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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=440&ordering=synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=400&ordering=synonyms",
"results": [
{
"location_identifier": "Host endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0393",
"definition": "Host endosomes are highly dynamic membrane systems involved in transport within the host cell, they receive endocytosed host cell membrane molecules and sort them for either degradation or recycling back to the host cell surface. They also receive newly synthesised proteins destined for host vacuolar/lysosomal compartments. ",
"synonyms": null,
"content": "Host endosome.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1039",
"gene_ontology": "GO:0044174; host cell endosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host glyoxysome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0474",
"definition": "The host glyoxysome is a plant peroxisome, especially found in germinating seeds, involved in the breakdown and conversion of fatty acids to acetyl-CoA for the glyoxylate bypass. Since it is also rich in catalase, the glyoxysome may be related to the microbodies or peroxisomes or derived from them. ",
"synonyms": null,
"content": "Host glyoxysome.",
"is_a": "Host peroxisome.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host late endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0399",
"definition": "Host late endosomes are pleiomorphic with cisternal, tubular and multivesicular regions. They are found in juxtanuclear regions and concentrated at the host microtubule organizing center. They are an important sorting station in the endocytic pathway. Recycling to the plasma membrane and to the Golgi occurs in late endosomes. ",
"synonyms": null,
"content": "Host late endosome.",
"is_a": null,
"part_of": "Host endosome.; ",
"keyword": null,
"gene_ontology": "GO:0044184; host cell late endosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host lysosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0403",
"definition": "The host lysosome is a membrane-limited organelle present in all eukaryotic cells, which contains a large number of hydrolytic enzymes that are used for degrading almost any kind of cellular constituent, including entire organelles. The mechanisms responsible for delivering cytoplasmic cargo to the host lysosome/vacuole are known collectively as autophagy and play an important role in the maintenance of homeostasis. ",
"synonyms": null,
"content": "Host lysosome.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1042",
"gene_ontology": "GO:0044187; host cell lysosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0380",
"definition": "A host membrane is a lipid bilayer which surrounds host enclosed spaces and compartments. This selectively permeable structure is essential for effective separation of a host cell or organelle from its surroundings. ",
"synonyms": null,
"content": "Host membrane.",
"is_a": "Membrane.; ",
"part_of": null,
"keyword": "KW-1043",
"gene_ontology": "GO:0033644; host cell membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host microsome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0405",
"definition": "The host microsomes are a heterogenous set of vesicles 20-200nm in diameter and formed from the host endoplasmic reticulum when host cells are disrupted. ",
"synonyms": null,
"content": "Host microsome.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1044",
"gene_ontology": "GO:0033648; host intracellular membrane-bounded organelle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host mitochondrion.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0407",
"definition": "The host mitochondrion is a semiautonomous, self-reproducing organelle that occurs in the cytoplasm of all cells of most, but not all, host eukaryotes. Each host mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. They are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. ",
"synonyms": null,
"content": "Host mitochondrion.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1045",
"gene_ontology": "GO:0033650; host cell mitochondrion; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host nucleus.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0414",
"definition": "The host nucleus is the most obvious organelle in any host eukaryotic cell. It is a membrane-bound organelle and is surrounded by double membranes. It communicates with the surrounding cytosol via numerous nuclear pores. ",
"synonyms": null,
"content": "Host nucleus.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1048",
"gene_ontology": "GO:0042025; host cell nucleus; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host peroxisome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0475",
"definition": "The host peroxisome is a small eukaryotic organelle limited by a single membrane, specialized for carrying out oxidative reactions. Contains mainly peroxidases, several other oxidases and catalase. The catalase regulates the contents of the produced toxic hydrogen peroxide thus protecting the cell. Beta-oxidation of fatty acids is another major function of peroxisomes. In plants and fungi this degradation occurs only in this cellular compartment. ",
"synonyms": null,
"content": "Host peroxisome.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0120149; host cell peroxisome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host rough endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0423",
"definition": "The membrane surrounding the host rough endoplasmic reticulum. ",
"synonyms": null,
"content": "Host rough endoplasmic reticulum membrane.",
"is_a": "Host endoplasmic reticulum membrane.; ",
"part_of": "Host rough endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0044169; host cell rough endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host secretory vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0504",
"definition": "The host secretory vesicle is a host vesicle that mediates the vesicular transport of cargo - e.g. hormones or neurotransmitters - from an organelle to specific sites at the host cell membrane, where it docks and fuses to release its content. ",
"synonyms": null,
"content": "Host cytoplasmic vesicle, host secretory vesicle.",
"is_a": "Host cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host smooth endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0445",
"definition": "The membrane surrounding the host smooth endoplasmic reticulum. ",
"synonyms": null,
"content": "Host smooth endoplasmic reticulum membrane.",
"is_a": "Host endoplasmic reticulum membrane.; ",
"part_of": "Host rough endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0044171; host cell smooth endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host synapse.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0435",
"definition": "Host synapses are the communicating cell-cell junctions that allow signals to pass from a host nerve cell to a target cell. In a chemical synapse, the signal is carried by a neurotransmitter which diffuses across a narrow synaptic cleft and activates a receptor on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, neuronal axon, a specialized region of a muscle or a secretory cell. In an electrical synapse, a direct connection is made between the cytoplasms of two cells via gap junctions. ",
"synonyms": null,
"content": "Host synapse.",
"is_a": null,
"part_of": null,
"keyword": "KW-1051",
"gene_ontology": "GO:0044221; host cell synapse; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host synaptic vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0502",
"definition": "In a host synapse, host synaptic vesicles mediate the exocytosis of neurotransmitters and subsequent re-uptake by endocytosis of vesicular components. Re-uptake is a crucial element in the maintenance of host synaptic transmission in the nervous system. ",
"synonyms": null,
"content": "Host secretory vesicle, host synaptic vesicle.",
"is_a": "Host secretory vesicle.; ",
"part_of": "Host synapse.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host thylakoid.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0449",
"definition": "The host thylakoid is a membranous cellular structure containing the photosynthetic pigments, reaction centers and electron-transport chain. In host chloroplast, thylakoids stack up to form the grana or stay as single cisternae and interconnect the grana. Thylakoid, where photosynthesis occurs, are found in chloroplasts, cyanelles and in photosynthetic bacteria where they are the extensive invaginations of the plasma membrane. ",
"synonyms": null,
"content": "Host thylakoid.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": "KW-1050",
"gene_ontology": "GO:0044159; host thylakoid; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Host vacuole.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0506",
"definition": "The host vacuole is a fluid-filled, membrane-bound compartment in the cytoplasm. The precise form and function of vacuoles may vary between phyla. They are employed for a variety of purposes, including storage, as a degradative compartment, cell size control, secretion and following phagocytosis. ",
"synonyms": null,
"content": "Host vacuole.",
"is_a": null,
"part_of": "Host cell.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Hyaline layer.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0143",
"definition": "The hyaline layer is a multilayered extracellular matrix that coats the external surfaces of sea urchin and starfish embryos. ",
"synonyms": null,
"content": "Secreted, extracellular space, extracellular matrix, hyaline layer.",
"is_a": "Extracellular matrix.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0033166; hyaline layer; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Hydrogenosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0145",
"definition": "The hydrogenosome is a redox organelle of anaerobic unicellular eukaryotes which contains hydrogenase and produces hydrogen and ATP by glycolysis. They are found in various unrelated eukaryotes, such as anaerobic flagellates, chytridiomycete fungi and ciliates. Most hydrogenosomes lack a genome, but some like that of the anaerobic ciliate Nyctotherus ovalis, have retained a rudimentary genome. ",
"synonyms": null,
"content": "Hydrogenosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-0377",
"gene_ontology": "GO:0042566; hydrogenosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Invadopodium membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0290",
"definition": "The portion of the cell membrane surrounding an invadopodium. ",
"synonyms": null,
"content": "Cell projection, invadopodium membrane.",
"is_a": null,
"part_of": "Cell membrane.; Invadopodium.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Kinetochore.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0149",
"definition": "The kinetochore is a protein complex assembled on the centromeric region of DNA. It provides the major attachment point for the spindle microtubules during mitotic or meiotic division to pull the chromosomes apart. In monocentric chromosomes, the kinetochores of point centromeres bind a single microtubule and the larger kinetochores of regional centromeres interact with a number of microtubules. In holocentric chromosomes, the kinetochores bind the diffuse centromere along the length of the chromosomes. ",
"synonyms": null,
"content": "Chromosome, centromere, kinetochore.",
"is_a": null,
"part_of": "Centromere.; ",
"keyword": "KW-0995",
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
}
]
}