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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=540",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=500",
"results": [
{
"location_identifier": "Synaptic cell membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0531",
"definition": "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. ",
"synonyms": null,
"content": "Synaptic cell membrane.",
"is_a": "Cell membrane.; ",
"part_of": "Synapse.; ",
"keyword": null,
"gene_ontology": "GO:0097060; synaptic membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Neuronal dense core vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0532",
"definition": "The membrane surrounding a neuronal dense core vesicle. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Neuronal dense core vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0099012; neuronal dense core vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Postsynaptic recycling endosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0533",
"definition": "The membrane surrounding a postsynaptic recycling endosome ",
"synonyms": null,
"content": "Postsynaptic recycling endosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Postsynaptic recycling endosome.; ",
"keyword": null,
"gene_ontology": "GO:0098944; postsynaptic recycling endosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Postsynaptic early endosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0534",
"definition": "The membrane surrounding a postsynaptic early endosome ",
"synonyms": null,
"content": "Postsynaptic early endosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Postsynaptic early endosome.; ",
"keyword": null,
"gene_ontology": "GO:0098896; postsynaptic early endosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Autolysosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0535",
"definition": "The autolysosome is a single-membrane organelle resulting from the fusion of a double-membrane autophagosome with a lysosome during macroautophagy. The outer membrane of the autophagosome fuses with the lysosome membrane whereas the inner membrane and the autophagic cargo are released into the lumen and degraded. Alternatively, the convergence of macroautophagy and endocytosis produces a single- membrane amphisome that also results in an autolysosome upon fusion with a lysosome. ",
"synonyms": "Degrading autophagic vacuole.; ",
"content": "Autolysosome.",
"is_a": "Autophagosome.; Lysosome.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0044754; autolysosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Autolysosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0536",
"definition": "The membrane surrounding the autolysosome. ",
"synonyms": null,
"content": "Autolysosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Autolysosome.; ",
"keyword": null,
"gene_ontology": "GO:0120281; autolysosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Autolysosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0537",
"definition": "The autolysosome lumen is the area enclosed by the autolysosomal membrane. ",
"synonyms": "Degrading autophagic vacuole lumen.; ",
"content": "Autolysosome lumen.",
"is_a": null,
"part_of": "Autolysosome.; ",
"keyword": null,
"gene_ontology": "GO:0120282; autolysosome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Ascus epiplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0538",
"definition": "Ascus cytoplasm that is not packaged into ascospores. ",
"synonyms": null,
"content": "Ascus epiplasm.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0072324; ascus epiplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Spore.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0539",
"definition": "Spores are hardy unicellular units used by various bacteria, fungi, plants and protozoa to allow them to remain dormant during long periods of time and under often unfavorable conditions. ",
"synonyms": "Ascospore; Basidiospore; Chlamydospore; Megaspore; Microspore;; Teliospore; Tetraspore; Zoospore.; ",
"content": "Spore.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Zona pellucida.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0540",
"definition": "Zona pellucida is a specialized extracellular matrix that surrounds the plasma membrane of mammalian oocytes. It is required for successful fertilization. Zona pellucida allows species-specific fertilization, prevents polyspermy, and enables acrosomal reaction for the successful adhesion and penetration of the sperm cell. ",
"synonyms": "Egg coat; Pellucid zone; Vitelline membrane.; ",
"content": "Zona pellucida.",
"is_a": null,
"part_of": "Extracellular matrix.; ",
"keyword": "KW-0272",
"gene_ontology": "GO:0035805; egg coat; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cortical granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0541",
"definition": "Cortical granules are secretory organelles located under the cell membrane of unfertilized oocytes. Following fertilization, cortical granules fuse with the oocyte's cell membrane and release their contents into the extracellular matrix. This exocytosis, known as the cortical reaction, is involved in the prevention of polyspermy. Cortical granules are found in all mammals and many other vertebrates, as well as some invertebrates. ",
"synonyms": "Cortical vesicle.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, Cortical granule.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0060473; cortical granule; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Dynein axonemal particle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0542",
"definition": "Dynein axonemal particles are ciliated cell-specific cytoplasmic membrane-less organelles, where dynein axonemal assembly factors (DNAAFs) and chaperones flux through rapidly while dynein subunits are stably retained. May act in storage or assembly of axonemal dyneins for rapid deployment to cilia. ",
"synonyms": "DynAP.; ",
"content": "Dynein axonemal particle.",
"is_a": null,
"part_of": "Cytoplasm.; ",
"keyword": null,
"gene_ontology": "GO:0120293; dynein axonemal particle; ",
"annotation": null,
"references": "PubMed=33263282; DOI=10.7554/elife.38497;; ",
"links": null
},
{
"location_identifier": "Cytolytic granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0543",
"definition": "A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. ",
"synonyms": "Lytic granule, cytotoxic granule.; ",
"content": "Cytolytic granule.",
"is_a": null,
"part_of": "Lysosome.; ",
"keyword": null,
"gene_ontology": "GO:0044194; cytolytic granule; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Bacterial microcompartment.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0544",
"definition": "Bacterial microcompartments (BMC) are proteinaceous polyhedral shells that encapsulate enzymes. The selectively permeable organelles protect their contents from the cytoplasm and/or the cytoplasm from reactants in their interior. The best characterized BMC is the carboxysome, which encapsulates RuBisCO and carbonic anhydrase, and enhances autotrophic CO(2) fixation. Other characterized BMCs encapsulate enzymes involved in ethanolamine or propanediol degradation; both pathways make toxic intermediates. Artifical BMCs can be expressed and filled with cargo proteins for biotechnological uses. BMCs are found in many bacterial phyla; in most cases their cargo is unknown. ",
"synonyms": "Metabolosome; Polyhedral organelle.; ",
"content": "Bacterial microcompartment.",
"is_a": null,
"part_of": null,
"keyword": "KW-1283",
"gene_ontology": "GO:0031469; bacterial microcompartment; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Zymogen granule.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0545",
"definition": "A membrane-bounded, cytoplasmic secretory granule found in enzyme- secreting cells that allows the sorting, packaging and regulated apical secretion of digestive enzymes. Enzymes are packaged in these granules as zymogen or proenzyme, their inactive precursor form. ",
"synonyms": null,
"content": "Zymogen granule.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0042588; zymogen granule; ",
"annotation": null,
"references": "PubMed=1191276; DOI=10.1016/0006-2944(75)90154-4;; ",
"links": null
},
{
"location_identifier": "Cytolytic granule lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0546",
"definition": "The cytolytic granule comparment bounded by the cytolytic granule membrane. ",
"synonyms": null,
"content": "Cytolytic granule lumen.",
"is_a": "Lysosome lumen.; ",
"part_of": "Cytolytic granule.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytolytic granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0547",
"definition": "The cytolytic granule membrane is the membrane surrounding a cytolytic granule. ",
"synonyms": null,
"content": "Cytolytic granule membrane.",
"is_a": "Lysosome membrane.; ",
"part_of": "Cytolytic granule.; ",
"keyword": null,
"gene_ontology": "GO:0101004; cytolytic granule membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Zymogen granule lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0548",
"definition": "The zymogen granule compartment bounded by the membrane of the secretory vesicle. ",
"synonyms": null,
"content": "Zymogen granule lumen.",
"is_a": "Secretory vesicle lumen.; ",
"part_of": "Zymogen granule.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Zymogen granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0549",
"definition": "The membrane surrounding zymogen granules. ",
"synonyms": null,
"content": "Zymogen granule membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Zymogen granule.; ",
"keyword": null,
"gene_ontology": "GO:0042589; zymogen granule membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Encapsulin nanocompartment.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0550",
"definition": "Proteinaceous polyhedral shells that encapsulate enzymes. The selectively permeable organelles protect their contents from their surrounding milieu and/or the milieu from reactants in their interior. The self-assembling, 25-42 nm nanocompartment shell, unlike larger bacterial microcompartments, is made of only 1 protein, and has only a few proteins inside. Shells 25 nm in diameter are made of 60 monomers, shells 32 nm are made of 180 monomers, while shells 42 nm in diameter are made of 240 monomers with T=1, T=3 or T=4 icosahedral symmetry respectively. The shell protein has an HK97-like fold and probably evolved from a viral protein. Artificial encapsulin nanocompartments can be expressed and filled with cargo proteins for biotechnological uses. They are found in many bacterial and a few archaeal phyla. In anammox bacteria they may be located inside the anammoxosome. ",
"synonyms": null,
"content": "Encapsulin nanocompartment.",
"is_a": null,
"part_of": null,
"keyword": "KW-1284",
"gene_ontology": "GO:0140737; encapsulin nanocompartment; ",
"annotation": null,
"references": null,
"links": null
}
]
}