adjacent host cells and the underlying host connective tissue. ",
"synonyms": "Host basolateral plasma membrane.; ",
"content": "Host basolateral cell membrane.",
"is_a": null,
"part_of": "Host cell membrane.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host caveola.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0428",
"definition": "The host caveola is a small (apparently) uncoated pit found mostly in the host cell membrane of many highly differentiated mammalian cells, such as adipocytes, endothelial cells and muscle cells. These flask- shaped invaginations are defined by the presence of caveolins and contains a subset of lipid-raft components, including cholesterol and sphingolipids. ",
"synonyms": "Host caveolae; Host membrane microdomain; Host plasmalemmal vesicle.; ",
"content": "Host membrane, host caveola.",
"is_a": null,
"part_of": "Host endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0044155; host caveola; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0427",
"definition": "A cell within a host organism including the host cell membrane and any external encapsulating structures such as the host cell wall and cell envelope. ",
"synonyms": null,
"content": "Host cell.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0043657; host cell; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0421",
"definition": "The host cell envelope comprises the cell membrane, the cell wall and an outer membrane if present. The Gram-positive bacteria host cell envelope consists of the cytoplasmic membrane, cell wall and capsule. The Gram-negative host envelope consists of the cytoplasmic membrane, cell wall, periplasmic space, outer membrane and capsule. The archaeal cell host envelope consists generally of single typical bilayer membrane covered by a surface layer (S-layer). Ignicoccus host species exceptionally have an outer membrane which encloses a large periplasmic space. Extreme host thermophiles and acidophiles have tetraether type glycerophospholipids with C40 isoprenoid chains. The yeast host cell envelope is a protecting capsule which consists of the cytoplasmic membrane, the periplasmic space, and the cell wall. ",
"synonyms": "Host envelope.; ",
"content": "Host cell envelope.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": null,
"gene_ontology": "GO:0044230; host cell envelope; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell inner membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0373",
"definition": "The prokaryotic host cell inner membrane is the selectively permeable membrane which separates the host cytoplasm from the host periplasm in prokaryotes with 2 membranes. ",
"synonyms": "Host inner membrane.; ",
"content": "Host cell inner membrane.",
"is_a": "Host cell membrane.; ",
"part_of": null,
"keyword": "KW-1030",
"gene_ontology": "GO:0020002; host cell plasma membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell junction.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0374",
"definition": "The host cell junction is a host cell-host cell or host cell-host extracellular matrix contact within a tissue of a host multicellular organism, especially abundant in host epithelia. In vertebrates, there are three major types of cell junctions: anchoring junctions (e.g. adherens junctions), communicating junctions (e.g. gap junctions) and occluding junctions (e.g. tight junctions). ",
"synonyms": null,
"content": "Host cell junction.",
"is_a": null,
"part_of": "Host.; ",
"keyword": "KW-1031",
"gene_ontology": "GO:0044156; host cell junction; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0375",
"definition": "The host cell membrane is the selectively permeable membrane which separates the host cytoplasm from its surroundings. Known as the host cell inner membrane in prokaryotes with 2 membranes. ",
"synonyms": "Host cytoplasmic membrane; Host plasmalemma; Host plasma membrane.; ",
"content": "Host cell membrane.",
"is_a": "Host membrane.; ",
"part_of": "Host endomembrane system.; Host cell envelope.; ",
"keyword": "KW-1032",
"gene_ontology": "GO:0020002; host cell plasma membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell outer membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0376",
"definition": "The prokaryotic host cell outer membrane is the selectively permeable membrane which separates the prokaryotic periplasm from its surroundings in prokaryotes with 2 membranes. Traditionally only Gram- negative bacteria were thought of as having an outer membrane, but recent work has shown some Actinobacteria, including Mycobacterium tuberculosis, as well as at least 1 archaea (Ignicoccus hospitalis) have a cell outer membrane. ",
"synonyms": "Host outer membrane.; ",
"content": "Host cell outer membrane.",
"is_a": "Host membrane.; ",
"part_of": null,
"keyword": "KW-1033",
"gene_ontology": "GO:0020002; host cell plasma membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell projection.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0377",
"definition": "A host cell projection is a host cell protrusion such as pseudopodium, filopodium, lamellipodium, growth cone, flagellum, acrosome, axon, pili or bacterial comet tail. These membrane-cytoskeleton-coupled processes are involved in many biological functions, such as host cell motility, cancer-cell invasion, endocytosis, phagocytosis, exocytosis, pathogen infection, neurite extension and cytokinesis. ",
"synonyms": "Host cell protrusion.; ",
"content": "Host cell projection.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1034",
"gene_ontology": "GO:0044157; host cell projection; ",
"annotation": null,
"references": null,
"links": null
}
]
}