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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=100",
"previous": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=60",
"results": [
{
"location_identifier": "Cyanelle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0082",
"definition": "A cyanelle is a photosynthetic organelle of glaucocystophyte algae. Cyanelles are surrounded by a double membrane and, in between, a peptidoglycan wall. Thylakoid membrane architecture is cyanobacteria- like. Historically, the term cyanelle is derived from a classification as endosymbiotic cyanobacteria, and thus is not fully correct. ",
"synonyms": "Cyanoplast; Muroplast.; ",
"content": "Plastid, cyanelle.",
"is_a": "Plastid.; ",
"part_of": null,
"keyword": "KW-0194",
"gene_ontology": "GO:0009842; cyanelle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cyanelle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0083",
"definition": "The membrane surrounding a cyanelle, a photosynthetic organelle of glaucocystophyte algae. Also used when it is not clear in which cyanelle membrane (outer membrane, inner membrane or thylakoid) a protein is found. ",
"synonyms": null,
"content": "Plastid, cyanelle membrane.",
"is_a": "Plastid membrane.; ",
"part_of": "Cyanelle.; ",
"keyword": null,
"gene_ontology": "GO:0033113; cyanelle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cyanelle thylakoid lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0084",
"definition": "The cyanelle thylakoid lumen is the cyanelle compartment bounded by the thylakoid membranes. ",
"synonyms": null,
"content": "Plastid, cyanelle thylakoid lumen.",
"is_a": "Plastid thylakoid lumen.; ",
"part_of": "Cyanelle thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0033114; cyanelle thylakoid lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cyanelle thylakoid membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0085",
"definition": "The lipid bilayer membrane of any thylakoid within a cyanelle, a photosynthetic organelle of glaucocystophyte algae. ",
"synonyms": null,
"content": "Plastid, cyanelle thylakoid membrane.",
"is_a": "Plastid thylakoid membrane.; ",
"part_of": "Cyanelle thylakoid.; ",
"keyword": null,
"gene_ontology": "GO:0033115; cyanelle thylakoid membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasm.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0086",
"definition": "The cytoplasm is the content of a cell within the plasma membrane and, in eukaryotics cells, surrounding the nucleus. This three-dimensional, jelly-like lattice interconnects and supports the other solid structures. The cytosol (the soluble portion of the cytoplasm outside the organelles) is mostly composed of water and many low molecular weight compounds. In eukaryotes, the cytoplasm also contains a network of cytoplasmic filaments (cytoskeleton). ",
"synonyms": null,
"content": "Cytoplasm.",
"is_a": null,
"part_of": null,
"keyword": "KW-0963",
"gene_ontology": "GO:0005737; cytoplasm; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cilium basal body.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0087",
"definition": "The basal body is a barrel-shaped microtubule-based structure required for the formation of cilia. Basal bodies, structuraly related to and often interconvertible with centrioles, serves as a nucleation site for axoneme growth. ",
"synonyms": "Ciliary basal body; Ciliary kinetosome; Cilium kinetosome.; ",
"content": "Cytoplasm, cytoskeleton, cilium basal body.",
"is_a": null,
"part_of": "Cilium.; Cytoskeleton.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic vesicle.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0088",
"definition": "The cytoplasmic vesicles mediate vesicular transport among the organelles of secretory and endocytic systems. These transport vesicles are classified by the identity of the protein coat used in their formation and also by the cargo they contain, e.g. clathrin-, COPI-, and COPII-coated vesicles, synaptic vesicles, secretory vesicles, phagosomes, etc. ",
"synonyms": null,
"content": "Cytoplasmic vesicle.",
"is_a": "Vesicle.; ",
"part_of": null,
"keyword": "KW-0968",
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoplasmic vesicle membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0089",
"definition": "The membrane surrounding a cytoplasmic vesicle. The cytoplasmic vesicles mediate vesicular transport among the organelles of secretory and endocytic systems. ",
"synonyms": null,
"content": "Cytoplasmic vesicle membrane.",
"is_a": "Membrane.; ",
"part_of": "Cytoplasmic vesicle.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0030659; cytoplasmic vesicle membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytoskeleton.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0090",
"definition": "The cytoskeleton is a dynamic three-dimensional filamentous structure in the cytoplasm. Its roles include maintenance of cell shape, cell movement (in eukaryotes), cytokinesis, and the organization of organelles or organelle-like structures within the cell. The cytoskeleton includes microfilaments (actin-like proteins), microtubules (tubulin-like proteins), the intermediate filaments (mostly in eukaryotes) and the MinD-ParA proteins, which appear to be unique to prokaryotes. ",
"synonyms": null,
"content": "Cytoplasm, cytoskeleton.",
"is_a": null,
"part_of": "Cytoplasm.; ",
"keyword": "KW-0206",
"gene_ontology": "GO:0005856; cytoskeleton; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Cytosol.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0091",
"definition": "The cytosol is the unstructured aqueous phase of the cytoplasm excluding organelles, membranes, and insoluble cytoskeletal components. ",
"synonyms": null,
"content": "Cytoplasm, cytosol.",
"is_a": null,
"part_of": "Cytoplasm.; ",
"keyword": null,
"gene_ontology": "GO:0005829; cytosol; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Desmosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0092",
"definition": "A desmosome (DS) is a button-like adhesion complex that stabilizes epithelial sheets by anchoring the intermediate filament cytoskeleton to the cell junction. Desmosomes are found particularly in tissues subjected to mechanical stress. ",
"synonyms": "DS; Macula adherens.; ",
"content": "Cell junction, desmosome.",
"is_a": "Cell junction.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0030057; desmosome; ",
"annotation": "Add \"Cell membrane\" if the protein is clearly associated with the membrane. ",
"references": null,
"links": "http://celljunctions.med.nyu.edu/desmosomes/desframe.html; "
},
{
"location_identifier": "Early endosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0093",
"definition": "The membrane surrounding the early endosomes, which form a tubulovesicular network spread throughout the cortical cytoplasm of the cell. ",
"synonyms": "Early endosomal membrane.; ",
"content": "Early endosome membrane.",
"is_a": "Endosome membrane.; ",
"part_of": "Early endosome.; ",
"keyword": null,
"gene_ontology": "GO:0031901; early endosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Early endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0094",
"definition": "Early endosomes form a tubulovesicular network spread throughout the cortical cytoplasm of the cell. Early endosomes are the primary sorting station in the endocytic pathway from which endocytosed molecules can be recycled back to the cell membrane or targeted to degradation in the lysosomes. Loaded by endocytosed molecules in 1 to 4 minutes, their acidic luminal pH around 6.0 allows ligand release from recycling receptors. ",
"synonyms": null,
"content": "Early endosome.",
"is_a": null,
"part_of": "Endosome.; ",
"keyword": null,
"gene_ontology": "GO:0005769; early endosome; ",
"annotation": "Compartment specific marker: EEA1; Rab5; Rab4. ",
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0095",
"definition": "The endoplasmic reticulum (ER) is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products. The membrane is a continuation of the outer nuclear membrane, it encloses the cytosol cisternal spaces (or internal lumen), which are continuous with the nuclear periplasmic space. The ER sustains many general functions, including protein synthesis, protein modification, protein folding, insertion of membrane proteins, sequestration of calcium, production of phospholipids and steroids and transport of proteins destined for membranes and secretion. ",
"synonyms": null,
"content": "Endoplasmic reticulum.",
"is_a": null,
"part_of": null,
"keyword": "KW-0256",
"gene_ontology": "GO:0005783; endoplasmic reticulum; ",
"annotation": "Compartment specific marker: PDI; calreticulin; calnexin. ",
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0096",
"definition": "The lumen of the endoplasmic reticulum (ER) is the area enclosed by the endoplasmic reticulum membrane, an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products. ",
"synonyms": null,
"content": "Endoplasmic reticulum lumen.",
"is_a": null,
"part_of": "Endoplasmic reticulum.; ",
"keyword": null,
"gene_ontology": "GO:0005788; endoplasmic reticulum lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0097",
"definition": "The membrane surrounding the endoplasmic reticulum (ER). The endoplasmic reticulum is an extensive network of membrane tubules, vesicles and flattened cisternae (sac-like structures) found throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products. ",
"synonyms": null,
"content": "Endoplasmic reticulum membrane.",
"is_a": "Membrane.; ",
"part_of": "Endoplasmic reticulum.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0005789; endoplasmic reticulum membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0098",
"definition": "The ER-Golgi intermediate compartment is a collection of tubulovesicular membrane clusters in the vicinity of ER exit sites. The ERGIC mediates transport between the endoplasmic reticulum and the Golgi and is the first anterograde/retrograde sorting station in the secretory pathway. ERGIC has not been observed in yeast and plants. ",
"synonyms": "ERGIC; ER-Golgi intermediate compartment; IC;; Intermediate compartment; Vesiculo-tubular cluster; VTC.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005793; endoplasmic reticulum-Golgi intermediate compartment; ",
"annotation": "Compartment specific marker: LMAN1/ERGIC-53 (Also called P-58). ",
"references": null,
"links": null
},
{
"location_identifier": "Endoplasmic reticulum-Golgi intermediate compartment membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0099",
"definition": "The membrane surrounding the ER-Golgi intermediate compartment, which is a collection of tubulovesicular membrane clusters in the vicinity of ER exit sites. ",
"synonyms": "ERGIC membrane; ER-Golgi intermediate compartment membrane;; IC membrane; Intermediate compartment membrane;; Vesiculo-tubular cluster membrane; VTC membrane.; ",
"content": "Endoplasmic reticulum-Golgi intermediate compartment membrane.",
"is_a": "Membrane.; ",
"part_of": "Endoplasmic reticulum-Golgi intermediate compartment.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0033116; endoplasmic reticulum-Golgi intermediate compartment membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0100",
"definition": "The membrane surrounding the endosome. Endosomes are highly dynamic membrane systems involved in transport within the cell, they receive endocytosed cell membrane molecules and sort them for either degradation or recycling back to the cell surface. ",
"synonyms": "Endosomal membrane.; ",
"content": "Endosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Endosome.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0010008; endosome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Endosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0101",
"definition": "Endosomes are highly dynamic membrane systems involved in transport within the cell, they receive endocytosed cell membrane molecules and sort them for either degradation or recycling back to the cell surface. They also receive newly synthesised proteins destined for vacuolar/lysosomal compartments. In certain cell types, endosomal multivesicular bodies may fuse with the cell surface in an exocytic manner. These released vesicles are called exosomes. ",
"synonyms": null,
"content": "Endosome.",
"is_a": null,
"part_of": null,
"keyword": "KW-0967",
"gene_ontology": "GO:0005768; endosome; ",
"annotation": null,
"references": null,
"links": null
}
]
}