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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=80&ordering=-location_identifier",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=40&ordering=-location_identifier",
"results": [
{
"location_identifier": "Secretory vesicle lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0347",
"definition": "The secretory vesicle compartment bounded by the membrane of the secretory vesicle. ",
"synonyms": "Secretory granule lumen.; ",
"content": "Cytoplasmic vesicle, secretory vesicle lumen.",
"is_a": "Cytoplasmic vesicle lumen.; ",
"part_of": "Secretory vesicle.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Secretory vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0244",
"definition": "The secretory vesicle is a vesicle that mediates the vesicular transport of cargo - e.g. hormones or neurotransmitters - from an organelle to specific sites at the cell membrane, where it docks and fuses to release its content. It has been demonstrated that membrane- bound secretory vesicles dock and fuse at porosomes, which are specialized supramolecular structures at the cell membrane. ",
"synonyms": "Secretory granule.; ",
"content": "Cytoplasmic vesicle, secretory vesicle.",
"is_a": "Cytoplasmic vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030133; transport vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Secreted.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0243",
"definition": "Protein located outside the cell membrane(s). ",
"synonyms": null,
"content": "Secreted.",
"is_a": null,
"part_of": null,
"keyword": "KW-0964",
"gene_ontology": "GO:0005576; extracellular region; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Secondary cell wall.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0242",
"definition": "In some plants, and cell types after a maximum size or point in development has been reached, a secondary wall, often layered, is constructed below the primary wall. Unlike the primary wall, it losts plasticity and is made usually of cellulose, hemicellulose and lignin. ",
"synonyms": null,
"content": "Secreted, secondary cell wall.",
"is_a": "Cell wall.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0009531; secondary cell wall; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0241",
"definition": "The membrane surrounding the sarcoplasmic reticulum (SR). ",
"synonyms": null,
"content": "Sarcoplasmic reticulum membrane.",
"is_a": "Membrane.; ",
"part_of": "Endomembrane system.; Sarcoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0033017; sarcoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0240",
"definition": "The lumen of the sarcoplasmic reticulum is the area enclosed by the sarcoplasmic reticulum membrane. ",
"synonyms": null,
"content": "Sarcoplasmic reticulum lumen.",
"is_a": null,
"part_of": "Sarcoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0033018; sarcoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasmic reticulum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0239",
"definition": "The sarcoplasmic reticulum (SR) is a highly specialized form of the smooth endoplasmic reticulum which is dedicated to the regulation of intracellular calcium homeostasis. The SR can be subdivided in at least two well-characterized regions: the terminal cisternae, where the calcium ions are released, and the longitudinal tubules specialized in the uptake of the calcium ions. ",
"synonyms": null,
"content": "Sarcoplasmic reticulum.",
"is_a": null,
"part_of": null,
"keyword": "KW-0703",
"gene_ontology": "GO:0016529; sarcoplasmic reticulum; ",
"annotation": "Not ok: HI Endoplasmic reticulum. ",
"references": null,
"links": null
},
{
"location_identifier": "Sarcoplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0311",
"definition": "The sarcoplasm is the cytoplasm of a muscle fiber or muscle cell or myofiber. ",
"synonyms": null,
"content": "Cytoplasm, sarcoplasm.",
"is_a": "Cytoplasm.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0016528; sarcoplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Sarcomere.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0313",
"definition": "The sarcomere represents the basal contractile unit of striated muscles. A single myofibril is composed of these short structural units arranged end to end, which contract due to the relative sliding of thick (myosin) over thin (actin) filaments. The mammalian sarcomere is ~ 2 mm in length, and can shorten to ~ 70% of its original length during contraction. Structural features of the sarcomere include bundles of parallel thick and thin filaments assembled by two transverse structures, the Z lines and M lines. The Z lines and the M lines are connected by transverse filaments to the sarcolemma or to the neighboring myofibrils. Sarcomeres give to skeletal and cardiac muscles their striated appearance with I bands surrounding the Z lines, followed by A bands. The A bands contain a paler region called the H zone and in the middle the M line. ",
"synonyms": null,
"content": "Cytoplasm, myofibril, sarcomere.",
"is_a": null,
"part_of": "Myofibril.; ",
"keyword": null,
"gene_ontology": "GO:0030017; sarcomere; ",
"annotation": null,
"references": null,
"links": "http://www.sarcomere.org/; "
},
{
"location_identifier": "Sarcolemma.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0238",
"definition": "The sarcolemma is a specialized membrane which surrounds striated muscle fiber cells. It consists of a lipid bilayer typical of a plasma membrane and a thin outer coat of polysaccharide material, called glycocalyx, that contacts the basement membrane and allows the cell to anchor into the tissues that build and support muscle fibers. ",
"synonyms": "Myolemma.; ",
"content": "Cell membrane, sarcolemma.",
"is_a": "Cell membrane.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0042383; sarcolemma; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Ruffle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0301",
"definition": "The portion of the cell membrane surrounding a ruffle. ",
"synonyms": null,
"content": "Cell projection, ruffle membrane.",
"is_a": null,
"part_of": "Cell membrane.; Ruffle.; ",
"keyword": null,
"gene_ontology": "GO:0032587; ruffle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Ruffle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0300",
"definition": "A ruffle is a cell protrusion at the leading edge of a crawling cell. Ruffles are supported by a microfilament meshwork. ",
"synonyms": null,
"content": "Cell projection, ruffle.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0001726; ruffle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rough endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0237",
"definition": "The membrane surrounding the rough endoplasmic reticulum. ",
"synonyms": null,
"content": "Rough endoplasmic reticulum membrane.",
"is_a": "Endoplasmic reticulum membrane.; ",
"part_of": "Rough endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0030867; rough endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rough endoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0236",
"definition": "The rough endoplasmic reticulum lumen is the area enclosed by the rough endoplasmic reticulum membrane. ",
"synonyms": null,
"content": "Rough endoplasmic reticulum lumen.",
"is_a": "Endoplasmic reticulum lumen.; ",
"part_of": "Rough endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0048237; rough endoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rough endoplasmic reticulum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0235",
"definition": "The rough endoplasmic reticulum (RER) is the portion of the ER which is covered with ribosomes. ",
"synonyms": "RER; Rough ER.; ",
"content": "Rough endoplasmic reticulum.",
"is_a": null,
"part_of": "Endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0005791; rough endoplasmic reticulum; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rhoptry membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0234",
"definition": "The membrane surrounding a rhoptry. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, rhoptry membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Rhoptry.; ",
"keyword": null,
"gene_ontology": "GO:0033016; rhoptry membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rhoptry lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0346",
"definition": "The rhoptry compartment bounded by the membrane of a rhoptry. ",
"synonyms": null,
"content": "Cytoplasmic vesicle, secretory vesicle, rhoptry lumen.",
"is_a": "Secretory vesicle lumen.; ",
"part_of": "Rhoptry.; ",
"keyword": null,
"gene_ontology": "GO:0034591; rhoptry lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rhoptry.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0233",
"definition": "The rhoptry is an Apicomplexan parasite organelle. Apicomplexa are named for the unique set of morphologically distinct secretory organelles (refered to as the apical complex)- micronemes, rhoptries and dense granules - whose sequential secretion is required for the invasion of host cells. Rhoptries are twin, membrane-bound, pear- shaped organelles that secrete proteins through their elongated necks at the apical tip of the parasite. ",
"synonyms": "Rhoptries.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, rhoptry.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0020008; rhoptry; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Rhabdomere membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0552",
"definition": "The portion of the plasma membrane surrounding the rhabdomere. ",
"synonyms": null,
"content": "Cell projection, rhabdomere membrane.",
"is_a": "Rhabdomere.; ",
"part_of": "Cell membrane.; ",
"keyword": null,
"gene_ontology": "GO:0033583; rhabdomere membrane; ",
"annotation": "The rhabdomere is a specialised structure of photoreceptor cells found in the compound eyes of arthropods like insects, crustaceans and millipedes. This term should be used only for only for invertebrates such as arthropods and cephalopods . ",
"references": null,
"links": null
},
{
"location_identifier": "Rhabdomere.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0551",
"definition": "A specialized organelle found in the photoreceptor cells of an ommatidium (the individual component of the arthropod compound eye) and the photoreceptor cells in the eye of cephalopods. Composed of thousands of tightly packed microvilli that expand the membrane surface area to accommodate millions of molecules of rhodopsin. Orthologous to the tightly packed membrane discs of the ciliary outer segment in vertebrate photoreceptor cells. ",
"synonyms": null,
"content": "Cell projection, rhabdomere.",
"is_a": "Cell projection.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0016028; rhabdomere; ",
"annotation": "The rhabdomere is a specialised structure of photoreceptor cells found in the compound eyes of arthropods like insects, crustaceans and millipedes, and cephalopods, like octopus and squid. This term should be used only for invertebrates such as arthropods and cephalopods. ",
"references": null,
"links": null
}
]
}