HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=80",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=40",
"results": [
{
"location_identifier": "Chromaffin granule membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0062",
"definition": "The chromaffin granule membrane is the membrane surrounding a chromaffin granule, a specialized secretory vesicle characteristic of chromaffin cells. ",
"synonyms": "Chromaffin granular membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Chromaffin granule.; ",
"keyword": null,
"gene_ontology": "GO:0042584; chromaffin granule membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0063",
"definition": "A chromoplast is a plastid containing pigments other than chlorophyll. Found in flower, petals and fruit. ",
"synonyms": null,
"content": "Plastid, chromoplast.",
"is_a": "Plastid.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009509; chromoplast; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0064",
"definition": "The membrane surrounding the chromoplast. Also used when it is not clear in which chromoplast membrane (outer membrane, inner membrane or thylakoid) a protein is found. ",
"synonyms": "Chromoplastic membrane.; ",
"content": "Plastid, chromoplast membrane.",
"is_a": "Plastid membrane.; ",
"part_of": "Chromoplast.; ",
"keyword": null,
"gene_ontology": "GO:0046862; chromoplast membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Chromoplast stroma.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0065",
"definition": "The chromoplast stroma is the space enclosed by the chromoplast double membrane but excluding the photosynthetic material. The chromoplast is a plastid containing pigments other than chlorophyll. ",
"synonyms": "Chromoplastic stroma.; ",
"content": "Plastid, chromoplast stroma.",
"is_a": null,
"part_of": "Chromoplast.; ",
"keyword": null,
"gene_ontology": "GO:0009575; chromoplast stroma; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cilium.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0066",
"definition": "The cilium is a cell surface projection found at the surface of a large proportion of eukaryotic cells. The two basic types of cilia, motile (alternatively named flagella) and non-motile, collectively perform a wide variety of functions broadly encompassing cell/fluid movement and sensory perception. Their most prominent structural component is the axoneme which consists of nine doublet microtubules, with all motile cilia - except those at the embryonic node - containing an additional central pair of microtubules. The axonemal microtubules of all cilia nucleate and extend from a basal body, a centriolar structure most often composed of a radial array of nine triplet microtubules. In most cells, basal bodies associate with cell membranes and cilia are assembled as 'extracellular' membrane-enclosed compartments. ",
"synonyms": "Cilia.; ",
"content": "Cell projection, cilium.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005929; cilium; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "cis-Golgi network.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0067",
"definition": "The cis-Golgi network is an extensive tubulovesicular network bound to the cis face of the Golgi stack and which function is to receive process the biosynthetic output from the ER. ",
"synonyms": "CGN; cis-Golgi; cis-Golgi complex; Golgi cis-face.; ",
"content": "Golgi apparatus, cis-Golgi network.",
"is_a": null,
"part_of": "Golgi apparatus.; ",
"keyword": null,
"gene_ontology": "GO:0005801; cis-Golgi network; ",
"annotation": "The CGN is not the cis cisternae of the Golgi stack. Compartment specific marker: GOLGA2/GM130. ",
"references": null,
"links": null
},
{
"location_identifier": "cis-Golgi network membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0068",
"definition": "The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network. ",
"synonyms": "CGN membrane; cis-Golgi complex membrane; cis-Golgi membrane;; Golgi cis-face membrane.; ",
"content": "Golgi apparatus, cis-Golgi network membrane.",
"is_a": "Golgi apparatus membrane.; ",
"part_of": "cis-Golgi network.; ",
"keyword": null,
"gene_ontology": "GO:0033106; cis-Golgi network membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated pit.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0069",
"definition": "Coated pits are regions of the cell membrane specialized in receptor- mediated endocytosis. Their cytoplasmic surface is coated with a bristlelike structure made of clathrin. During the first steps of endocytosis, clathrin-coated pits are internalized to form clathrin- coated vesicles which transport proteins from organelle to organelle. ",
"synonyms": null,
"content": "Membrane, clathrin-coated pit.",
"is_a": "Coated pit.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005905; clathrin-coated pit; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0070",
"definition": "Clathrin coated vesicles (CCVs) mediate the vesicular transport of cargo such as proteins between organelles in the post-Golgi network connecting the trans-Golgi network, endosomes, lysosomes and the cell membrane. CCVs that bud from the cell membrane reveal a striking polyhedral pattern reminiscent of a fullerene which arises from the outermost protein in the coat, clathrin. Clathrin assembles from three-legged individual components called triskelions to form a polygonal lattice around the vesicle. Clathrin is a large heterohexameric protein complex composed of three heavy chains and three light chains. Clathrin molecules self-assemble together to make a spherical clathrin lattice structure, a polyhedron made of regular pentagons and hexagons. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. The connection of the clathrin scaffold to the membrane is mediated by clathrin adaptors, which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes. Clathrin-associated adaptor protein (AP) complexes are a stoichiometric coat component of CCVs alongside clathrin itself, and are considered a major clathrin adaptor contributing the CCV formation. ",
"synonyms": "CCV.; ",
"content": "Cytoplasmic vesicle, clathrin-coated vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030136; clathrin-coated vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Clathrin-coated vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0071",
"definition": "The membrane surrounding a clathrin-coated vesicle (CCV). CCVs mediate the vesicular transport of cargo such as proteins between organelles in the post-Golgi network connecting the trans-Golgi network, endosomes, lysosomes and the cell membrane. CCVs that bud from the cell membrane reveal a striking polyhedral pattern reminiscent of a fullerene which arises from the outermost protein in the coat, clathrin. Clathrin assembles from three-legged individual components called triskelions to form a polygonal lattice around the vesicle. Clathrin is a large heterohexameric protein complex composed of three heavy chains and three light chains. Clathrin molecules self-assemble together to make a spherical clathrin lattice structure, a polyhedron made of regular pentagons and hexagons. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. The connection of the clathrin scaffold to the membrane is mediated by clathrin adaptors, which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes. Clathrin-associated adaptor protein (AP) complexes are a stoichiometric coat component of CCVs alongside clathrin itself, and are considered a major clathrin adaptor contributing the CCV formation. ",
"synonyms": "Clathrin-coated vesicular membrane.; ",
"content": "Cytoplasmic vesicle, clathrin-coated vesicle membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "Clathrin-coated vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0030665; clathrin-coated vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Coated pit.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0072",
"definition": "Coated pits are regions of the donor membrane where the assembly of the vesicle coat take place. The coat assembles from soluble protomers such as coat protein complex-I and coat protein complex-II. The components of the coat often define the intracellular sorting station, and contribute to both membrane deformation and local movement of the resulting transport intermediate following scission. During the first steps of the vesicle-mediated membrane transport, coated pits are internalized to form coated vesicles which transport proteins between distinct membrane-bound organelles. ",
"synonyms": null,
"content": "Membrane, coated pit.",
"is_a": null,
"part_of": "Endomembrane system.; ",
"keyword": "KW-0168",
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Contractile vacuole.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0073",
"definition": "A contractile vacuole (CV) complex is a membrane-bound osmoregulatory organelle of fresh water and soil amoebae and protozoa which segregates excess cytosolic water, acquired osmotically, and expel it to the cell exterior, so that the cytosolic osmolarity is kept constant under a given osmotic condition. Depending on the organism, the CV complex (CVC) shows different degrees of specialization of its tubular and vesicular elements. In the most elaborate CVCs of certain ciliates, e.g. Paramecium, a central vacuole, the contractile vacuole or cisterna, is surrounded by radially oriented ampullae or radial arms. These ampullae are connected to a network of channels. Excess cytosolic water, acquired osmotically, is segregated by the radial arms and enters the vacuole, so that the vacuole swells (the fluid- filling phase). The vacuole then rounds (the rounding phase) and the radial arms sever from the vacuole. The vacuole membrane then fuses with the plasma membrane at the pore region and the pore opens. The vacuole shrinks as its fluid is discharged through the pore (the fluid-discharging phase). The pore closes when the fluid has been discharged. The radial arms then reattach to the vacuole, so that the vacuole swells again as the fluid enters from the arms (the next fluid-filling phase). ",
"synonyms": "Contracile vacuole complex; CV; CVC.; ",
"content": "Contractile vacuole.",
"is_a": "Vacuole.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0000331; contractile vacuole; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Contractile vacuole membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0074",
"definition": "The membrane surrounding a contractile vacuole. A contractile vacuole (CV) complex is a membrane-bound osmoregulatory organelle of fresh water and soil amoebae and protozoa which segregates excess cytosolic water, acquired osmotically, and expel it to the cell exterior, so that the cytosolic osmolarity is kept constant under a given osmotic condition. ",
"synonyms": "Contractile vacuolar membrane.; ",
"content": "Contractile vacuole membrane.",
"is_a": "Vacuole membrane.; ",
"part_of": "Contractile vacuole.; ",
"keyword": null,
"gene_ontology": "GO:0031164; contractile vacuolar membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPI-coated vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0075",
"definition": "COPI-coated vesicles mediate the vesicular transport of cargo such as proteins. COPI-coated vesicles are believed to bud from the cis- cisternae of the Golgi apparatus, mediate traffic from the cis-Golgi back to the ER (retrograde), and govern the flow pattern of materials within the Golgi stack. COPI is composed of the coatomer, which is a seven-subunit protein complex that participates in the formation of Golgi-derived coated vesicles. Evidence has also been presented for anterograde intra-Golgi transport mediated by COPI in yeast and mammals. ",
"synonyms": "Coat protein complex I.; ",
"content": "Cytoplasmic vesicle, COPI-coated vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030137; COPI-coated vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPI-coated vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0076",
"definition": "The membrane surrounding a COPI-coated vesicle. COPI-coated vesicles mediate the vesicular transport of cargo such as proteins. COPI-coated vesicles are believed to bud from the cis-cisternae of the Golgi apparatus, mediate traffic from the cis-Golgi back to the ER (retrograde), and govern the flow pattern of materials within the Golgi stack. COPI is composed of the coatomer, which is a seven- subunit protein complex that participates in the formation of Golgi- derived coated vesicles. Evidence has also been presented for anterograde intra-Golgi transport mediated by COPI in yeast and mammals. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, COPI-coated vesicle membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "COPI-coated vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0030663; COPI-coated vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPII-coated vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0077",
"definition": "COPII-coated vesicles mediate the vesicular transport of cargo such as proteins. COPII-coated vesicles are believed to bud from the endoplasmic reticulum be involved in the anterograde transport between the ER to Golgi and travel toward the Endoplasmic reticulum-Golgi intermediate compartment, where they fuse and release their contents (anterograde transport). The COPII coat has five main functional components that are highly conserved in all eukaryotic cells. ",
"synonyms": "Coat protein complexes II; ER to Golgi transport vesicle.; ",
"content": "Cytoplasmic vesicle, COPII-coated vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030134; COPII-coated ER to Golgi transport vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "COPII-coated vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0078",
"definition": "The membrane surrounding a COPII-coated vesicle. COPII-coated vesicles mediate the vesicular transport of cargo such as proteins. COPII- coated vesicles are believed to bud from the endoplasmic reticulum be involved in the anterograde transport between the ER to Golgi and travel toward the Endoplasmic reticulum-Golgi intermediate compartment, where they fuse and release their contents (anterograde transport). The COPII coat has five main functional components that are highly conserved in all eukaryotic cells. ",
"synonyms": "Coat protein complexes II membrane;; ER to Golgi transport vesicle membrane.; ",
"content": "Cytoplasmic vesicle, COPII-coated vesicle membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "COPII-coated vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0012507; ER to Golgi transport vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cornified envelope.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0079",
"definition": "The cornified envelope is a structure which is formed beneath the plasma membrane in terminally differentiating stratified squamous epithelia. It provides a vital physical barrier to these tissues in mammals and consists of a 10 nm thick layer of highly crosslinked insoluble proteins. In the specialized case of the epidermis, a 5 nm thick layer of ceramide lipids is covalently bound to the proteins. These organize extracellular lipids into orderly lamellae and, together, the cell envelope and extracellular lipids are essential for effective physical and water barrier function in the skin. ",
"synonyms": null,
"content": "Cornified envelope.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0001533; cornified envelope; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cvt vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0080",
"definition": "A cvt vesicle is a double membrane-layered vesicle implicated in the cytoplasm to vacuole targeting pathway. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, cvt vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0033107; Cvt vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cvt vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0081",
"definition": "The membrane surrounding a cvt vesicle. A cvt vesicle is a double membrane-layered vesicle implicated in the cytoplasm to vacuole targeting pathway. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, cvt vesicle membrane.",
"is_a": "Cytoplasmic vesicle membrane.; ",
"part_of": "Cvt vesicle.; ",
"keyword": null,
"gene_ontology": "GO:0033110; Cvt vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
}
]
}