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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=320",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=280",
"results": [
{
"location_identifier": "Plastid thylakoid lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0309",
"definition": "The plastid thylakoid lumen is the plastid compartment bounded by the thylakoid membranes. ",
"synonyms": "Plastid thylakoidal lumen.; ",
"content": "Plastid thylakoid lumen.",
"is_a": null,
"part_of": "Plastid thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0031978; plastid thylakoid lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cell surface.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0310",
"definition": "The outermost side of the cell. ",
"synonyms": null,
"content": "Cell surface.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009986; cell surface; ",
"annotation": "Try to use a child/narrower/more specific term instead ",
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0311",
"definition": "The sarcoplasm is the cytoplasm of a muscle fiber or muscle cell or myofiber. ",
"synonyms": null,
"content": "Cytoplasm, sarcoplasm.",
"is_a": "Cytoplasm.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0016528; sarcoplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Myofibril.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0312",
"definition": "A myofibril is a long cylindrical organelle found in muscle cells formed by two transverse filament systems: the thick and thin filaments. The thin filament is composed primarily of actin; it is tethered at one end to the Z-disk, and it interdigitates with the thick filaments. The main constituent of the thick filament is myosin; the direction of the myosin heads changes polarity at the M-line, allowing interaction with the thin filaments anchored from the next adjacent Z-disk. A third and a fourth filament complex exist, comprising the giant proteins titin and nebulin. ",
"synonyms": null,
"content": "Cytoplasm, myofibril.",
"is_a": "Sarcoplasm.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030016; myofibril; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcomere.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0313",
"definition": "The sarcomere represents the basal contractile unit of striated muscles. A single myofibril is composed of these short structural units arranged end to end, which contract due to the relative sliding of thick (myosin) over thin (actin) filaments. The mammalian sarcomere is ~ 2 mm in length, and can shorten to ~ 70% of its original length during contraction. Structural features of the sarcomere include bundles of parallel thick and thin filaments assembled by two transverse structures, the Z lines and M lines. The Z lines and the M lines are connected by transverse filaments to the sarcolemma or to the neighboring myofibrils. Sarcomeres give to skeletal and cardiac muscles their striated appearance with I bands surrounding the Z lines, followed by A bands. The A bands contain a paler region called the H zone and in the middle the M line. ",
"synonyms": null,
"content": "Cytoplasm, myofibril, sarcomere.",
"is_a": null,
"part_of": "Myofibril.; ",
"keyword": null,
"gene_ontology": "GO:0030017; sarcomere; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
},
{
"location_identifier": "Z line.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0314",
"definition": "Z-disks are the lateral boundaries of a single sarcomere. In electron micrographs of cross striated muscle the Z line appears as a series of dark lines. They represent a key interface between the contractile apparatus and the cytoskeleton. The Z line (from the German \"Zwischen\") largely consists of alpha-actinin homodimers organized in an antiparallel fashion, thereby providing a backbone for the insertions of actin-based thin filaments, as well as titin and nebulin/nebulette. Z line of neighbouring sarcomeres are aligned in parallel and connected via the intermediate filament protein desmin. They maintain the actin filaments in a tetragonal lattice. ",
"synonyms": "Z-band; Z bodies; Z body; Z disc; Z-disc; Z disk; Z-disk; Z-line.; ",
"content": "Cytoplasm, myofibril, sarcomere, Z line.",
"is_a": null,
"part_of": "I band.; ",
"keyword": null,
"gene_ontology": "GO:0030018; Z disc; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "M line.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0315",
"definition": "In electron micrographs of the sarcomere, the M line appears as a series of parallel electron-dense lines in the central zone of the A band impliing that the M line is needed for the regular packing of the thick filaments. The M line maintains the myosin filaments in a hexagonal lattice. ",
"synonyms": "M band; M-band; M-line.; ",
"content": "Cytoplasm, myofibril, sarcomere, M line.",
"is_a": null,
"part_of": "H zone.; ",
"keyword": null,
"gene_ontology": "GO:0031430; M band; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
},
{
"location_identifier": "Acidocalcisome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0316",
"definition": "The acidocalcisome compartment bounded by the acidocalcisomal membrane. ",
"synonyms": "Acidocalcisomal lumen.; ",
"content": "Acidocalcisome lumen.",
"is_a": null,
"part_of": "Acidocalcisome.; ",
"keyword": null,
"gene_ontology": "GO:0033985; acidocalcisome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Aleurone grain lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0317",
"definition": "The aleurone grain compartment bounded by the aleurone grain membrane. ",
"synonyms": "Protein body lumen.; ",
"content": "Vacuole, aleurone grain lumen.",
"is_a": "Vacuole lumen.; ",
"part_of": "Aleurone grain.; ",
"keyword": null,
"gene_ontology": "GO:0034422; aleurone grain lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Autophagosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0318",
"definition": "The autophagosomal compartment bounded by the autophagosomal membrane. ",
"synonyms": "Autophagic vacuolar lumen; Autophagic vacuole lumen;; Autophagosomal lumen.; ",
"content": "Cytoplasmic vesicle, autophagosome lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Autophagosome.; ",
"keyword": null,
"gene_ontology": "GO:0034423; autophagosome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0319",
"definition": "The clathrin-coated vesicle compartment bounded by the clathrin-coated vesicle membrane. ",
"synonyms": "Clathrin-coated vesicular lumen.; ",
"content": "Cytoplasmic vesicle, clathrin-coated vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Clathrin-coated vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Contractile vacuole lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0320",
"definition": "The contractile vacuole compartment bounded by the contractile vacuole membrane. ",
"synonyms": "Contractile vacuolar lumen.; ",
"content": "Contractile vacuole lumen.",
"is_a": "Vacuole lumen.; ",
"part_of": "Contractile vacuole.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPI-coated vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0321",
"definition": "The COPI-coated vesicle compartment bounded by the COPI-coated vesicle membrane. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, COPI-coated vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "COPI-coated vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPII-coated vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0322",
"definition": "The COPII-coated vesicle compartment bounded by the COPII-coated vesicle membrane. ",
"synonyms": "Coat protein complexes II lumen; ER to Golgi transport vesicle lumen.; ",
"content": "Cytoplasmic vesicle, COPII-coated vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "COPII-coated vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cvt vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0323",
"definition": "The cvt vesicle compartment bounded by the cvt vesicle membrane. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, cvt vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Cvt vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic granule lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0324",
"definition": "The cytoplasmic granule compartment bounded by the cytoplasmic granule membrane. ",
"synonyms": null,
"content": "Cytoplasmic granule lumen.",
"is_a": null,
"part_of": "Cytoplasmic granule.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0325",
"definition": "The cytoplasmic vesicle compartment bounded by the cytoplasmic vesicle membrane. ",
"synonyms": null,
"content": "Cytoplasmic vesicle lumen.",
"is_a": null,
"part_of": "Cytoplasmic vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0060205; cytoplasmic vesicle lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0326",
"definition": "The ERGIC compartment bounded by the ERGIC membrane. ",
"synonyms": "ERGIC lumen; ER-Golgi intermediate compartment lumen; IC lumen;; Intermediate compartment lumen; Vesiculo-tubular cluster lumen;; VTC lumen.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment lumen.",
"is_a": null,
"part_of": "Endoplasmic reticulum-Golgi intermediate compartment.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0327",
"definition": "The endosomal compartment bounded by the endosomal membrane. ",
"synonyms": "Endosomal lumen.; ",
"content": "Endosome lumen.",
"is_a": null,
"part_of": "Endosome.; ",
"keyword": null,
"gene_ontology": "GO:0031904; endosome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Esterosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0328",
"definition": "The esterosomal compartment bounded by the esterosomal membrane. ",
"synonyms": "Esterosomal lumen.; ",
"content": "Cytoplasmic vesicle, esterosome lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Esterosome.; ",
"keyword": null,
"gene_ontology": "GO:0034467; esterosome lumen; ",
"annotation": null,
"references": null,
"links": null
}
]
}