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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=280",
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"results": [
{
"location_identifier": "Mitochondrion nucleoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0269",
"definition": "The mitochondrial nucleoid is the mitochondrial pseudocompartment formed by the chromatin-dense area. This region, which is functionally equivalent to the eukaryotic nucleus, is not surrounded by a membrane. ",
"synonyms": "Mitochondrial nucleoid; Mitochromosome.; ",
"content": "Mitochondrion matrix, mitochondrion nucleoid.",
"is_a": null,
"part_of": "Mitochondrion matrix.; ",
"keyword": "KW-1135",
"gene_ontology": "GO:0042645; mitochondrial nucleoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Vacuole lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0270",
"definition": "The lumen of a vacuole is the area enclosed by the vacuolar membrane. ",
"synonyms": "Vacuolar lumen.; ",
"content": "Vacuole lumen.",
"is_a": null,
"part_of": "Vacuole.; ",
"keyword": null,
"gene_ontology": "GO:0005775; vacuolar lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Vacuole membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0271",
"definition": "The membrane surrounding a vacuole. ",
"synonyms": "Vacuolar membrane.; ",
"content": "Vacuole membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Vacuole.; ",
"keyword": null,
"gene_ontology": "GO:0005774; vacuolar membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Vacuole.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0272",
"definition": "The vacuole is a generally large fluid-filled membrane-bound compartment in the cytoplasm. The precise form and function of vacuoles may vary between phyla. Plant vacuoles are among the best characterized. They differ in terms of their lumenal contents and processing enzymes, as well as on the basis of the type of integral proteins in their membranes (tonoplast intrinsic proteins, TIPs). Examples include the lytic vacuole, the storage vacuole and the lutoid. One important function of plant vacuoles is the maintenance of hydrostatic pressure. Other eukaryotes employ vacuoles for a variety of purposes, including storage (as in the yeast lysosome/vacuole), secretion and phagocytosis. In Protozoa, contractile vacuoles can be used to discharge water from the cytoplasm to the external environment. ",
"synonyms": null,
"content": "Vacuole.",
"is_a": null,
"part_of": null,
"keyword": "KW-0926",
"gene_ontology": "GO:0005773; vacuole; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Virion tegument.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0273",
"definition": "The viral tegument is a protein structure that resides between the capsid and envelope of herpesviruses and which appears amorphous in electron micrographs. ",
"synonyms": "Viral tegument.; ",
"content": "Virion tegument.",
"is_a": null,
"part_of": "Virion.; ",
"keyword": "KW-0920",
"gene_ontology": "GO:0019033; viral tegument; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Virion.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0274",
"definition": "The virion is the complete fully infectious extracellular virus particle. ",
"synonyms": null,
"content": "Virion.",
"is_a": null,
"part_of": null,
"keyword": "KW-0946",
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Virion membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0275",
"definition": "The membrane surrounding the virion. ",
"synonyms": null,
"content": "Virion membrane.",
"is_a": "Membrane.; ",
"part_of": "Virion.; ",
"keyword": null,
"gene_ontology": "GO:0055036; virion membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Telomere.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0276",
"definition": "The telomere is a nucleoprotein structure comprising the terminal section of a eukaryotic chromosome. It has a specialized structure which is replicated by a special process, thereby counteracting the tendency of a chromosome to be shortened during each round of replication. ",
"synonyms": "Chromosome, telomeric region.; ",
"content": "Chromosome, telomere.",
"is_a": null,
"part_of": "Chromosome.; ",
"keyword": "KW-0779",
"gene_ontology": "GO:0000781; chromosome, telomeric region; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cyanelle thylakoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0277",
"definition": "The cyanelle thylakoid is an internal system of interconnected photosynthetic membranes resembling that of cyanobacteria found in the cyanelles of certain algae. ",
"synonyms": null,
"content": "Plastid, cyanelle thylakoid.",
"is_a": "Plastid thylakoid.; ",
"part_of": "Cyanelle.; ",
"keyword": null,
"gene_ontology": "GO:0009843; cyanelle thylakoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Plastid thylakoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0278",
"definition": "The thylakoid of a plastid is an internal system of interconnected membranes found within a plastid. ",
"synonyms": "Plastidic thylakoid.; ",
"content": "Plastid thylakoid.",
"is_a": "Thylakoid.; ",
"part_of": "Plastid.; ",
"keyword": null,
"gene_ontology": "GO:0031976; plastid thylakoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Axon.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0279",
"definition": "The axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. ",
"synonyms": "Axon shaft.; ",
"content": "Cell projection, axon.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030424; axon; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cell projection.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0280",
"definition": "A cell projection is a cell protrusion such as pseudopodium, filopodium, lamellipodium, growth cone, flagellum, acrosome, axon, or bacterial comet tail. These membrane-cytoskeleton-coupled processes are involved in many biological functions, such as cell motility, cancer-cell invasion, endocytosis, phagocytosis, exocytosis, pathogen infection, neurite extension and cytokinesis. ",
"synonyms": "Cell protrusion.; ",
"content": "Cell projection.",
"is_a": null,
"part_of": null,
"keyword": "KW-0966",
"gene_ontology": "GO:0042995; cell projection; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0281",
"definition": "Protein found in or associated with cytoplasmic granules. ",
"synonyms": null,
"content": "Cytoplasmic granule.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0282",
"definition": "The membrane surrounding a cytoplasmic granule. ",
"synonyms": null,
"content": "Cytoplasmic granule membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Cytoplasmic granule.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Dendrite.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0283",
"definition": "The dendrite is a short and typically branched process extending from the cell body of a neuron that receives and integrates signals coming from axons of other neurons, and conveys the resulting signal to the body of the cell. ",
"synonyms": null,
"content": "Cell projection, dendrite.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030425; dendrite; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Dendritic spine.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0284",
"definition": "A dendritic spine is a small, club-like cell protrusion from neuronal dendrites that form the postsynaptic component of most excitatory synapses in the brain. Spines are complex, dynamic structures that contain a dense array of cytoskeletal, transmembrane, and scaffolding molecules. Despite their modest size, most spines contain at least some form of smooth endoplasmic reticulum, which in the largest spines takes the form of a specialized organelle called the \"spine apparatus\". These cell protrusions play a critical role in synaptic transmission and plasticity. ",
"synonyms": "Postsynaptic dendritic spine; Spine.; ",
"content": "Cell projection, dendritic spine.",
"is_a": "Postsynapse.; ",
"part_of": "Neuron projection.; ",
"keyword": null,
"gene_ontology": "GO:0043197; dendritic spine; ",
"annotation": null,
"references": "PubMed=16443821; DOI=10.1152/physiol.00042.2005;; ",
"links": null
},
{
"location_identifier": "Dendritic spine membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0285",
"definition": "The portion of the cell membrane surrounding the dendritic spine, a small, club-like cell protrusion from neuronal dendrites that form the postsynaptic component of most excitatory synapses in the brain. ",
"synonyms": null,
"content": "Cell projection, dendritic spine membrane.",
"is_a": "Postsynaptic cell membrane.; ",
"part_of": "Dendritic spine.; ",
"keyword": null,
"gene_ontology": "GO:0032591; dendritic spine membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Filopodium.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0286",
"definition": "The filopodium is a thin, tubular, finger-like cell protrusion filled with straight bundled, crosslinked actin filaments having their barbed ends directed towards the cell membrane. Filopodium are observed at the advancing front of the migrating cell and are implicated in cell motility as well as in cell-substrate adhesion. Filopodia explore the environment and form nascent adhesive structures in response to external signaling cues. These long and highly dynamic protrusions, which can extend and retract, are involved in mesenchymal migration. They are observed in many cell types, such as amoebae, keratinocytes, fibroblasts and in neurite growth cones. ",
"synonyms": "Filopodia; Microspike.; ",
"content": "Cell projection, filopodium.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030175; filopodium; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Filopodium membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0287",
"definition": "The portion of the cell membrane surrounding the filopodium. The filopodium is a thin, tubular, finger-like cell protrusion filled with straight bundled, crosslinked actin filaments having their barbed ends directed towards the cell membrane. ",
"synonyms": "Filopodia membrane; Microspike membrane.; ",
"content": "Cell projection, filopodium membrane.",
"is_a": null,
"part_of": "Cell membrane.; Filopodium.; ",
"keyword": null,
"gene_ontology": "GO:0031527; filopodium membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Growth cone.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0288",
"definition": "The growth cone is a dynamic cell protrusion at the tip of the extending axon or dendrite. Neuron extends a specialized structure, the growth cone, to find targets in the wiring of the nervous system. The growth cone explores its environment by extending dynamic filopodia. Growth cone is composed of an ensemble of protruding and retracting veils (lamellipodia), net growth cone advance may be considered the vector sum of all veil's motility behavior in response to their local environments. Filopodia play a key role in delimiting veils and serving to nucleate the formation of new veils. ",
"synonyms": null,
"content": "Cell projection, growth cone.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030426; growth cone; ",
"annotation": null,
"references": "PubMed=17327278; DOI=10.1242/jcs.03384;; ",
"links": null
}
]
}