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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=420&ordering=synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=380&ordering=synonyms",
"results": [
{
"location_identifier": "Glyoxysome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0131",
"definition": "The glyoxysome is a plant peroxisome, especially found in germinating seeds, involved in the breakdown and conversion of fatty acids to acetyl-CoA for the glyoxylate bypass. Since it is also rich in catalase, the glyoxysome may be related to the microbodies or peroxisomes or derived from them. ",
"synonyms": null,
"content": "Glyoxysome.",
"is_a": "Peroxisome.; ",
"part_of": null,
"keyword": "KW-0330",
"gene_ontology": "GO:0009514; glyoxysome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Growth cone.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0288",
"definition": "The growth cone is a dynamic cell protrusion at the tip of the extending axon or dendrite. Neuron extends a specialized structure, the growth cone, to find targets in the wiring of the nervous system. The growth cone explores its environment by extending dynamic filopodia. Growth cone is composed of an ensemble of protruding and retracting veils (lamellipodia), net growth cone advance may be considered the vector sum of all veil's motility behavior in response to their local environments. Filopodia play a key role in delimiting veils and serving to nucleate the formation of new veils. ",
"synonyms": null,
"content": "Cell projection, growth cone.",
"is_a": "Neuron projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030426; growth cone; ",
"annotation": null,
"references": "PubMed=17327278; DOI=10.1242/jcs.03384;; ",
"links": null
},
{
"location_identifier": "Growth cone membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0289",
"definition": "The portion of the cell membrane surrounding a growth cone. ",
"synonyms": null,
"content": "Cell projection, growth cone membrane.",
"is_a": null,
"part_of": "Cell membrane.; Growth cone.; ",
"keyword": null,
"gene_ontology": "GO:0032584; growth cone membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Hemidesmosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0137",
"definition": "The hemidesmosome is an integrin-containing adhesive junction located along the basal layer of cells where they abut the basement membrane zone. As the name implies, only half the desmosome is present; only one cell is participating, the second cell being represented by the basement membrane. ",
"synonyms": null,
"content": "Cell junction, hemidesmosome.",
"is_a": "Cell junction.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030056; hemidesmosome; ",
"annotation": "Add \"Cell membrane\" if the protein is clearly associated with the membrane. ",
"references": null,
"links": "http://celljunctions.med.nyu.edu/hemidesmosomes/hemimain.html; "
},
{
"location_identifier": "Host.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0431",
"definition": "The host is any organism in which another organism, or symbiont, spends part or all of its life cycle. Most animals and plants live symbiotically with microorganisms. The larger organism is called the host and smaller organism the symbiont. When the interactions between the symbiont and the host benefits both partners, the symbiotic interaction is called mutualism. When there is a negative effect on one of the partners, it is called a parasitic symbiosis and if there is no beneficial or negative effect it is a commensal symbiosis. These clear-cut definitions are not always easy to apply in nature. Take the bacterium Pseudomonas aeruginosa for example. This bacterium can be found on the skin of humans and not cause disease, perhaps we would call it a commensial, but if the person has a severe burn P. aeruginosa can cause an infection and becomes a pathogen (a medicinal term for parasitism). This type of organism is called an opportunistic pathogen. Whether an association is a mutualist, commensal or parasitic depends on the relative \"strengths\" of the partners and the balance of power can change over time. ",
"synonyms": null,
"content": "Host.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0018995; host cellular component; ",
"annotation": null,
"references": null,
"links": "http://web.uconn.edu/mcbstaff/graf/GenSym/GenSym.htm; "
},
{
"location_identifier": "Host cell.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0427",
"definition": "A cell within a host organism including the host cell membrane and any external encapsulating structures such as the host cell wall and cell envelope. ",
"synonyms": null,
"content": "Host cell.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0043657; host cell; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell junction.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0374",
"definition": "The host cell junction is a host cell-host cell or host cell-host extracellular matrix contact within a tissue of a host multicellular organism, especially abundant in host epithelia. In vertebrates, there are three major types of cell junctions: anchoring junctions (e.g. adherens junctions), communicating junctions (e.g. gap junctions) and occluding junctions (e.g. tight junctions). ",
"synonyms": null,
"content": "Host cell junction.",
"is_a": null,
"part_of": "Host.; ",
"keyword": "KW-1031",
"gene_ontology": "GO:0044156; host cell junction; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell surface.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0378",
"definition": "The outermost side of the host cell. ",
"synonyms": null,
"content": "Host cell surface.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": null,
"gene_ontology": "GO:0044228; host cell surface; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cell wall.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0424",
"definition": "The complex and rigid layer surrounding the host cell. Host cell walls are found in bacteria, archaea, fungi, plants, and algae. The host cell wall is surrounded by an outer membrane in Gram-negative host bacteria, and envelopes the inner or plasma host membrane all host bacteria. It plays a role in host cell shape, cell stability and development, and protection against environmental dangers. ",
"synonyms": null,
"content": "Host cell wall.",
"is_a": null,
"part_of": "Host cell envelope.; ",
"keyword": null,
"gene_ontology": "GO:0044158; host cell wall; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cellular thylakoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0429",
"definition": "The host cellular thylakoids are formed usually by extensive invaginations of the host cyanobacterial cell membrane. In Synechocystis sp. strain PCC 6803, the thylakoid membranes are physically discontinuous from the plasma membrane, and thus represent bona fide intracellular organelles. ",
"synonyms": null,
"content": "Host cellular thylakoid.",
"is_a": "Host thylakoid.; ",
"part_of": "Host cell.; ",
"keyword": null,
"gene_ontology": "GO:0044159; host thylakoid; ",
"annotation": "Use only in cyanobacteria, not eukaryotes ",
"references": null,
"links": null
},
{
"location_identifier": "Host cellular thylakoid membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0430",
"definition": "The membrane of the host cyanobacterial cellular thylakoid. ",
"synonyms": null,
"content": "Host cellular thylakoid membrane.",
"is_a": "Host membrane.; ",
"part_of": "Host endomembrane system.; Host cellular thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0044160; host thylakoid membrane; ",
"annotation": "Use only in cyanobacteria, not eukaryotes ",
"references": null,
"links": null
},
{
"location_identifier": "Host cytoplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0381",
"definition": "The host cytoplasm is the content of a host cell within the plasma membrane and, in eukaryotics cells, surrounds the host nucleus. ",
"synonyms": null,
"content": "Host cytoplasm.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1035",
"gene_ontology": "GO:0030430; host cell cytoplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cytoplasmic vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0386",
"definition": "The host cytoplasmic vesicles mediate vesicular transport among the organelles of host secretory and endocytic systems. ",
"synonyms": null,
"content": "Host cytoplasmic vesicle.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1036",
"gene_ontology": "GO:0044161; host cell cytoplasmic vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cytoplasmic vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0387",
"definition": "The membrane surrounding a host cytoplasmic vesicle. These vesicles mediate vesicular transport among the organelles of secretory and endocytic systems. ",
"synonyms": null,
"content": "Host cytoplasmic vesicle membrane.",
"is_a": "Host membrane.; ",
"part_of": "Host cytoplasmic vesicle.; Host endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0044162; host cell cytoplasmic vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cytoskeleton.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0383",
"definition": "The host cytoskeleton is a dynamic three-dimensional structure that fills the host cytoplasm of eukaryotic cells. It is responsible for cell movement, cytokinesis, and the organization of the organelles or organelle-like structures within the host cell. ",
"synonyms": null,
"content": "Host cytoplasm, host cytoskeleton.",
"is_a": null,
"part_of": "Host cytoplasm.; ",
"keyword": "KW-1037",
"gene_ontology": "GO:0044163; host cytoskeleton; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host cytosol.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0384",
"definition": "The host cytosol is the unstructured aqueous phase of the host cytoplasm excluding organelles, membranes, and insoluble cytoskeletal components. ",
"synonyms": null,
"content": "Host cytoplasm, host cytosol.",
"is_a": null,
"part_of": "Host cytoplasm.; ",
"keyword": null,
"gene_ontology": "GO:0044164; host cell cytosol; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host early endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0461",
"definition": "The host early endosomes form a tubulovesicular network spread throughout the cortical cytoplasm of the host cell. Host early endosomes are the primary sorting station in the endocytic pathway from which endocytosed molecules can be recycled back to the host cell membrane or targeted to degradation in the host lysosomes. ",
"synonyms": null,
"content": "Host early endosome.",
"is_a": null,
"part_of": "Host endosome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host endoplasmic reticulum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0388",
"definition": "The host endoplasmic reticulum (ER) is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic host cell, especially those responsible for the production of hormones and other secretory products. ",
"synonyms": null,
"content": "Host endoplasmic reticulum.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1038",
"gene_ontology": "GO:0044165; host cell endoplasmic reticulum; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host endoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0389",
"definition": "The lumen of the host endoplasmic reticulum (ER) is the area enclosed by the host endoplasmic reticulum membrane, an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products. ",
"synonyms": null,
"content": "Host endoplasmic reticulum lumen.",
"is_a": null,
"part_of": "Host endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0044166; host cell endoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0390",
"definition": "The membrane surrounding the host endoplasmic reticulum (ER). The host endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic host cell, especially those responsible for the production of hormones and other secretory products. ",
"synonyms": null,
"content": "Host endoplasmic reticulum membrane.",
"is_a": "Host membrane.; ",
"part_of": "Host endoplasmic reticulum.; Host endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0044167; host cell endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
}
]
}