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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=520&ordering=synonyms",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=480&ordering=synonyms",
"results": [
{
"location_identifier": "Rough endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0237",
"definition": "The membrane surrounding the rough endoplasmic reticulum. ",
"synonyms": null,
"content": "Rough endoplasmic reticulum membrane.",
"is_a": "Endoplasmic reticulum membrane.; ",
"part_of": "Rough endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0030867; rough endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Ruffle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0300",
"definition": "A ruffle is a cell protrusion at the leading edge of a crawling cell. Ruffles are supported by a microfilament meshwork. ",
"synonyms": null,
"content": "Cell projection, ruffle.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0001726; ruffle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Ruffle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0301",
"definition": "The portion of the cell membrane surrounding a ruffle. ",
"synonyms": null,
"content": "Cell projection, ruffle membrane.",
"is_a": null,
"part_of": "Cell membrane.; Ruffle.; ",
"keyword": null,
"gene_ontology": "GO:0032587; ruffle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "S-layer.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0262",
"definition": "The S-layer is a paracrystalline protein thin layer attached to the outermost portion of the cell wall. Found in some bacteria and common in archaea where it can constitute the only cell wall structure outside the plasma membrane. In Gram-negative bacteria, the S-layer is directly attached to the outer membrane. In Gram-positive bacteria, the S-layer is attached to the peptidoglycan layer. The S-layer may protect the cell from aggressions such as phagocytosis, harmful enzymes, etc. It also allows bacteria to adhere to host cells or other environmental surfaces and to maintain shape and envelope rigidity. ",
"synonyms": null,
"content": "Secreted, cell wall, S-layer.",
"is_a": null,
"part_of": "Cell wall.; ",
"keyword": "KW-0701",
"gene_ontology": "GO:0030115; S-layer; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcomere.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0313",
"definition": "The sarcomere represents the basal contractile unit of striated muscles. A single myofibril is composed of these short structural units arranged end to end, which contract due to the relative sliding of thick (myosin) over thin (actin) filaments. The mammalian sarcomere is ~ 2 mm in length, and can shorten to ~ 70% of its original length during contraction. Structural features of the sarcomere include bundles of parallel thick and thin filaments assembled by two transverse structures, the Z lines and M lines. The Z lines and the M lines are connected by transverse filaments to the sarcolemma or to the neighboring myofibrils. Sarcomeres give to skeletal and cardiac muscles their striated appearance with I bands surrounding the Z lines, followed by A bands. The A bands contain a paler region called the H zone and in the middle the M line. ",
"synonyms": null,
"content": "Cytoplasm, myofibril, sarcomere.",
"is_a": null,
"part_of": "Myofibril.; ",
"keyword": null,
"gene_ontology": "GO:0030017; sarcomere; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
},
{
"location_identifier": "Sarcoplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0311",
"definition": "The sarcoplasm is the cytoplasm of a muscle fiber or muscle cell or myofiber. ",
"synonyms": null,
"content": "Cytoplasm, sarcoplasm.",
"is_a": "Cytoplasm.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0016528; sarcoplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0239",
"definition": "The sarcoplasmic reticulum (SR) is a highly specialized form of the smooth endoplasmic reticulum which is dedicated to the regulation of intracellular calcium homeostasis. The SR can be subdivided in at least two well-characterized regions: the terminal cisternae, where the calcium ions are released, and the longitudinal tubules specialized in the uptake of the calcium ions. ",
"synonyms": null,
"content": "Sarcoplasmic reticulum.",
"is_a": null,
"part_of": null,
"keyword": "KW-0703",
"gene_ontology": "GO:0016529; sarcoplasmic reticulum; ",
"annotation": "Not ok: HI Endoplasmic reticulum. ",
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0240",
"definition": "The lumen of the sarcoplasmic reticulum is the area enclosed by the sarcoplasmic reticulum membrane. ",
"synonyms": null,
"content": "Sarcoplasmic reticulum lumen.",
"is_a": null,
"part_of": "Sarcoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0033018; sarcoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0241",
"definition": "The membrane surrounding the sarcoplasmic reticulum (SR). ",
"synonyms": null,
"content": "Sarcoplasmic reticulum membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Sarcoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0033017; sarcoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Secondary cell wall.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0242",
"definition": "In some plants, and cell types after a maximum size or point in development has been reached, a secondary wall, often layered, is constructed below the primary wall. Unlike the primary wall, it losts plasticity and is made usually of cellulose, hemicellulose and lignin. ",
"synonyms": null,
"content": "Secreted, secondary cell wall.",
"is_a": "Cell wall.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009531; secondary cell wall; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Secreted.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0243",
"definition": "Protein located outside the cell membrane(s). ",
"synonyms": null,
"content": "Secreted.",
"is_a": null,
"part_of": null,
"keyword": "KW-0964",
"gene_ontology": "GO:0005576; extracellular region; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Slime layer.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0247",
"definition": "The slime layer is an easily removed, diffuse, unorganized layer of extracellular material which surrounds the bacterial cell. It is usually composed of polysaccharides and it may serve to trap nutrients, to aid in cell motility, to bind cells together or to adhere to smooth surfaces. Slime layers are a more-diffuse glycocalyx than capsules. ",
"synonyms": null,
"content": "Secreted, slime layer.",
"is_a": null,
"part_of": "Secreted.; ",
"keyword": null,
"gene_ontology": "GO:0030114; slime layer; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Smooth endoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0249",
"definition": "The smooth endoplasmic reticulum lumen is the area enclosed by the smooth endoplasmic reticulum membrane. ",
"synonyms": null,
"content": "Smooth endoplasmic reticulum lumen.",
"is_a": "Endoplasmic reticulum lumen.; ",
"part_of": "Smooth endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0048238; smooth endoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Smooth endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0250",
"definition": "The membrane surrounding the smooth endoplasmic reticulum. ",
"synonyms": null,
"content": "Smooth endoplasmic reticulum membrane.",
"is_a": "Endoplasmic reticulum membrane.; ",
"part_of": "Smooth endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0030868; smooth endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spindle pole.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0448",
"definition": "Either of the ends of a spindle, a specialized microtubule structure designed to attach and capture chromosomes in order to partition them evenly to each daughter cells. ",
"synonyms": null,
"content": "Cytoplasm, cytoskeleton, spindle pole.",
"is_a": null,
"part_of": "Spindle.; ",
"keyword": null,
"gene_ontology": "GO:0000922; spindle pole; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spine apparatus.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0530",
"definition": "Specialized form of endoplasmic reticulum found in a subpopulation of dendritic spines in central neurons consisting of two or more closely apposed lamellae with interspersed electron dense material. ",
"synonyms": null,
"content": "Endoplasmic reticulum, spine apparatus.",
"is_a": "Endoplasmic reticulum.; ",
"part_of": "Dendritic spine.; Postsynapse.; ",
"keyword": null,
"gene_ontology": "GO:0097444; spine apparatus; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spore coat.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0366",
"definition": "Protein found in the spore coat. The spore coat is the thick layer found beneath the perispore of some eukaryotic spores and bacterial mature spores. It is made up of highly cross-linked keratin and layers of specific proteins. The coat is composed of several electron-dense and lamella-like layers, differing between species. ",
"synonyms": null,
"content": "Spore coat.",
"is_a": null,
"part_of": "Spore.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spore core.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0253",
"definition": "Protein found in the spore core. The core also called spore matrix is the central part of the spore and contains normal cell structures, such as DNA, proteins and ribosomes, but is metabolically inactive. ",
"synonyms": null,
"content": "Spore core.",
"is_a": null,
"part_of": "Spore.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spore cortex.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0364",
"definition": "Protein found in the spore cortex. The spore cortex is a loosely cross-linked peptidoglycan layer localized between the spore core and the outer membrane or cortex membrane of bacterial mature spores. The cortex maintains heat resistance and dormancy. ",
"synonyms": null,
"content": "Spore cortex.",
"is_a": null,
"part_of": "Spore.; ",
"keyword": null,
"gene_ontology": "GO:0043595; endospore cortex; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spore outer membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0365",
"definition": "Protein associated with the spore outer membrane. The outer membrane, also called the cortex membrane, is a membrane localized between the cortex and the inner layer of the coat of bacterial mature spores. ",
"synonyms": null,
"content": "Spore outer membrane.",
"is_a": "Membrane.; ",
"part_of": "Spore.; ",
"keyword": null,
"gene_ontology": "GO:0043594; outer endospore membrane; ",
"annotation": null,
"references": null,
"links": null
}
]
}