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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=60&ordering=-synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=20&ordering=-synonyms",
"results": [
{
"location_identifier": "Apical lamina.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0016",
"definition": "In the sea urchin embryos the apical lamina is a fibrous meshwork that remains after removal of hyalin from the hyalin layer. ",
"synonyms": null,
"content": "Secreted, extracellular space, extracellular matrix, apical lamina.",
"is_a": "Extracellular matrix.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0032579; apical lamina of hyaline layer; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Barrier septum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0454",
"definition": "The barrier septum, is a septum which spans a cell and does not allow exchange of organelles or cytoplasm between compartments. ",
"synonyms": null,
"content": "Barrier septum.",
"is_a": "Cell septum.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0000935; division septum; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cell surface.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0310",
"definition": "The outermost side of the cell. ",
"synonyms": null,
"content": "Cell surface.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009986; cell surface; ",
"annotation": "Try to use a child/narrower/more specific term instead ",
"references": null,
"links": null
},
{
"location_identifier": "Basement membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0025",
"definition": "The basement membrane is a highly specialized extracellular matrix structure undelying the basal surface of cells exhibiting polarity (epithelial, endothelial and mesothelial cells) and surrounding certain cell types such as muscle, adipose and Schwann cells. ",
"synonyms": null,
"content": "Secreted, extracellular space, extracellular matrix, basement membrane.",
"is_a": "Extracellular matrix.; ",
"part_of": null,
"keyword": "KW-0084",
"gene_ontology": "GO:0005604; basement membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Centrosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0048",
"definition": "The centrosome is a microtubule organizing center (MTOC) responsible for the nucleation and organisation of microtubules. It is composed of two orthogonally arranged centrioles, each one having a barrel shaped microtubule structure, and their surrounding pericentriolar material (PCM). ",
"synonyms": null,
"content": "Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.",
"is_a": null,
"part_of": "Microtubule organizing center.; ",
"keyword": null,
"gene_ontology": "GO:0005813; centrosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Bleb.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0472",
"definition": "These cellular membrane protrusions are the result of actomyosin contractions of the cortex, which cause either transient detachment of the cell membrane from the actin cortex or a rupture in the actin cortex. Then, cytosol streams out of the cell body and inflates the newly formed bleb. Once expansion slows, an actin cortex is reconstituted. Retraction is powered by myosin motor proteins. Blebbing is a common feature of cell physiology during cell movement, cytokinesis, cell spreading and apoptosis. ",
"synonyms": null,
"content": "Cell projection, bleb.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0032059; bleb; ",
"annotation": null,
"references": "PubMed=17318224; DOI=10.1038/nrm2122;; ",
"links": null
},
{
"location_identifier": "Apoplast.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0019",
"definition": "The apoplast is the \"non-living\" extracellular space that surrounds the symplast. It consists of cell walls and spaces between cells. Water and solutes can move freely in this framework, except at the endodermis in roots and stems where the apoplastic flow of ions is interrupted by the Casparian strip, forcing water to flow to symplast. ",
"synonyms": null,
"content": "Secreted, extracellular space, apoplast.",
"is_a": "Extracellular space.; ",
"part_of": null,
"keyword": "KW-0052",
"gene_ontology": "GO:0048046; apoplast; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPI-coated vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0076",
"definition": "The membrane surrounding a COPI-coated vesicle. COPI-coated vesicles mediate the vesicular transport of cargo such as proteins. COPI-coated vesicles are believed to bud from the cis-cisternae of the Golgi apparatus, mediate traffic from the cis-Golgi back to the ER (retrograde), and govern the flow pattern of materials within the Golgi stack. COPI is composed of the coatomer, which is a seven- subunit protein complex that participates in the formation of Golgi- derived coated vesicles. Evidence has also been presented for anterograde intra-Golgi transport mediated by COPI in yeast and mammals. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, COPI-coated vesicle membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "COPI-coated vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0030663; COPI-coated vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromaffin granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0061",
"definition": "A chromaffin granule is a specialized secretory vesicle characteristic of chromaffin cells. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, chromaffin granule.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0042583; chromaffin granule; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chlorosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0059",
"definition": "The chlorosome is a photosynthetic light-harvesting complex found in anoxygenic green bacteria. Chlorosomes are flattened ellipsoidal organelles appressed to the cytoplasmic face of the cell membrane. They typically contain highly aggregated bacteriochlorophyll c, d, or e (Bchl), a small amount of Bchl a, carotenoids, quinones, and occasionally wax esters. The chlorosome envelope of green sulfur bacteria is an asymmetric membrane containing galactolipids with the galactosyl moieties exposed on the outer surface. The farnesyl tails of the BChl molecules within the chlorosome probably comprise the inner leaflet of this membrane. ",
"synonyms": null,
"content": "Chlorosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-0151",
"gene_ontology": "GO:0046858; chlorosome; ",
"annotation": null,
"references": "PubMed=16866355; DOI=10.1021/bi060776y;; ",
"links": null
},
{
"location_identifier": "Ascus epiplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0538",
"definition": "Ascus cytoplasm that is not packaged into ascospores. ",
"synonyms": null,
"content": "Ascus epiplasm.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0072324; ascus epiplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated pit.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0069",
"definition": "Coated pits are regions of the cell membrane specialized in receptor- mediated endocytosis. Their cytoplasmic surface is coated with a bristlelike structure made of clathrin. During the first steps of endocytosis, clathrin-coated pits are internalized to form clathrin- coated vesicles which transport proteins from organelle to organelle. ",
"synonyms": null,
"content": "Membrane, clathrin-coated pit.",
"is_a": "Coated pit.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005905; clathrin-coated pit; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chloroplast thylakoid lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0057",
"definition": "The chloroplast thylakoid lumen is the chloroplast compartment bounded by the thylakoid membranes. ",
"synonyms": null,
"content": "Plastid, chloroplast thylakoid lumen.",
"is_a": "Plastid thylakoid lumen.; ",
"part_of": "Chloroplast thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0009543; chloroplast thylakoid lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytolytic granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0547",
"definition": "The cytolytic granule membrane is the membrane surrounding a cytolytic granule. ",
"synonyms": null,
"content": "Cytolytic granule membrane.",
"is_a": "Lysosome membrane.; ",
"part_of": "Cytolytic granule.; ",
"keyword": null,
"gene_ontology": "GO:0101004; cytolytic granule membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Capsule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0033",
"definition": "The capsule is a protective structure surrounding some bacteria or fungi. The bacterial capsule is a layer of material, usually polysaccharide, attached to the cell wall possibly via covalent attachments to either phospholipid or lipid-A molecules. It has several functions: promote bacterial adhesion to surfaces or interaction with other organisms; act as a permeability barrier, as a defense mechanism against phagocytosis and/or as a nutrient reserve. Among pathogens, capsule formation often correlates with pathogenicity. The fungal capsule is an extracellular layer which lies outside the cell wall and it is usually composed of polysaccharides. It protects the cell from different environmental dangers such as phagocytosis, dessication, etc. ",
"synonyms": null,
"content": "Secreted, capsule.",
"is_a": null,
"part_of": "Cell envelope.; Secreted.; ",
"keyword": null,
"gene_ontology": "GO:0042603; capsule; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Carboxysome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0034",
"definition": "Carboxysomes are bacterial microcompartments in which ribulose bisphosphate carboxylase (RuBisCO)-mediated CO(2) fixation occurs. The cytoplasmic polyhedral inclusion bodies are surrounded by a thin protein coat. They enhance autotrophic CO(2) fixation in air by increasing the CO(2) concentration around RuBisCO, thus reducing its reaction with O(2), a competing substrate. They contain carbonic anhydrase as part of the CO(2) concentration mechanism. ",
"synonyms": null,
"content": "Carboxysome.",
"is_a": "Bacterial microcompartment.; ",
"part_of": null,
"keyword": "KW-1282",
"gene_ontology": "GO:0031470; carboxysome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Coated pit.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0072",
"definition": "Coated pits are regions of the donor membrane where the assembly of the vesicle coat take place. The coat assembles from soluble protomers such as coat protein complex-I and coat protein complex-II. The components of the coat often define the intracellular sorting station, and contribute to both membrane deformation and local movement of the resulting transport intermediate following scission. During the first steps of the vesicle-mediated membrane transport, coated pits are internalized to form coated vesicles which transport proteins between distinct membrane-bound organelles. ",
"synonyms": null,
"content": "Membrane, coated pit.",
"is_a": null,
"part_of": "Endomembrane system.; ",
"keyword": "KW-0168",
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cell cortex.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0138",
"definition": "The cell cortex is the cytoplasmic region under the cell membrane. ",
"synonyms": null,
"content": "Cytoplasm, cell cortex.",
"is_a": null,
"part_of": "Cytoplasm.; ",
"keyword": null,
"gene_ontology": "GO:0005938; cell cortex; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Amyloplast.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0012",
"definition": "The amyloplast is a colorless plant plastid that forms and stores starch. Amyloplasts are found in many tissues, particularly in storage tissues. They are found in both photosynthetic and parasitic plants, i.e. even in plants that are not capable of photosynthesis. Many amyloplast proteins are also expressed in photosynthetic tissue. ",
"synonyms": null,
"content": "Plastid, amyloplast.",
"is_a": "Plastid.; ",
"part_of": null,
"keyword": "KW-0035",
"gene_ontology": "GO:0009501; amyloplast; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Dendrite.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0283",
"definition": "The dendrite is a short and typically branched process extending from the cell body of a neuron that receives and integrates signals coming from axons of other neurons, and conveys the resulting signal to the body of the cell. ",
"synonyms": null,
"content": "Cell projection, dendrite.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030425; dendrite; ",
"annotation": null,
"references": null,
"links": null
}
]
}