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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=340&ordering=-synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=300&ordering=-synonyms",
"results": [
{
"location_identifier": "Mitosome intermembrane space.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0440",
"definition": "The mitosomal intermembrane space is the space between inner and outer mitosomal membranes. ",
"synonyms": "Mitosomal intermembrane space; Mitosomal periplasm;; Mitosomal periplasmic space.; ",
"content": "Mitosome intermembrane space.",
"is_a": null,
"part_of": "Mitosome envelope.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitosome envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0438",
"definition": "The mitosomal envelope comprises the inner and outer mitosomal membrane including the intermembrane space. ",
"synonyms": "Mitosomal envelope.; ",
"content": "Mitosome envelope.",
"is_a": null,
"part_of": "Mitosome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion outer membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0172",
"definition": "The outer membrane of a mitochondrion is the mitochondrial membrane facing the cytoplasm. ",
"synonyms": "Mitochondrial outer membrane; Outer mitochondrial membrane.; ",
"content": "Mitochondrion outer membrane.",
"is_a": "Mitochondrion membrane.; ",
"part_of": null,
"keyword": "KW-1000",
"gene_ontology": "GO:0005741; mitochondrial outer membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion nucleoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0269",
"definition": "The mitochondrial nucleoid is the mitochondrial pseudocompartment formed by the chromatin-dense area. This region, which is functionally equivalent to the eukaryotic nucleus, is not surrounded by a membrane. ",
"synonyms": "Mitochondrial nucleoid; Mitochromosome.; ",
"content": "Mitochondrion matrix, mitochondrion nucleoid.",
"is_a": null,
"part_of": "Mitochondrion matrix.; ",
"keyword": "KW-1135",
"gene_ontology": "GO:0042645; mitochondrial nucleoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0171",
"definition": "The membrane surrounding a mitochondrion. This term is used when it is not known if the protein is found in or associated with the inner or outer mitochondrial membrane. ",
"synonyms": "Mitochondrial membrane.; ",
"content": "Mitochondrion membrane.",
"is_a": "Membrane.; ",
"part_of": "Mitochondrion envelope.; ",
"keyword": null,
"gene_ontology": "GO:0031966; mitochondrial membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion matrix.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0170",
"definition": "The matrix of a mitochondrion is the mitochondrion internal spaces enclosed by the inner membrane. Several of the steps in cellular respiration occur in the matrix due to its high concentration of enzymes. ",
"synonyms": "Mitochondrial matrix.; ",
"content": "Mitochondrion matrix.",
"is_a": null,
"part_of": "Mitochondrion.; ",
"keyword": null,
"gene_ontology": "GO:0005759; mitochondrial matrix; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion intermembrane space.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0169",
"definition": "The mitochondrial intermembrane space is the space between inner and outer mitochondrial membrane. ",
"synonyms": "Mitochondrial intermembrane space; Mitochondrial periplasm;; Mitochondrial periplasmic space.; ",
"content": "Mitochondrion intermembrane space.",
"is_a": null,
"part_of": "Mitochondrion envelope.; ",
"keyword": null,
"gene_ontology": "GO:0005758; mitochondrial intermembrane space; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Mitochondrion envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0167",
"definition": "The mitochondrial envelope comprises the inner and outer mitochondrial membrane including the intermembrane space. ",
"synonyms": "Mitochondrial envelope.; ",
"content": "Mitochondrion envelope.",
"is_a": null,
"part_of": "Mitochondrion.; ",
"keyword": null,
"gene_ontology": "GO:0005740; mitochondrial envelope; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Midbody.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0469",
"definition": "The midbody is the central region of the thin intercellular cytoplasmic bridge formed between daughter cells during cytokinesis. It consists of tightly bundled antiparallel microtubules, which embrace a phase-dense circular structure, called midbody ring. At the final stage of cytokinesis, the intercellular bridge is cleaved, in a process termed abscission, and two daughter cells are formed. Following abscission, the residual midbody structure, known as the midbody remnant or midbody derivative, can have different fates depending on the cell type. It can be either released to the extracellular medium, degraded by autophagy or persists in the cytoplasm, showing asymmetric accumulation in the daughter cells. ",
"synonyms": "Midbody derivative; Midbody remnant.; ",
"content": "Midbody.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030496; midbody; ",
"annotation": "Some authors consider that Flemming body and Midbody are synonyms. This is not the case in UniProtKB, where we use Flemming body as a synonym for Midbody ring, a specific part of the midbody. If you have doubt, use the broader term, Midbody. ",
"references": null,
"links": null
},
{
"location_identifier": "Microvillus.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0293",
"definition": "Microvilli are thin cylindrical dynamic cell projections containing a core bundle of actin filaments. They serve a diverse set of functions, such as increasing absorptive surface area in the epithelial brush border, tethering leukocytes to the surface of endothelial cells or participate in sperm-oocyte fusion. ",
"synonyms": "Microvilli.; ",
"content": "Cell projection, microvillus.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005902; microvillus; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Microvillus membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0294",
"definition": "The portion of the cell membrane surrounding a microvillus. ",
"synonyms": "Microvillar membrane.; ",
"content": "Cell projection, microvillus membrane.",
"is_a": null,
"part_of": "Cell membrane.; Microvillus.; ",
"keyword": null,
"gene_ontology": "GO:0031528; microvillus membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Microsome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0165",
"definition": "The membrane surrounding the microsome. ",
"synonyms": "Microsomal membrane.; ",
"content": "Microsome membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Microsome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Extracellular vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0499",
"definition": "Extracellular vesicles are vesicles that have been released by cells. ",
"synonyms": "Microparticle.; ",
"content": "Extracellular vesicle.",
"is_a": "Vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": "PubMed=24769233; DOI=10.1016/j.jprot.2014.04.028;; ",
"links": null
},
{
"location_identifier": "Microneme membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0164",
"definition": "The membrane surrounding a microneme. ",
"synonyms": "Micronemal membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, microneme membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Microneme.; ",
"keyword": null,
"gene_ontology": "GO:0033163; microneme membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Microneme lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0339",
"definition": "The micronemal compartment bounded by the membrane of a microneme. ",
"synonyms": "Micronemal lumen.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, microneme lumen.",
"is_a": "Secretory vesicle lumen.; ",
"part_of": "Microneme.; ",
"keyword": null,
"gene_ontology": "GO:0034494; microneme lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Bacterial microcompartment.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0544",
"definition": "Bacterial microcompartments (BMC) are proteinaceous polyhedral shells that encapsulate enzymes. The selectively permeable organelles protect their contents from the cytoplasm and/or the cytoplasm from reactants in their interior. The best characterized BMC is the carboxysome, which encapsulates RuBisCO and carbonic anhydrase, and enhances autotrophic CO(2) fixation. Other characterized BMCs encapsulate enzymes involved in ethanolamine or propanediol degradation; both pathways make toxic intermediates. Artifical BMCs can be expressed and filled with cargo proteins for biotechnological uses. BMCs are found in many bacterial phyla; in most cases their cargo is unknown. ",
"synonyms": "Metabolosome; Polyhedral organelle.; ",
"content": "Bacterial microcompartment.",
"is_a": null,
"part_of": null,
"keyword": "KW-1283",
"gene_ontology": "GO:0031469; bacterial microcompartment; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Melanosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0160",
"definition": "The membrane surrounding a melanosome. ",
"synonyms": "Melanosomal membrane.; ",
"content": "Melanosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Melanosome.; ",
"keyword": null,
"gene_ontology": "GO:0033162; melanosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Melanosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0338",
"definition": "The melanosomal compartment bounded by the membrane surrounding a melanosome. ",
"synonyms": "Melanosomal lumen.; ",
"content": "Melanosome lumen.",
"is_a": null,
"part_of": "Melanosome.; ",
"keyword": null,
"gene_ontology": "GO:0034493; melanosome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spindle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0251",
"definition": "The spindle is a specialized microtubule structure designed to attach and capture chromosomes in order to partition them evenly to each daughter cells. ",
"synonyms": "Meiotic spindle; Mitotic apparatus; Mitotic spindle.; ",
"content": "Cytoplasm, cytoskeleton, spindle.",
"is_a": null,
"part_of": "Cytoskeleton.; ",
"keyword": null,
"gene_ontology": "GO:0005819; spindle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "M line.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0315",
"definition": "In electron micrographs of the sarcomere, the M line appears as a series of parallel electron-dense lines in the central zone of the A band impliing that the M line is needed for the regular packing of the thick filaments. The M line maintains the myosin filaments in a hexagonal lattice. ",
"synonyms": "M band; M-band; M-line.; ",
"content": "Cytoplasm, myofibril, sarcomere, M line.",
"is_a": null,
"part_of": "H zone.; ",
"keyword": null,
"gene_ontology": "GO:0031430; M band; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
}
]
}