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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=460&ordering=-location_identifier",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=420&ordering=-location_identifier",
"results": [
{
"location_identifier": "Clathrin-coated vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0319",
"definition": "The clathrin-coated vesicle compartment bounded by the clathrin-coated vesicle membrane. ",
"synonyms": "Clathrin-coated vesicular lumen.; ",
"content": "Cytoplasmic vesicle, clathrin-coated vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Clathrin-coated vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0070",
"definition": "Clathrin coated vesicles (CCVs) mediate the vesicular transport of cargo such as proteins between organelles in the post-Golgi network connecting the trans-Golgi network, endosomes, lysosomes and the cell membrane. CCVs that bud from the cell membrane reveal a striking polyhedral pattern reminiscent of a fullerene which arises from the outermost protein in the coat, clathrin. Clathrin assembles from three-legged individual components called triskelions to form a polygonal lattice around the vesicle. Clathrin is a large heterohexameric protein complex composed of three heavy chains and three light chains. Clathrin molecules self-assemble together to make a spherical clathrin lattice structure, a polyhedron made of regular pentagons and hexagons. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. The connection of the clathrin scaffold to the membrane is mediated by clathrin adaptors, which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes. Clathrin-associated adaptor protein (AP) complexes are a stoichiometric coat component of CCVs alongside clathrin itself, and are considered a major clathrin adaptor contributing the CCV formation. ",
"synonyms": "CCV.; ",
"content": "Cytoplasmic vesicle, clathrin-coated vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030136; clathrin-coated vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated pit.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0069",
"definition": "Coated pits are regions of the cell membrane specialized in receptor- mediated endocytosis. Their cytoplasmic surface is coated with a bristlelike structure made of clathrin. During the first steps of endocytosis, clathrin-coated pits are internalized to form clathrin- coated vesicles which transport proteins from organelle to organelle. ",
"synonyms": null,
"content": "Membrane, clathrin-coated pit.",
"is_a": "Coated pit.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005905; clathrin-coated pit; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "cis-Golgi network membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0068",
"definition": "The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. ",
"synonyms": "CGN membrane; cis-Golgi complex membrane; cis-Golgi membrane;; Golgi cis-face membrane.; ",
"content": "Golgi apparatus, cis-Golgi network membrane.",
"is_a": "Golgi apparatus membrane.; ",
"part_of": "cis-Golgi network.; ",
"keyword": null,
"gene_ontology": "GO:0033106; cis-Golgi network membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "cis-Golgi network.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0067",
"definition": "The cis-Golgi network is an extensive tubulovesicular network bound to the cis face of the Golgi stack and which function is to receive process the biosynthetic output from the ER. ",
"synonyms": "CGN; cis-Golgi; cis-Golgi complex; Golgi cis-face.; ",
"content": "Golgi apparatus, cis-Golgi network.",
"is_a": null,
"part_of": "Golgi apparatus.; ",
"keyword": null,
"gene_ontology": "GO:0005801; cis-Golgi network; ",
"annotation": "The CGN is not the cis cisternae of the Golgi stack. Compartment specific marker: GOLGA2/GM130. ",
"references": null,
"links": null
},
{
"location_identifier": "Cilium membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0305",
"definition": "The portion of the cell membrane surrounding the cilium. ",
"synonyms": "Ciliary membrane.; ",
"content": "Cell projection, cilium membrane.",
"is_a": null,
"part_of": "Cell membrane.; Cilium.; ",
"keyword": null,
"gene_ontology": "GO:0060170; ciliary membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cilium basal body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0087",
"definition": "The basal body is a barrel-shaped microtubule-based structure required for the formation of cilia. Basal bodies, structuraly related to and often interconvertible with centrioles, serves as a nucleation site for axoneme growth. ",
"synonyms": "Ciliary basal body; Ciliary kinetosome; Cilium kinetosome.; ",
"content": "Cytoplasm, cytoskeleton, cilium basal body.",
"is_a": null,
"part_of": "Cilium.; Cytoskeleton.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cilium axoneme.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0304",
"definition": "The cilium axoneme is the most prominent structural component of the cilium. It consists of nine doublet microtubules, with all motile cilia - except those at the embryonic node - containing an additional central pair of microtubules. The axonemal microtubules of all cilia nucleate and extend from a basal body, a centriolar structure most often composed of a radial array of nine triplet microtubules. In most cells, basal bodies associate with cell membranes and cilia are assembled as 'extracellular' membrane-enclosed compartments. ",
"synonyms": "Ciliary axoneme.; ",
"content": "Cytoplasm, cytoskeleton, cilium axoneme.",
"is_a": null,
"part_of": "Cilium.; Cytoskeleton.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cilium.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0066",
"definition": "The cilium is a cell surface projection found at the surface of a large proportion of eukaryotic cells. The two basic types of cilia, motile (alternatively named flagella) and non-motile, collectively perform a wide variety of functions broadly encompassing cell/fluid movement and sensory perception. Their most prominent structural component is the axoneme which consists of nine doublet microtubules, with all motile cilia - except those at the embryonic node - containing an additional central pair of microtubules. The axonemal microtubules of all cilia nucleate and extend from a basal body, a centriolar structure most often composed of a radial array of nine triplet microtubules. In most cells, basal bodies associate with cell membranes and cilia are assembled as 'extracellular' membrane-enclosed compartments. ",
"synonyms": "Cilia.; ",
"content": "Cell projection, cilium.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005929; cilium; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0468",
"definition": "An organized structure composed of a single very long molecule of coiled DNA and associated proteins (e.g. histones) that carries hereditary information. ",
"synonyms": "Chromoplastic stroma.; ",
"content": "Chromosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-0158",
"gene_ontology": "GO:0005694; chromosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast stroma.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0065",
"definition": "The chromoplast stroma is the space enclosed by the chromoplast double membrane but excluding the photosynthetic material. The chromoplast is a plastid containing pigments other than chlorophyll. ",
"synonyms": "Chromoplastic stroma.; ",
"content": "Plastid, chromoplast stroma.",
"is_a": null,
"part_of": "Chromoplast.; ",
"keyword": null,
"gene_ontology": "GO:0009575; chromoplast stroma; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0064",
"definition": "The membrane surrounding the chromoplast. Also used when it is not clear in which chromoplast membrane (outer membrane, inner membrane or thylakoid) a protein is found. ",
"synonyms": "Chromoplastic membrane.; ",
"content": "Plastid, chromoplast membrane.",
"is_a": "Plastid membrane.; ",
"part_of": "Chromoplast.; ",
"keyword": null,
"gene_ontology": "GO:0046862; chromoplast membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0063",
"definition": "A chromoplast is a plastid containing pigments other than chlorophyll. Found in flower, petals and fruit. ",
"synonyms": null,
"content": "Plastid, chromoplast.",
"is_a": "Plastid.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009509; chromoplast; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromaffin granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0062",
"definition": "The chromaffin granule membrane is the membrane surrounding a chromaffin granule, a specialized secretory vesicle characteristic of chromaffin cells. ",
"synonyms": "Chromaffin granular membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Chromaffin granule.; ",
"keyword": null,
"gene_ontology": "GO:0042584; chromaffin granule membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromaffin granule lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0349",
"definition": "The chromaffin granule comparment bounded by the chromaffin granule membrane. ",
"synonyms": "Chromaffin granular lumen.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen.",
"is_a": "Secretory vesicle lumen.; ",
"part_of": "Chromaffin granule.; ",
"keyword": null,
"gene_ontology": "GO:0034466; chromaffin granule lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromaffin granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0061",
"definition": "A chromaffin granule is a specialized secretory vesicle characteristic of chromaffin cells. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, chromaffin granule.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0042583; chromaffin granule; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chlorosome envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0060",
"definition": "The chlorosome envelope of green sulfur bacteria is an asymmetric membrane containing galactolipids with the galactosyl moieties exposed on the outer surface. The farnesyl tails of the BChl c molecules within the chlorosome probably comprise the inner leaflet of this membrane. ",
"synonyms": "Chlorosomal envelope.; ",
"content": "Chlorosome, chlorosome envelope.",
"is_a": null,
"part_of": "Chlorosome.; ",
"keyword": null,
"gene_ontology": "GO:0033105; chlorosome envelope; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chlorosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0059",
"definition": "The chlorosome is a photosynthetic light-harvesting complex found in anoxygenic green bacteria. Chlorosomes are flattened ellipsoidal organelles appressed to the cytoplasmic face of the cell membrane. They typically contain highly aggregated bacteriochlorophyll c, d, or e (Bchl), a small amount of Bchl a, carotenoids, quinones, and occasionally wax esters. The chlorosome envelope of green sulfur bacteria is an asymmetric membrane containing galactolipids with the galactosyl moieties exposed on the outer surface. The farnesyl tails of the BChl molecules within the chlorosome probably comprise the inner leaflet of this membrane. ",
"synonyms": null,
"content": "Chlorosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-0151",
"gene_ontology": "GO:0046858; chlorosome; ",
"annotation": null,
"references": "PubMed=16866355; DOI=10.1021/bi060776y;; ",
"links": null
},
{
"location_identifier": "Chloroplast thylakoid membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0058",
"definition": "The thylakoid membranes of a chloroplast is an internal system of interconnected membranes, that carry out the light reactions of photosynthesis. They are arranged into stacked and unstacked regions called grana and stroma thylakoids, respectively, that are differentially enriched in photosystem I and II complexes. Although extensive, the thylakoid network in an individual chloroplast is thought to comprise a single lumenal compartment. ",
"synonyms": null,
"content": "Plastid, chloroplast thylakoid membrane.",
"is_a": "Plastid thylakoid membrane.; ",
"part_of": "Chloroplast thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0009535; chloroplast thylakoid membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chloroplast thylakoid lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0057",
"definition": "The chloroplast thylakoid lumen is the chloroplast compartment bounded by the thylakoid membranes. ",
"synonyms": null,
"content": "Plastid, chloroplast thylakoid lumen.",
"is_a": "Plastid thylakoid lumen.; ",
"part_of": "Chloroplast thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0009543; chloroplast thylakoid lumen; ",
"annotation": null,
"references": null,
"links": null
}
]
}