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{
"count": 543,
"next": "https://cinder.proteo.info/api/subcellular_locations/?format=api&limit=20&offset=20&ordering=location_identifier",
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"results": [
{
"location_identifier": "A band.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0476",
"definition": "The appearance of the striated muscle is created by a pattern of alternating dark A bands and light I bands. A bands comprise thick filaments of myosin and proteins that bind myosin. They are bisected by the H zone, a paler region where the thick and the thin filaments do not overlap. The exact center of the A band is termed the M line. ",
"synonyms": "A-band; A line.; ",
"content": "Cytoplasm, myofibril, sarcomere, A band.",
"is_a": null,
"part_of": "Sarcomere.; ",
"keyword": null,
"gene_ontology": "GO:0031672; A band; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acidocalcisome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0002",
"definition": "The acidocalcisome is an electron-dense acidic organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. Its limiting membrane possesses a number of pumps and exchangers for the uptake and release of these elements. The acidocalcisome does not belong to the endocytic pathway and may represent a branch of the secretory pathway in trypanosomatids and apicomplexan parasites. The acidocalcisome is possibly involved in polyphosphate and cation storage and in adaptation of these microoganisms to environmental stress. ",
"synonyms": null,
"content": "Acidocalcisome.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0020022; acidocalcisome; ",
"annotation": null,
"references": "PubMed=15738951; DOI=10.1038/nrmicro1097;; ",
"links": null
},
{
"location_identifier": "Acidocalcisome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0316",
"definition": "The acidocalcisome compartment bounded by the acidocalcisomal membrane. ",
"synonyms": "Acidocalcisomal lumen.; ",
"content": "Acidocalcisome lumen.",
"is_a": null,
"part_of": "Acidocalcisome.; ",
"keyword": null,
"gene_ontology": "GO:0033985; acidocalcisome lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acidocalcisome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0003",
"definition": "The membrane of an acidocalcisome. ",
"synonyms": "Acidocalcisomal membrane.; ",
"content": "Acidocalcisome membrane.",
"is_a": "Membrane.; ",
"part_of": "Acidocalcisome.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0033102; acidocalcisome membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acrosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0007",
"definition": "The acrosome is a large lysosome-like vesicle overlying the sperm nucleus. This spermatid specific organelle, derived from the Golgi during spermatogenesis, contains both unique acrosomal enzymes and common enzymes associated with lysosomes in somatic cells. Only sperm that have undergone the acrosome reaction can fuse with egg plasma membrane. The acrosome reaction is characterized by multiple fusions of the outer acrosomal membrane with the sperm cell membrane. ",
"synonyms": "Acrosomal vesicle.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, acrosome.",
"is_a": "Secretory vesicle.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0001669; acrosomal vesicle; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acrosome inner membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0004",
"definition": "The portion of the acrosomal membrane closely associated with the anterior region of the nuclear envelope. ",
"synonyms": "Acrosomal inner membrane; IAM; Inner acrosomal membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane.",
"is_a": null,
"part_of": "Acrosome membrane.; ",
"keyword": null,
"gene_ontology": "GO:0002079; inner acrosomal membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acrosome lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0005",
"definition": "The lumen of the acrosome. ",
"synonyms": "Acrosomal lumen.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, acrosome lumen.",
"is_a": "Secretory vesicle lumen.; ",
"part_of": "Acrosome.; ",
"keyword": null,
"gene_ontology": "GO:0043160; acrosomal lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acrosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0006",
"definition": "The membrane of the acrosome. ",
"synonyms": "Acrosomal membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, acrosome membrane.",
"is_a": "Secretory vesicle membrane.; ",
"part_of": "Acrosome.; Endomembrane system.; ",
"keyword": null,
"gene_ontology": "GO:0002080; acrosomal membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Acrosome outer membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0447",
"definition": "The portion of the acrosomal membrane just beneath the sperm cell membrane. ",
"synonyms": "Acrosomal outer membrane; Outer acrosomal membrane.; ",
"content": "Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane.",
"is_a": null,
"part_of": "Acrosome membrane.; ",
"keyword": null,
"gene_ontology": "GO:0002081; outer acrosomal membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Actin patch.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0008",
"definition": "The actin patch is a highly dynamic actin structure in fungi required primarily for endocytosis but possibly also coupled to exocytosis. Actin patches are highly motile, they first assemble at sites of polarized cell growth and then move slowly and nondirectionally along the cell cortex. ",
"synonyms": "Actin cortical patch.; ",
"content": "Cytoplasm, cytoskeleton, actin patch.",
"is_a": null,
"part_of": "Cytoskeleton.; ",
"keyword": null,
"gene_ontology": "GO:0030479; actin cortical patch; ",
"annotation": "The actin patch is a specialised structure which is specific to fungi so this term should be used only for fungal species. ",
"references": null,
"links": null
},
{
"location_identifier": "Adherens junction.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0009",
"definition": "The adherens junction is an adhesion complex that localizes close to the apical membrane in epithelial cells. These junctions join the actin cytoskeleton to the plasma membrane to form adhesive contacts between cells or between cells and extracellular matrix. AJs mediate both cell adhesion and signaling. ",
"synonyms": "AJ; ZA; Zonula adherens.; ",
"content": "Cell junction, adherens junction.",
"is_a": "Cell junction.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0005912; adherens junction; ",
"annotation": "Add \"Cell membrane\" if the protein is clearly associated with the membrane. ",
"references": null,
"links": null
},
{
"location_identifier": "Aleurone grain.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0010",
"definition": "The aleurone grain (protein body), is a specialized dry vacuole where storage proteins accumulate in a stable form in seeds, usually in the endosperm. Cells containing aleurones form the aleurone layer. These act as a source of amino acids for various synthetic activities during germination, but also represent immensely important nutritional sources for humans and ruminants. In most seeds, the aleuron grains contain three morphologically distinct regions: the matrix, crystalloid, and globoid. ",
"synonyms": "Protein body.; ",
"content": "Vacuole, aleurone grain.",
"is_a": "Vacuole.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0033095; aleurone grain; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Aleurone grain lumen.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0317",
"definition": "The aleurone grain compartment bounded by the aleurone grain membrane. ",
"synonyms": "Protein body lumen.; ",
"content": "Vacuole, aleurone grain lumen.",
"is_a": "Vacuole lumen.; ",
"part_of": "Aleurone grain.; ",
"keyword": null,
"gene_ontology": "GO:0034422; aleurone grain lumen; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Aleurone grain membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0011",
"definition": "The membrane of an aleurone grain. ",
"synonyms": "Protein body membrane.; ",
"content": "Vacuole, aleurone grain membrane.",
"is_a": "Vacuole membrane.; ",
"part_of": "Aleurone grain.; ",
"keyword": null,
"gene_ontology": "GO:0032578; aleurone grain membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Amyloplast.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0012",
"definition": "The amyloplast is a colorless plant plastid that forms and stores starch. Amyloplasts are found in many tissues, particularly in storage tissues. They are found in both photosynthetic and parasitic plants, i.e. even in plants that are not capable of photosynthesis. Many amyloplast proteins are also expressed in photosynthetic tissue. ",
"synonyms": null,
"content": "Plastid, amyloplast.",
"is_a": "Plastid.; ",
"part_of": null,
"keyword": "KW-0035",
"gene_ontology": "GO:0009501; amyloplast; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Amyloplast inner membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0013",
"definition": "The inner membrane of an amyloplast. ",
"synonyms": "Inner amyloplastic membrane.; ",
"content": "Plastid, amyloplast inner membrane.",
"is_a": "Amyloplast membrane.; Plastid inner membrane.; ",
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0033098; amyloplast inner membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Amyloplast membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0014",
"definition": "The membrane surrounding the amyloplast. Also used when it is not clear in which amyloplast membrane a protein is found. ",
"synonyms": null,
"content": "Plastid, amyloplast membrane.",
"is_a": "Plastid membrane.; ",
"part_of": "Amyloplast.; ",
"keyword": null,
"gene_ontology": "GO:0033097; amyloplast membrane; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Anammoxosome.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0491",
"definition": "The anammoxosome is a large intracytoplasmic compartment bounded by a single bilayer, ladderane-lipid-containing membrane present in bacteria that perform anaerobic ammonium oxidation (anammox). This organelle is the site of the anammox process, in which nitrite is used as the electron acceptor in the conversion of ammonium to dinitrogen (N2) gas and water. Anammox bacteria belong to the phylum Planctomycetes and are recognized as major players in the global nitrogen cycle. ",
"synonyms": null,
"content": "Anammoxosome.",
"is_a": null,
"part_of": null,
"keyword": null,
"gene_ontology": "GO:0044222; anammoxosome; ",
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Anammoxosome membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0492",
"definition": "The membrane of the anammoxosome, a single bilayer membrane that contains unusual lipids, i.e. the so-called ladderane lipids, which appear to be unique for anammox bacteria. ",
"synonyms": null,
"content": "Anammoxosome membrane.",
"is_a": "Membrane.; ",
"part_of": "Anammoxosome.; ",
"keyword": null,
"gene_ontology": null,
"annotation": null,
"references": null,
"links": null
},
{
"location_identifier": "Apical cell membrane.",
"topology_identifier": null,
"orientation_identifier": null,
"accession": "SL-0015",
"definition": "The fraction of the cell membrane at the apical end of the cell, which faces the outside world or the lumen of the cavity. ",
"synonyms": "Apical plasma membrane.; ",
"content": "Apical cell membrane.",
"is_a": null,
"part_of": "Cell membrane.; ",
"keyword": null,
"gene_ontology": "GO:0016324; apical plasma membrane; ",
"annotation": null,
"references": null,
"links": null
}
]
}